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Murcko scaffold

Ring system with 3 rings and 20 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
19
With full pages
1
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(N2CCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc(N2CCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-(3-Methoxyphenyl)-3-nitro-4-(pyrrolidin-1-yl)benzamide chemical structure, C18H19N3O4, CAS 451506-83-5
N-(3-Methoxyphenyl)-3-nitro-4-(pyrrolidin-1-yl)benzamide
CAS 451506-83-5C18H19N3O4
N-(3-Bromophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C17H16BrN3O3, CAS 638143-91-6
N-(3-Bromophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 638143-91-6C17H16BrN3O3
N-(2,4-Dichlorophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C17H15Cl2N3O3, CAS 638144-21-5
N-(2,4-Dichlorophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 638144-21-5C17H15Cl2N3O3
N-(3-Chloro-4-methylphenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C18H18ClN3O3, CAS 638144-04-4
N-(3-Chloro-4-methylphenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 638144-04-4C18H18ClN3O3
N-(2-Bromophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C17H16BrN3O3, CAS 380470-89-3
N-(2-Bromophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 380470-89-3C17H16BrN3O3
Methyl 4-({[3-nitro-4-(pyrrolidin-1-yl)phenyl]carbonyl}amino)benzoate chemical structure, C19H19N3O5, CAS 638144-45-3
Methyl 4-({[3-nitro-4-(pyrrolidin-1-yl)phenyl]carbonyl}amino)benzoate
CAS 638144-45-3C19H19N3O5
N-(2-Chloro-4-iodophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C17H15ClIN3O3, CAS 638144-00-0
N-(2-Chloro-4-iodophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 638144-00-0C17H15ClIN3O3
N-(2-Fluoro-4-iodophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C17H15FIN3O3, CAS 638144-29-3
N-(2-Fluoro-4-iodophenyl)-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 638144-29-3C17H15FIN3O3
Dimethyl 5-({[3-nitro-4-(pyrrolidin-1-yl)phenyl]carbonyl}amino)benzene-1,3-dicarboxylate chemical structure, C21H21N3O7, CAS 638144-44-2
Dimethyl 5-({[3-nitro-4-(pyrrolidin-1-yl)phenyl]carbonyl}amino)benzene-1,3-dicarboxylate
CAS 638144-44-2C21H21N3O7
N-[5-Chloro-2-(trifluoromethyl)phenyl]-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C18H15ClF3N3O3, CAS 578736-61-5
N-[5-Chloro-2-(trifluoromethyl)phenyl]-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 578736-61-5C18H15ClF3N3O3
N-[2-Chloro-5-(trifluoromethyl)phenyl]-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C18H15ClF3N3O3, CAS 836662-29-4
N-[2-Chloro-5-(trifluoromethyl)phenyl]-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 836662-29-4C18H15ClF3N3O3
3-Nitro-4-pyrrolidin-1-yl-N-(2,4,5-trichlorophenyl)benzamide chemical structure, C17H14Cl3N3O3, CAS 767316-28-9
3-Nitro-4-pyrrolidin-1-yl-N-(2,4,5-trichlorophenyl)benzamide
CAS 767316-28-9C17H14Cl3N3O3
3-Nitro-N-phenyl-4-pyrrolidin-1-ylbenzamide chemical structure, C17H17N3O3, CAS 771513-62-3
3-Nitro-N-phenyl-4-pyrrolidin-1-ylbenzamide
CAS 771513-62-3C17H17N3O3
3-Nitro-N-[4-(propanoylamino)phenyl]-4-pyrrolidin-1-ylbenzamide chemical structure, C20H22N4O4, CAS 638145-84-3
3-Nitro-N-[4-(propanoylamino)phenyl]-4-pyrrolidin-1-ylbenzamide
CAS 638145-84-3C20H22N4O4
N-[3-Methoxy-4-(pentanoylamino)phenyl]-3-nitro-4-pyrrolidin-1-ylbenzamide chemical structure, C23H28N4O5, CAS 831250-22-7
N-[3-Methoxy-4-(pentanoylamino)phenyl]-3-nitro-4-pyrrolidin-1-ylbenzamide
CAS 831250-22-7C23H28N4O5
N-(4-Fluorophenyl)-4-(pyrrolidin-1-yl)benzamide chemical structure, C17H17FN2O, CAS 931372-03-1
N-(4-Fluorophenyl)-4-(pyrrolidin-1-yl)benzamide
CAS 931372-03-1C17H17FN2O
Epptb chemical structure, C20H21F3N2O2, CAS 1110781-88-8
Epptb
CAS 1110781-88-8C20H21F3N2O2
N-(3-Chloro-4-fluorophenyl)-4-(3-methoxypyrrolidin-1-yl)benzamide chemical structure, C18H18ClFN2O2, CAS 1797139-91-3
N-(3-Chloro-4-fluorophenyl)-4-(3-methoxypyrrolidin-1-yl)benzamide
CAS 1797139-91-3C18H18ClFN2O2
N-(3-Chloro-4-methoxyphenyl)-4-(3-methoxypyrrolidin-1-yl)benzamide chemical structure, C19H21ClN2O3, CAS 1797873-31-4
N-(3-Chloro-4-methoxyphenyl)-4-(3-methoxypyrrolidin-1-yl)benzamide
CAS 1797873-31-4C19H21ClN2O3