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Murcko scaffold

(2Z)-2-(Phenylimino)-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide scaffold

87 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 25
Chemicals: 87
With full pages: 1

Scaffold SMILES

O=C(Nc1nccs1)c1cc2ccccc2oc1=Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the (2Z)-2-(Phenylimino)-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide page

Murcko scaffold O=C(Nc1nccs1)c1cc2ccccc2oc1=Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 87 chemicals

(2Z)-2-[(3,4-Dimethoxyphenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C21H17N3O4S, CAS 478481-13-9

(2Z)-2-[(3,4-Dimethoxyphenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 478481-13-9C₂₁H₁₇N₃O₄S

(2Z)-2-[(3,4-Dimethoxyphenyl)imino]-8-methoxy-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C22H19N3O5S, CAS 478481-38-8

(2Z)-2-[(3,4-Dimethoxyphenyl)imino]-8-methoxy-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 478481-38-8C₂₂H₁₉N₃O₅S

(2Z)-6-Bromo-2-[(3-chlorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H11BrClN3O2S, CAS 688767-76-2

(2Z)-6-Bromo-2-[(3-chlorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 688767-76-2C₁₉H₁₁BrClN₃O₂S

(2Z)-6-Bromo-2-[(4-chlorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H11BrClN3O2S, CAS 688767-77-3

(2Z)-6-Bromo-2-[(4-chlorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 688767-77-3C₁₉H₁₁BrClN₃O₂S

(2Z)-2-[(3-Chlorophenyl)imino]-8-methoxy-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C20H14ClN3O3S, CAS 688767-93-3

(2Z)-2-[(3-Chlorophenyl)imino]-8-methoxy-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 688767-93-3C₂₀H₁₄ClN₃O₃S

(2Z)-8-Methoxy-N-(1,3-thiazol-2-yl)-2-{[3-(trifluoromethyl)phenyl]imino}-2H-chromene-3-carboxamide chemical structure, C21H14F3N3O3S, CAS 688768-01-6

(2Z)-8-Methoxy-N-(1,3-thiazol-2-yl)-2-{[3-(trifluoromethyl)phenyl]imino}-2H-chromene-3-carboxamide

CAS 688768-01-6C₂₁H₁₄F₃N₃O₃S

(2Z)-2-(Phenylimino)-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H13N3O2S, CAS 688767-50-2

(2Z)-2-(Phenylimino)-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 688767-50-2C₁₉H₁₃N₃O₂S

(2Z)-2-[(2-Methylphenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C20H15N3O2S, CAS 688767-51-3

(2Z)-2-[(2-Methylphenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 688767-51-3C₂₀H₁₅N₃O₂S

(2Z)-2-[(2-Methoxyphenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C20H15N3O3S, CAS 688767-54-6

(2Z)-2-[(2-Methoxyphenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 688767-54-6C₂₀H₁₅N₃O₃S

(2Z)-2-[(3-Chlorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H12ClN3O2S, CAS 688767-56-8

(2Z)-2-[(3-Chlorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 688767-56-8C₁₉H₁₂ClN₃O₂S

(2Z)-2-[(4-Chlorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H12ClN3O2S, CAS 688767-57-9

(2Z)-2-[(4-Chlorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 688767-57-9C₁₉H₁₂ClN₃O₂S

(2Z)-N-(1,3-Thiazol-2-yl)-2-{[3-(trifluoromethyl)phenyl]imino}-2H-chromene-3-carboxamide chemical structure, C20H12F3N3O2S, CAS 688767-63-7

(2Z)-N-(1,3-Thiazol-2-yl)-2-{[3-(trifluoromethyl)phenyl]imino}-2H-chromene-3-carboxamide

CAS 688767-63-7C₂₀H₁₂F₃N₃O₂S

(2Z)-2-[(4-Carbamoylphenyl)imino]-6-chloro-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C20H13ClN4O3S, CAS 1327181-35-0

(2Z)-2-[(4-Carbamoylphenyl)imino]-6-chloro-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 1327181-35-0C₂₀H₁₃ClN₄O₃S

Methyl 3-{[(2Z)-6-chloro-3-[(1,3-thiazol-2-yl)carbamoyl]-2H-chromen-2-ylidene]amino}benzoate chemical structure, C21H14ClN3O4S, CAS 1327182-33-1

Methyl 3-{[(2Z)-6-chloro-3-[(1,3-thiazol-2-yl)carbamoyl]-2H-chromen-2-ylidene]amino}benzoate

CAS 1327182-33-1C₂₁H₁₄ClN₃O₄S

Ethyl 3-{[(2Z)-6-chloro-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate chemical structure, C22H16ClN3O4S, CAS 1327197-14-7

Ethyl 3-{[(2Z)-6-chloro-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate

CAS 1327197-14-7C₂₂H₁₆ClN₃O₄S

(2Z)-6-Chloro-2-[(2,4-difluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H10ClF2N3O2S, CAS 1327186-98-0

(2Z)-6-Chloro-2-[(2,4-difluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 1327186-98-0C₁₉H₁₀ClF₂N₃O₂S

(2Z)-6-Chloro-2-[(2,5-difluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H10ClF2N3O2S, CAS 1327169-83-4

(2Z)-6-Chloro-2-[(2,5-difluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 1327169-83-4C₁₉H₁₀ClF₂N₃O₂S

(2Z)-6-Chloro-2-[(3,4-difluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H10ClF2N3O2S, CAS 1327176-21-5

(2Z)-6-Chloro-2-[(3,4-difluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 1327176-21-5C₁₉H₁₀ClF₂N₃O₂S

Methyl 3-{[(2Z)-6-bromo-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate chemical structure, C21H14BrN3O4S, CAS 1327170-90-0

Methyl 3-{[(2Z)-6-bromo-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate

CAS 1327170-90-0C₂₁H₁₄BrN₃O₄S

Ethyl 3-{[(2Z)-6-bromo-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate chemical structure, C22H16BrN3O4S, CAS 1327183-03-8

Ethyl 3-{[(2Z)-6-bromo-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate

CAS 1327183-03-8C₂₂H₁₆BrN₃O₄S

Methyl 4-{[(2Z)-6-bromo-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate chemical structure, C21H14BrN3O4S, CAS 1327176-33-9

Methyl 4-{[(2Z)-6-bromo-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate

CAS 1327176-33-9C₂₁H₁₄BrN₃O₄S

Ethyl 4-{[(2Z)-6-bromo-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate chemical structure, C22H16BrN3O4S, CAS 1327172-94-0

Ethyl 4-{[(2Z)-6-bromo-3-(1,3-thiazol-2-ylcarbamoyl)-2H-chromen-2-ylidene]amino}benzoate

CAS 1327172-94-0C₂₂H₁₆BrN₃O₄S

(2Z)-6-Bromo-2-[(2-fluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H11BrFN3O2S, CAS 1327187-18-7

(2Z)-6-Bromo-2-[(2-fluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 1327187-18-7C₁₉H₁₁BrFN₃O₂S

(2Z)-6-Bromo-2-[(2,4-difluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide chemical structure, C19H10BrF2N3O2S, CAS 1327169-45-8

(2Z)-6-Bromo-2-[(2,4-difluorophenyl)imino]-N-(1,3-thiazol-2-yl)-2H-chromene-3-carboxamide

CAS 1327169-45-8C₁₉H₁₀BrF₂N₃O₂S