Murcko scaffold
Ring system with 2 rings and 13 atoms
94 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 94
- With full pages
- 4
Scaffold SMILES
c1ccc(COCC2CCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 94 chemicals
![3-[(Benzyloxy)methyl]cyclobutan-1-ol chemical structure, C12H16O2, CAS 197167-53-6](/s/KVQOEODTOJCIPA-UHFFFAOYSA-N.svg)
3-[(Benzyloxy)methyl]cyclobutan-1-ol
CAS 197167-53-6C12H16O2
![3-[(Benzyloxy)methyl]-1-{[(tert-butoxy)carbonyl]amino}cyclobutane-1-carboxylic acid chemical structure, C18H25NO5, CAS 191110-91-5](/s/QWYUECDMYRFNNF-UHFFFAOYSA-N.svg)
3-[(Benzyloxy)methyl]-1-{[(tert-butoxy)carbonyl]amino}cyclobutane-1-carboxylic acid
CAS 191110-91-5C18H25NO5
(1-((Benzyloxy)methyl)cyclobutyl)methanol
CAS 568591-39-9C13H18O2
Ethyl 1-benzyloxymethylcyclobutanecarboxylate
CAS 114671-88-4C15H20O3
![1-Amino-3-[(benzyloxy)methyl]cyclobutane-1-carboxylic acid chemical structure, C13H17NO3, CAS 191110-90-4](/s/CCTNQVJGLNETLT-UHFFFAOYSA-N.svg)
1-Amino-3-[(benzyloxy)methyl]cyclobutane-1-carboxylic acid
CAS 191110-90-4C13H17NO3
![{[(3,3-Dimethoxycyclobutyl)methoxy]methyl}benzene chemical structure, C14H20O3, CAS 583830-08-4](/s/MXXNBOJOWZJBSL-UHFFFAOYSA-N.svg)
{[(3,3-Dimethoxycyclobutyl)methoxy]methyl}benzene
CAS 583830-08-4C14H20O3
![cis 3-[(Benzyloxy)methyl]cyclobutyl methanesulfonate chemical structure, C13H18O4S, CAS 847416-95-9](/s/RMMAUKPKGLGOCQ-UHFFFAOYSA-N.svg)
cis 3-[(Benzyloxy)methyl]cyclobutyl methanesulfonate
CAS 847416-95-9C13H18O4S
cis-3-((Benzyloxy)methyl)cyclobutanamine
CAS 847416-94-8C12H17NO
![Methyl 1-[[(1,1-dimethylethoxy)carbonyl]amino]-3-[(phenylmethoxy)methyl]cyclobutanecarboxylate chemical structure, C19H27NO5, CAS 191110-92-6](/s/RAYZFYRHFWLXQG-UHFFFAOYSA-N.svg)
Methyl 1-[[(1,1-dimethylethoxy)carbonyl]amino]-3-[(phenylmethoxy)methyl]cyclobutanecarboxylate
CAS 191110-92-6C19H27NO5
(3-Benzyloxymethyl-cyclobutyl)-methanol
CAS 890529-83-6C13H18O2
cis-3-Benzyloxymethyl-cyclobutanecarbaldehyde
CAS 2383942-79-6C13H16O2
(3-Benzyloxymethyl-cyclobutyl)-acetic acid methyl ester
CAS 1217800-58-2C15H20O3
(((1-(Bromomethyl)cyclobutyl)methoxy)methyl)benzene
CAS 1483150-26-0C13H17BrO
(cis-3-(Benzyloxymethyl)cyclobutoxy)(tert-butyl)dimethylsilane
CAS 959749-92-9C18H30O2Si
cis-3-Benzyloxymethylcyclobutanol methyl ether
CAS 959600-77-2C13H18O2
3-((Benzyloxy)methyl)cyclobutanecarboxylic acid
CAS 1363381-57-0C13H16O3
![1-[[(4-Methoxyphenyl)methoxy]methyl]cyclobutanemethanol chemical structure, C14H20O3, CAS 738624-96-9](/s/DSNKHYXVMDIJMQ-UHFFFAOYSA-N.svg)
1-[[(4-Methoxyphenyl)methoxy]methyl]cyclobutanemethanol
CAS 738624-96-9C14H20O3
1-Amino-3-((benzyloxy)methyl)cyclobutane-1-carbonitrile
CAS 1616601-51-4C13H16N2O
![({[1-(Chloromethyl)cyclobutyl]methoxy}methyl)benzene chemical structure, C13H17ClO, CAS 1598102-37-4](/s/IHMPIOASHINELT-UHFFFAOYSA-N.svg)
({[1-(Chloromethyl)cyclobutyl]methoxy}methyl)benzene
CAS 1598102-37-4C13H17ClO
![Methyl 1-amino-3-[(benzyloxy)methyl]cyclobutane-1-carboxylate chemical structure, C14H19NO3, CAS 1785587-52-1](/s/GJSXHWPHSGSBOY-UHFFFAOYSA-N.svg)
