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Murcko scaffold

2-(Benzylthio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole scaffold

160 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
160
With full pages
25
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN=C1SCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Benzylthio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole page
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN=C1SCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 160 chemicals

2-((2-Fluorobenzyl)thio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C16H15FN2O2S2, CAS 704874-05-5
2-((2-Fluorobenzyl)thio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole
CAS 704874-05-5C16H15FN2O2S2
1-(4-Chlorobenzenesulfonyl)-2-{[(2-fluorophenyl)methyl]sulfanyl}-4,5-dihydro-1H-imidazole chemical structure, C16H14ClFN2O2S2, CAS 704874-07-7
1-(4-Chlorobenzenesulfonyl)-2-{[(2-fluorophenyl)methyl]sulfanyl}-4,5-dihydro-1H-imidazole
CAS 704874-07-7C16H14ClFN2O2S2
2-(Benzylthio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C16H16N2O2S2, CAS 868216-59-5
2-(Benzylthio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-59-5C16H16N2O2S2
2-Benzylsulfanyl-1-(4-methylphenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C17H18N2O2S2, CAS 868216-60-8
2-Benzylsulfanyl-1-(4-methylphenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-60-8C17H18N2O2S2
2-Benzylsulfanyl-1-(4-chlorophenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C16H15ClN2O2S2, CAS 868216-61-9
2-Benzylsulfanyl-1-(4-chlorophenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-61-9C16H15ClN2O2S2
2-(Benzylthio)-1-((4-bromophenyl)sulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C16H15BrN2O2S2, CAS 868216-62-0
2-(Benzylthio)-1-((4-bromophenyl)sulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-62-0C16H15BrN2O2S2
2-(Benzylthio)-1-((4-fluorophenyl)sulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C16H15FN2O2S2, CAS 868216-63-1
2-(Benzylthio)-1-((4-fluorophenyl)sulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-63-1C16H15FN2O2S2
2-Benzylsulfanyl-1-(4-methoxyphenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C17H18N2O3S2, CAS 868216-64-2
2-Benzylsulfanyl-1-(4-methoxyphenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-64-2C17H18N2O3S2
2-(Benzylthio)-1-((4-nitrophenyl)sulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C16H15N3O4S2, CAS 868216-65-3
2-(Benzylthio)-1-((4-nitrophenyl)sulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-65-3C16H15N3O4S2
N-[4-[(2-Benzylsulfanyl-4,5-dihydroimidazol-1-yl)sulfonyl]phenyl]acetamide chemical structure, C18H19N3O3S2, CAS 868216-66-4
N-[4-[(2-Benzylsulfanyl-4,5-dihydroimidazol-1-yl)sulfonyl]phenyl]acetamide
CAS 868216-66-4C18H19N3O3S2
2-((3-Fluorobenzyl)thio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C16H15FN2O2S2, CAS 868216-71-1
2-((3-Fluorobenzyl)thio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-71-1C16H15FN2O2S2
2-((3-Fluorobenzyl)thio)-1-tosyl-4,5-dihydro-1H-imidazole chemical structure, C17H17FN2O2S2, CAS 868216-72-2
2-((3-Fluorobenzyl)thio)-1-tosyl-4,5-dihydro-1H-imidazole
CAS 868216-72-2C17H17FN2O2S2
1-(4-Chlorophenyl)sulfonyl-2-[(3-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazole chemical structure, C16H14ClFN2O2S2, CAS 868216-73-3
1-(4-Chlorophenyl)sulfonyl-2-[(3-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazole
CAS 868216-73-3C16H14ClFN2O2S2
1-(4-Bromophenyl)sulfonyl-2-[(3-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazole chemical structure, C16H14BrFN2O2S2, CAS 868216-74-4
1-(4-Bromophenyl)sulfonyl-2-[(3-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazole
CAS 868216-74-4C16H14BrFN2O2S2
2-[(3-Fluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C16H14F2N2O2S2, CAS 868216-75-5
2-[(3-Fluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-75-5C16H14F2N2O2S2
2-[(3-Fluorophenyl)methylsulfanyl]-1-(4-methoxyphenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C17H17FN2O3S2, CAS 868216-76-6
2-[(3-Fluorophenyl)methylsulfanyl]-1-(4-methoxyphenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-76-6C17H17FN2O3S2
2-[(3-Fluorophenyl)methylsulfanyl]-1-(4-nitrophenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C16H14FN3O4S2, CAS 868216-77-7
2-[(3-Fluorophenyl)methylsulfanyl]-1-(4-nitrophenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-77-7C16H14FN3O4S2
N-[4-[[2-[(3-Fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]sulfonyl]phenyl]acetamide chemical structure, C18H18FN3O3S2, CAS 868216-78-8
N-[4-[[2-[(3-Fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]sulfonyl]phenyl]acetamide
CAS 868216-78-8C18H18FN3O3S2
2-((4-Fluorobenzyl)thio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C16H15FN2O2S2, CAS 868216-83-5
2-((4-Fluorobenzyl)thio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-83-5C16H15FN2O2S2
2-((4-Fluorobenzyl)thio)-1-tosyl-4,5-dihydro-1H-imidazole chemical structure, C17H17FN2O2S2, CAS 868216-84-6
2-((4-Fluorobenzyl)thio)-1-tosyl-4,5-dihydro-1H-imidazole
CAS 868216-84-6C17H17FN2O2S2
1-(4-Chlorophenyl)sulfonyl-2-[(4-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazole chemical structure, C16H14ClFN2O2S2, CAS 868216-85-7
1-(4-Chlorophenyl)sulfonyl-2-[(4-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazole
CAS 868216-85-7C16H14ClFN2O2S2
1-(4-Bromophenyl)sulfonyl-2-[(4-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazole chemical structure, C16H14BrFN2O2S2, CAS 868216-86-8
1-(4-Bromophenyl)sulfonyl-2-[(4-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazole
CAS 868216-86-8C16H14BrFN2O2S2
2-[(4-Fluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C16H14F2N2O2S2, CAS 868216-87-9
2-[(4-Fluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-87-9C16H14F2N2O2S2
2-[(4-Fluorophenyl)methylsulfanyl]-1-(4-methoxyphenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C17H17FN2O3S2, CAS 868216-88-0
2-[(4-Fluorophenyl)methylsulfanyl]-1-(4-methoxyphenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-88-0C17H17FN2O3S2