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Murcko scaffold

Ring system with 3 rings and 19 atoms

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
22
With full pages
3
Scaffold SMILES

O=C(Nc1ccc2ccc(=O)oc2c1)C1CCCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc2ccc(=O)oc2c1)C1CCCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

Glycylprolyl-4-methylcoumaryl-7-amide chemical structure, C17H19N3O4, CAS 67341-40-6
Glycylprolyl-4-methylcoumaryl-7-amide
CAS 67341-40-6C17H19N3O4
L-Proline 7-amido-4-methylcoumarin hydrobromide chemical structure, C15H17BrN2O3, CAS 115388-93-7
L-Proline 7-amido-4-methylcoumarin hydrobromide
CAS 115388-93-7C15H17BrN2O3
(S)-N-(4-Methyl-2-oxo-2H-chromen-7-yl)pyrrolidine-2-carboxamide chemical structure, C15H16N2O3, CAS 96643-94-6
(S)-N-(4-Methyl-2-oxo-2H-chromen-7-yl)pyrrolidine-2-carboxamide
CAS 96643-94-6C15H16N2O3
Pro-AMC chemical structure, C15H16N2O3, CAS 221208-87-3
Pro-AMC
CAS 221208-87-3C15H16N2O3
H-Hyp-amc chemical structure, C15H16N2O4, CAS 77471-43-3
H-Hyp-amc
CAS 77471-43-3C15H16N2O4
(2S)-1-[(2S)-2,6-Diaminohexanoyl]-N-(4-methyl-2-oxochromen-7-yl)pyrrolidine-2-carboxamide chemical structure, C21H28N4O4, CAS 133066-53-2
(2S)-1-[(2S)-2,6-Diaminohexanoyl]-N-(4-methyl-2-oxochromen-7-yl)pyrrolidine-2-carboxamide
CAS 133066-53-2C21H28N4O4
Gly-Pro-7-amido-4-methylcoumarin hydrobromide chemical structure, C17H20BrN3O4, CAS 1100744-51-1
Gly-Pro-7-amido-4-methylcoumarin hydrobromide
CAS 1100744-51-1C17H20BrN3O4
GP-Amc chemical structure, C24H27N3O7S, CAS 67341-42-8
GP-Amc
CAS 67341-42-8C24H27N3O7S
Suc-gly-pro-amc chemical structure, C21H23N3O7, CAS 80049-85-0
Suc-gly-pro-amc
CAS 80049-85-0C21H23N3O7
Glycyl-L-proline 7-amido-4-methylcoumarin hydrobromide chemical structure, C17H20BrN3O4, CAS 115035-46-6
Glycyl-L-proline 7-amido-4-methylcoumarin hydrobromide
CAS 115035-46-6C17H20BrN3O4
L-Hydroxyproline 7-amido-4-methylcoumarin hydrochloride chemical structure, C15H17ClN2O4, CAS 1135372-06-3
L-Hydroxyproline 7-amido-4-methylcoumarin hydrochloride
CAS 1135372-06-3C15H17ClN2O4
H-Ala-Pro-AFC chemical structure, C18H18F3N3O4, CAS 125791-92-6
H-Ala-Pro-AFC
CAS 125791-92-6C18H18F3N3O4
Ac-Gly-Pro-AFC chemical structure, C19H18F3N3O5, CAS 886993-02-8
Ac-Gly-Pro-AFC
CAS 886993-02-8C19H18F3N3O5
L-Alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-prolinamide chemical structure, C18H21N3O4, CAS 658058-21-0
L-Alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-prolinamide
CAS 658058-21-0C18H21N3O4
(2S)-1-[(2S)-2-Amino-4-methylpentanoyl]-N-(4-methyl-2-oxochromen-7-yl)pyrrolidine-2-carboxamide chemical structure, C21H27N3O4, CAS 130571-32-3
(2S)-1-[(2S)-2-Amino-4-methylpentanoyl]-N-(4-methyl-2-oxochromen-7-yl)pyrrolidine-2-carboxamide
CAS 130571-32-3C21H27N3O4
Gly-Pro-Mca Tosylate chemical structure, C24H27N3O7S
Gly-Pro-Mca Tosylate
C24H27N3O7S
H-Gly-Ala-Pro-AFC chemical structure, C20H21F3N4O5, CAS 219137-81-2
H-Gly-Ala-Pro-AFC
CAS 219137-81-2C20H21F3N4O5
Met-Gly-Pro-AMC chemical structure, C22H28N4O5S, CAS 1926163-52-1
Met-Gly-Pro-AMC
CAS 1926163-52-1C22H28N4O5S
H-Met-Gly-Pro-AMC HCl chemical structure, C22H29ClN4O5S, CAS 1926163-53-2
H-Met-Gly-Pro-AMC HCl
CAS 1926163-53-2C22H29ClN4O5S
H-Lys-Pro-AMC Hydrochloride chemical structure, C21H29ClN4O4, CAS 2237216-60-1
H-Lys-Pro-AMC Hydrochloride
CAS 2237216-60-1C21H29ClN4O4
(S)-N-(4-Methyl-2-oxo-2H-chromen-7-yl)pyrrolidine-2-carboxamide hydrochloride chemical structure, C15H17ClN2O3, CAS 129409-03-6
(S)-N-(4-Methyl-2-oxo-2H-chromen-7-yl)pyrrolidine-2-carboxamide hydrochloride
CAS 129409-03-6C15H17ClN2O3
tert-Butyl ((R)-1-((S)-2-((4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-yl)carbamate chemical structure, C23H29N3O6, CAS 2378323-92-1
tert-Butyl ((R)-1-((S)-2-((4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-yl)carbamate
CAS 2378323-92-1C23H29N3O6