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Murcko scaffold

Ring system with 4 rings and 17 atoms

104 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
17
Chemicals
104
With full pages
4
Scaffold SMILES

c1ncc2ncn(C3OCC4OCOC43)c2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ncc2ncn(C3OCC4OCOC43)c2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 104 chemicals

5'-o-Acetyl-2',3'-o-isopropylideneadenosine chemical structure, C15H19N5O5, CAS 15888-38-7
5'-o-Acetyl-2',3'-o-isopropylideneadenosine
CAS 15888-38-7C15H19N5O5
N(6)-Dimethyl-2',3'-isopropylideneadenosine chemical structure, C15H21N5O4, CAS 19083-21-7
N(6)-Dimethyl-2',3'-isopropylideneadenosine
CAS 19083-21-7C15H21N5O4
2',3'-O-Isopropylideneadenosine chemical structure, C13H17N5O4, CAS 362-75-4
2',3'-O-Isopropylideneadenosine
CAS 362-75-4C13H17N5O4
[4-(6-Amino-8-bromopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol chemical structure, C13H16BrN5O4, CAS 13089-45-7
[4-(6-Amino-8-bromopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol
CAS 13089-45-7C13H16BrN5O4
9-[5-o-Acetyl-2,3-o-(1-methylethylidene)pentofuranosyl]-8-bromo-9H-purin-6-amine chemical structure, C15H18BrN5O5, CAS 13089-46-8
9-[5-o-Acetyl-2,3-o-(1-methylethylidene)pentofuranosyl]-8-bromo-9H-purin-6-amine
CAS 13089-46-8C15H18BrN5O5
N-[[4-(6-Aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl]methanesulfonamide chemical structure, C14H20N6O5S, CAS 21950-39-0
N-[[4-(6-Aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl]methanesulfonamide
CAS 21950-39-0C14H20N6O5S
9-[2,3-o-(1-Ethoxyethylidene)pentofuranosyl]-9H-purin-6-amine chemical structure, C14H19N5O5, CAS 42867-77-6
9-[2,3-o-(1-Ethoxyethylidene)pentofuranosyl]-9H-purin-6-amine
CAS 42867-77-6C14H19N5O5
4-(6-Aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carboxylic acid chemical structure, C13H15N5O5, CAS 19234-66-3
4-(6-Aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carboxylic acid
CAS 19234-66-3C13H15N5O5
Methyl 4-(6-aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carboxylate chemical structure, C14H17N5O5, CAS 23754-29-2
Methyl 4-(6-aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carboxylate
CAS 23754-29-2C14H17N5O5
Isopropylidene-adenosine-5-N-methylcarbamide chemical structure, C14H18N6O4, CAS 39491-51-5
Isopropylidene-adenosine-5-N-methylcarbamide
CAS 39491-51-5C14H18N6O4
Ethyl 2-[[4-(6-aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carbonyl]amino]acetate chemical structure, C17H22N6O6, CAS 72758-40-8
Ethyl 2-[[4-(6-aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carbonyl]amino]acetate
CAS 72758-40-8C17H22N6O6
9-[5-s-Ethyl-2,3-o-(1-methylethylidene)-5-thiopentofuranosyluronosyl]-9H-purin-6-amine chemical structure, C15H19N5O4S, CAS 59882-05-2
9-[5-s-Ethyl-2,3-o-(1-methylethylidene)-5-thiopentofuranosyluronosyl]-9H-purin-6-amine
CAS 59882-05-2C15H19N5O4S
9-[2,3-o-(1-Methylethylidene)pentofuranosyl]-6-(methylsulfanyl)-9H-purine chemical structure, C14H18N4O4S, CAS 42021-78-3
9-[2,3-o-(1-Methylethylidene)pentofuranosyl]-6-(methylsulfanyl)-9H-purine
CAS 42021-78-3C14H18N4O4S
9-[6-(Dimethylarsanylsulfanylmethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-amine chemical structure, C15H22AsN5O3S, CAS 84365-03-7
9-[6-(Dimethylarsanylsulfanylmethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-amine
CAS 84365-03-7C15H22AsN5O3S
9H-Purin-6-amine, 9-(5-deoxy-4-C-fluoro-5-iodo-2,3-O-(1-methylethylidene)-alpha-L-lyxofuranosyl)- chemical structure, C13H15FIN5O3, CAS 151725-76-7
9H-Purin-6-amine, 9-(5-deoxy-4-C-fluoro-5-iodo-2,3-O-(1-methylethylidene)-alpha-L-lyxofuranosyl)-
CAS 151725-76-7C13H15FIN5O3
Adenosine, 5'-deoxy-4'-C-fluoro-5'-iodo-2',3'-O-(1-methylethylidene)- chemical structure, C13H15FIN5O3, CAS 151725-74-5
Adenosine, 5'-deoxy-4'-C-fluoro-5'-iodo-2',3'-O-(1-methylethylidene)-
CAS 151725-74-5C13H15FIN5O3
Adenosine, 5'-azido-5'-deoxy-4'-C-fluoro-2',3'-O-(1-methylethylidene)- chemical structure, C13H15FN8O3, CAS 33962-34-4
Adenosine, 5'-azido-5'-deoxy-4'-C-fluoro-2',3'-O-(1-methylethylidene)-
CAS 33962-34-4C13H15FN8O3
9-[(3aR,4R,6S,6aS)-6-(Iodomethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-amine chemical structure, C13H16IN5O3, CAS 30685-66-6
9-[(3aR,4R,6S,6aS)-6-(Iodomethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-amine
CAS 30685-66-6C13H16IN5O3
5'-Azido-5'-deoxy-2',3'-O-isopropylideneadenosine chemical structure, C13H16N8O3, CAS 34245-48-2
5'-Azido-5'-deoxy-2',3'-O-isopropylideneadenosine
CAS 34245-48-2C13H16N8O3
((3aR,4R,6R,6aR)-6-(6-Amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol chemical structure, C13H17N5O4, CAS 21138-44-3
((3aR,4R,6R,6aR)-6-(6-Amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol
CAS 21138-44-3C13H17N5O4
beta-D-Ribofuranurononitrile, 1-(6-amino-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)- chemical structure, C13H14N6O3, CAS 54918-23-9
beta-D-Ribofuranurononitrile, 1-(6-amino-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-
CAS 54918-23-9C13H14N6O3
beta-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-N-2-propenyl- chemical structure, C16H20N6O4, CAS 58048-27-4
beta-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-2,3-O-(1-methylethylidene)-N-2-propenyl-
CAS 58048-27-4C16H20N6O4
RefChem:381493 chemical structure, C13H17N5O5, CAS 175203-92-6
RefChem:381493
CAS 175203-92-6C13H17N5O5
N'-[9-[6-(Hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-yl]-N,N-dimethylmethanimidamide chemical structure, C16H22N6O4, CAS 29706-75-0
N'-[9-[6-(Hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-yl]-N,N-dimethylmethanimidamide
CAS 29706-75-0C16H22N6O4