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Murcko scaffold

N-Phenylthiazole-5-carboxamide scaffold

99 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 14
Chemicals: 99
With full pages: 11

Scaffold SMILES

O=C(Nc1ccccc1)c1cncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-Phenylthiazole-5-carboxamide page

Murcko scaffold O=C(Nc1ccccc1)c1cncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 99 chemicals

2-Amino-N-(2,4,6-trimethylphenyl)-5-thiazolecarboxamide chemical structure, C13H15N3OS, CAS 302957-98-8

2-Amino-N-(2,4,6-trimethylphenyl)-5-thiazolecarboxamide

CAS 302957-98-8C₁₃H₁₅N₃OS

2-Chloro-N-(2,6-diisopropylphenyl)thiazole-5-carboxamide chemical structure, C16H19ClN2OS, CAS 1101105-46-7

2-Chloro-N-(2,6-diisopropylphenyl)thiazole-5-carboxamide

CAS 1101105-46-7C₁₆H₁₉ClN₂OS

2-Chloro-N-(3,5-dimethoxyphenyl)-5-thiazolecarboxamide chemical structure, C12H11ClN2O3S, CAS 1101105-48-9

2-Chloro-N-(3,5-dimethoxyphenyl)-5-thiazolecarboxamide

CAS 1101105-48-9C₁₂H₁₁ClN₂O₃S

2-Chloro-N-(2-methylphenyl)-5-thiazolecarboxamide chemical structure, C11H9ClN2OS, CAS 1101105-79-6

2-Chloro-N-(2-methylphenyl)-5-thiazolecarboxamide

CAS 1101105-79-6C₁₁H₉ClN₂OS

2-Chloro-N-phenyl-5-thiazolecarboxamide chemical structure, C10H7ClN2OS, CAS 1101105-73-0

2-Chloro-N-phenyl-5-thiazolecarboxamide

CAS 1101105-73-0C₁₀H₇ClN₂OS

tert-Butyl N-{5-[(2,6-dimethylphenyl)carbamoyl]-4-methyl-1,3-thiazol-2-yl}carbamate chemical structure, C18H23N3O3S, CAS 302958-40-3

tert-Butyl N-{5-[(2,6-dimethylphenyl)carbamoyl]-4-methyl-1,3-thiazol-2-yl}carbamate

CAS 302958-40-3C₁₈H₂₃N₃O₃S

N-(2-Chloro-6-methylphenyl)-2-(methylamino)thiazole-5-carboxamide chemical structure, C12H12ClN3OS, CAS 302963-04-8

N-(2-Chloro-6-methylphenyl)-2-(methylamino)thiazole-5-carboxamide

CAS 302963-04-8C₁₂H₁₂ClN₃OS

2-Bromo-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide chemical structure, C11H8BrClN2OS, CAS 302964-07-4

2-Bromo-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide

CAS 302964-07-4C₁₁H₈BrClN₂OS

2-Amino-N-(2,6-dimethylphenyl)-5-thiazolecarboxamide chemical structure, C12H13N3OS, CAS 302964-26-7

2-Amino-N-(2,6-dimethylphenyl)-5-thiazolecarboxamide

CAS 302964-26-7C₁₂H₁₃N₃OS

2-Amino-4-methyl-N-phenyl-1,3-thiazole-5-carboxamide, trifluoroacetic acid chemical structure, C13H12F3N3O3S, CAS 302957-94-4

2-Amino-4-methyl-N-phenyl-1,3-thiazole-5-carboxamide, trifluoroacetic acid

CAS 302957-94-4C₁₃H₁₂F₃N₃O₃S

2-Amino-N-(2-chloro-6-methylphenyl)-4-methyl-5-thiazolecarboxamide chemical structure, C12H12ClN3OS, CAS 21673-88-1

2-Amino-N-(2-chloro-6-methylphenyl)-4-methyl-5-thiazolecarboxamide

CAS 21673-88-1C₁₂H₁₂ClN₃OS

4-Methyl-2-[(methylsulfonyl)amino]-N-(2,4,6-trimethylphenyl)-5-thiazolecarboxamide chemical structure, C15H19N3O3S2, CAS 302961-09-7

