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Murcko scaffold

Ring system with 2 rings and 14 atoms

46 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 14
Chemicals: 46
With full pages: 1

Scaffold SMILES

O=C(CCc1ccccc1)N1CCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CCc1ccccc1)N1CCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 46 of 46 chemicals

1-(Azetidin-1-yl)-3-(3,5-ditert-butyl-4-hydroxyphenyl)propan-1-one chemical structure, C20H31NO2, CAS 878266-06-9

1-(Azetidin-1-yl)-3-(3,5-ditert-butyl-4-hydroxyphenyl)propan-1-one

CAS 878266-06-9C₂₀H₃₁NO₂

2-Amino-1-(3-hydroxy-1-azetidinyl)-3-phenyl-1-propanone chemical structure, C12H16N2O2, CAS 1236264-30-4

2-Amino-1-(3-hydroxy-1-azetidinyl)-3-phenyl-1-propanone

CAS 1236264-30-4C₁₂H₁₆N₂O₂

(S)-2-Amino-1-(azetidin-1-yl)-3-phenylpropan-1-one hydrochloride chemical structure, C12H17ClN2O, CAS 1162654-35-4

(S)-2-Amino-1-(azetidin-1-yl)-3-phenylpropan-1-one hydrochloride

CAS 1162654-35-4C₁₂H₁₇ClN₂O

(R)-2-Amino-1-azetidin-1-yl-3-(2-br chemical structure, C12H16BrClN2O, CAS 1162654-36-5

(R)-2-Amino-1-azetidin-1-yl-3-(2-br

CAS 1162654-36-5C₁₂H₁₆BrClN₂O

(2E)-N-[(2S)-1-(Azetidin-1-yl)-1-oxo-3-phenylpropan-2-yl]-2-(methoxyimino)acetamide chemical structure, C15H19N3O3, CAS 1204333-03-8

(2E)-N-[(2S)-1-(Azetidin-1-yl)-1-oxo-3-phenylpropan-2-yl]-2-(methoxyimino)acetamide

CAS 1204333-03-8C₁₅H₁₉N₃O₃

3-(3-Bromophenyl)-1-(3-hydroxyazetidin-1-yl)propan-1-one chemical structure, C12H14BrNO2, CAS 1339656-61-9

3-(3-Bromophenyl)-1-(3-hydroxyazetidin-1-yl)propan-1-one

CAS 1339656-61-9C₁₂H₁₄BrNO₂

1-(3-Phenylpropanoyl)azetidine-3-carboxylic acid chemical structure, C13H15NO3, CAS 1407081-44-0

1-(3-Phenylpropanoyl)azetidine-3-carboxylic acid

CAS 1407081-44-0C₁₃H₁₅NO₃

3-(4-Aminophenyl)-1-(azetidin-1-yl)propan-1-one chemical structure, C12H16N2O, CAS 1374666-20-2

3-(4-Aminophenyl)-1-(azetidin-1-yl)propan-1-one

CAS 1374666-20-2C₁₂H₁₆N₂O

1-(Azetidin-1-yl)-3-(4-nitrophenyl)propan-1-one chemical structure, C12H14N2O3, CAS 1374666-19-9

1-(Azetidin-1-yl)-3-(4-nitrophenyl)propan-1-one

CAS 1374666-19-9C₁₂H₁₄N₂O₃

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(4-methoxyphenyl)propan-1-one chemical structure, C17H25NO4S, CAS 1797874-51-1

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(4-methoxyphenyl)propan-1-one

CAS 1797874-51-1C₁₇H₂₅NO₄S

3-(5-Bromo-2-methoxyphenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one chemical structure, C17H24BrNO4S, CAS 1797145-72-2

3-(5-Bromo-2-methoxyphenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one

CAS 1797145-72-2C₁₇H₂₄BrNO₄S

3-(2-Bromophenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one chemical structure, C16H22BrNO3S, CAS 1797692-56-8

3-(2-Bromophenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one

CAS 1797692-56-8C₁₆H₂₂BrNO₃S

3-(3-Chlorophenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one chemical structure, C16H22ClNO3S, CAS 1797692-63-7

3-(3-Chlorophenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one

CAS 1797692-63-7C₁₆H₂₂ClNO₃S

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(o-tolyl)propan-1-one chemical structure, C17H25NO3S, CAS 1797632-58-6

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(o-tolyl)propan-1-one

CAS 1797632-58-6C₁₇H₂₅NO₃S

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(4-(methylsulfonyl)phenyl)propan-1-one chemical structure, C17H25NO5S2, CAS 1797846-30-0

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(4-(methylsulfonyl)phenyl)propan-1-one

CAS 1797846-30-0C₁₇H₂₅NO₅S₂

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(4-(trifluoromethyl)phenyl)propan-1-one chemical structure, C17H22F3NO3S, CAS 1797086-60-2

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(4-(trifluoromethyl)phenyl)propan-1-one

CAS 1797086-60-2C₁₇H₂₂F₃NO₃S

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(2,3,4-trimethoxyphenyl)propan-1-one chemical structure, C19H29NO6S, CAS 1798035-17-2

1-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-(2,3,4-trimethoxyphenyl)propan-1-one

CAS 1798035-17-2C₁₉H₂₉NO₆S

3-(3-Chloro-4-fluorophenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one chemical structure, C16H21ClFNO3S, CAS 1797304-36-9

3-(3-Chloro-4-fluorophenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one

CAS 1797304-36-9C₁₆H₂₁ClFNO₃S

3-(4-Chloro-3-(trifluoromethyl)phenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one chemical structure, C17H21ClF3NO3S, CAS 1797846-33-3

3-(4-Chloro-3-(trifluoromethyl)phenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one

CAS 1797846-33-3C₁₇H₂₁ClF₃NO₃S

3-(3-Fluoro-4-methylphenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one chemical structure, C17H24FNO3S, CAS 1797885-85-8

3-(3-Fluoro-4-methylphenyl)-1-(3-(isobutylsulfonyl)azetidin-1-yl)propan-1-one

CAS 1797885-85-8C₁₇H₂₄FNO₃S

4-(3-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-oxopropyl)benzonitrile chemical structure, C17H22N2O3S, CAS 1796970-35-8

4-(3-(3-(Isobutylsulfonyl)azetidin-1-yl)-3-oxopropyl)benzonitrile

CAS 1796970-35-8C₁₇H₂₂N₂O₃S

1-(Azetidin-1-yl)-3-(2-chlorophenyl)propan-1-one chemical structure, C12H14ClNO, CAS 1625621-21-7

1-(Azetidin-1-yl)-3-(2-chlorophenyl)propan-1-one

CAS 1625621-21-7C₁₂H₁₄ClNO

3-(4-Bromophenyl)-1-(3-methoxyazetidin-1-yl)propan-1-one chemical structure, C13H16BrNO2, CAS 1645463-31-5

3-(4-Bromophenyl)-1-(3-methoxyazetidin-1-yl)propan-1-one

CAS 1645463-31-5C₁₃H₁₆BrNO₂

1-(3-Hydroxyazetidin-1-yl)-3-phenylbutan-1-one chemical structure, C13H17NO2, CAS 2072283-61-3

1-(3-Hydroxyazetidin-1-yl)-3-phenylbutan-1-one

CAS 2072283-61-3C₁₃H₁₇NO₂