Methyl 1-amino-3-[(benzyloxy)methyl]cyclobutane-1-carboxylate
CAS 1785587-52-1C14H19NO3
![Ethyl 1-amino-3-[(benzyloxy)methyl]cyclobutane-1-carboxylate chemical structure, C15H21NO3, CAS 1785366-02-0](/s/CHSCSXLMFNHJOY-UHFFFAOYSA-N.svg)
Ethyl 1-amino-3-[(benzyloxy)methyl]cyclobutane-1-carboxylate
CAS 1785366-02-0C15H21NO3
![1-[3-(Benzyloxymethyl)cyclobutyl]ethanol chemical structure, C14H20O2, CAS 1940136-07-1](/s/WBHXFYNRMMEHRT-UHFFFAOYSA-N.svg)
1-[3-(Benzyloxymethyl)cyclobutyl]ethanol
CAS 1940136-07-1C14H20O2
2-(Benzyloxymethyl)cyclobutanol
CAS 2168976-27-8C12H16O2
1-((Benzyloxy)methyl)cyclobutane-1-carbaldehyde
CAS 1333467-27-8C13H16O2
- 3-[(Benzyloxy)methyl]cyclobutan-1-amine hydrochloride2172081-96-6C12H18ClNO
- 1-Amino-3-[(benzyloxy)methyl]cyclobutane-1-carboxylic acid hydrochloride2171865-60-2C13H18ClNO3
- Methyl 1-amino-3-((benzyloxy)methyl)cyclobutane-1-carboxylate hydrochloride2171979-10-3C14H20ClNO3
- (((1-Ethynylcyclobutyl)methoxy)methyl)benzene2068725-66-4C14H16O
- N-{3-[(Benzyloxy)methyl]cyclobutyl}-2-chloroacetamide2411247-72-6C14H18ClNO2
- (E)-4-(Dimethylamino)-N-[3-(phenylmethoxymethyl)cyclobutyl]but-2-enamide2411325-45-4C18H26N2O2
- N-[3-(Phenylmethoxymethyl)cyclobutyl]prop-2-enamide2411217-17-7C15H19NO2
- (1S,2R)-2-(Benzyloxymethyl)cyclobutanol2306246-34-2C12H16O2
- 3-[(Benzyloxy)methyl]-1-acetamidocyclobutane-1-carboxylic acid2637118-36-4C15H19NO4
- cis-1-(Aminomethyl)-3-(benzyloxymethyl)cyclobutanol2725791-13-7C13H19NO2
- (1R,2S)-2-(Benzyloxymethyl)cyclobutanol2740592-88-3C12H16O2
- (1R,2R)-2-(Benzyloxymethyl)cyclobutanol2738979-40-1C12H16O2
- ({[1-(Bromomethyl)-3-methylcyclobutyl]methoxy}methyl)benzene2137860-74-1C14H19BrO
- ({[1-(Chloromethyl)-3-methylcyclobutyl]methoxy}methyl)benzene2137958-48-4C14H19ClO
- ({[1-(Chloromethyl)-3,3-difluorocyclobutyl]methoxy}methyl)benzene2137867-34-4C13H15ClF2O
- 1-[2-Bromo-1-(cyclobutylmethoxy)ethyl]-2-fluorobenzene2138118-72-4C13H16BrFO
- 1-[2-Bromo-1-(cyclobutylmethoxy)ethyl]-4-chlorobenzene2138563-81-0C13H16BrClO
- 1-[1-(Cyclobutylmethoxy)-2-iodoethyl]-4-methylbenzene2138538-41-5C14H19IO
- 1-[1-(Cyclobutylmethoxy)-2-iodoethyl]-3-fluorobenzene2138563-83-2C13H16FIO
- 1-Bromo-3-[1-(cyclobutylmethoxy)-2-iodoethyl]benzene2138517-07-2C13H16BrIO
- [1-(1-Cyclobutylethoxy)-2-iodoethyl]benzene2138525-28-5C14H19IO
- [1-Bromo-2-(cyclobutylmethoxy)propan-2-yl]benzene2138586-54-4C14H19BrO
- 1-[2-Bromo-1-(cyclobutylmethoxy)ethyl]-2-methylbenzene2138040-66-9C14H19BrO
- 1-[2-Bromo-1-(cyclobutylmethoxy)ethyl]-4-methylbenzene2138040-71-6C14H19BrO
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(OCc1ccccc1)N1CCC121 chemicals
c1ccc(COCC2COC2)cc15 chemicals
c1ccc(CNCC2CCC2)cc14 chemicals
O=C(OCc1ccccc1)C1CCC14 chemicals
O=C(NCc1ccccc1)C1CCC13 chemicals
c1ccc(COCC2CNC2)cc13 chemicals
O=C1CC(COCc2ccccc2)C12 chemicals
O=C1CN(C(=O)OCc2ccccc2)C12 chemicals
O=C(CC1CCC1)Nc1ccccc12 chemicals
O=C(CCc1ccccc1)N1CCC11 chemical
C1CNCC(CCCC2CNC2)C11 chemical
O=S(=O)(OCC1CCC1)c1ccccc11 chemical