4-Methyl-2-[(methylsulfonyl)amino]-N-(2,4,6-trimethylphenyl)-5-thiazolecarboxamide

CAS 302961-09-7C₁₅H₁₉N₃O₃S₂

2-Acetamido-4-methyl-N-(2,4,6-trimethylphenyl)-1,3-thiazole-5-carboxamide chemical structure, C16H19N3O2S, CAS 302959-42-8

2-Acetamido-4-methyl-N-(2,4,6-trimethylphenyl)-1,3-thiazole-5-carboxamide

CAS 302959-42-8C₁₆H₁₉N₃O₂S

N-(2-Chloro-6-methylphenyl)-2-propanamido-1,3-thiazole-5-carboxamide chemical structure, C14H14ClN3O2S, CAS 302961-33-7

N-(2-Chloro-6-methylphenyl)-2-propanamido-1,3-thiazole-5-carboxamide

CAS 302961-33-7C₁₄H₁₄ClN₃O₂S

2-Amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide chemical structure, C11H10ClN3OS, CAS 302964-24-5

2-Amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide

CAS 302964-24-5C₁₁H₁₀ClN₃OS

N-Phenylthiazole-5-carboxamide chemical structure, C10H8N2OS, CAS 90842-21-0

N-Phenylthiazole-5-carboxamide

CAS 90842-21-0C₁₀H₈N₂OS

N-(3-Chlorophenyl)-2,4-dimethyl-1,3-thiazole-5-carboxamide chemical structure, C12H11ClN2OS, CAS 891403-05-7

N-(3-Chlorophenyl)-2,4-dimethyl-1,3-thiazole-5-carboxamide

CAS 891403-05-7C₁₂H₁₁ClN₂OS

N-(4-Bromophenyl)thiazole-5-carboxamide chemical structure, C10H7BrN2OS, CAS 7112-94-9

N-(4-Bromophenyl)thiazole-5-carboxamide

CAS 7112-94-9C₁₀H₇BrN₂OS

N-(3-Bromophenyl)thiazole-5-carboxamide chemical structure, C10H7BrN2OS, CAS 901599-23-3

N-(3-Bromophenyl)thiazole-5-carboxamide

CAS 901599-23-3C₁₀H₇BrN₂OS

N-(4-Bromo-2-fluorophenyl)-4-methylthiazole-5-carboxamide chemical structure, C11H8BrFN2OS, CAS 1016531-41-1

N-(4-Bromo-2-fluorophenyl)-4-methylthiazole-5-carboxamide

CAS 1016531-41-1C₁₁H₈BrFN₂OS

N-(3-Bromophenyl)-4-methylthiazole-5-carboxamide chemical structure, C11H9BrN2OS, CAS 1016708-69-2

N-(3-Bromophenyl)-4-methylthiazole-5-carboxamide

CAS 1016708-69-2C₁₁H₉BrN₂OS

N-(4-Bromophenyl)-4-methylthiazole-5-carboxamide chemical structure, C11H9BrN2OS, CAS 1016775-77-1

N-(4-Bromophenyl)-4-methylthiazole-5-carboxamide

CAS 1016775-77-1C₁₁H₉BrN₂OS

N-(3-Cyanophenyl)-4-methylthiazole-5-carboxamide chemical structure, C12H9N3OS, CAS 1016781-70-6

N-(3-Cyanophenyl)-4-methylthiazole-5-carboxamide

CAS 1016781-70-6C₁₂H₉N₃OS

2,2-Dimethyl-propanoic Acid [2-[[(2-Amino-5-thiazolyl)carbonyl]amino]-3-chlorophenyl]methyl Ester chemical structure, C16H18ClN3O3S, CAS 910297-69-7

2,2-Dimethyl-propanoic Acid [2-[[(2-Amino-5-thiazolyl)carbonyl]amino]-3-chlorophenyl]methyl Ester

CAS 910297-69-7C₁₆H₁₈ClN₃O₃S