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Murcko scaffold

1,5,6,7-Tetrahydropyrrolo[3,4-d]pyrimidin-4-one scaffold

26 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
26
With full pages
5
Scaffold SMILES

O=c1[nH]cnc2c1CNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,5,6,7-Tetrahydropyrrolo[3,4-d]pyrimidin-4-one page
Murcko scaffold O=c1[nH]cnc2c1CNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2,3-Dimethyl-3,5,6,7-tetrahydro-4H-pyrrolo(3,4-d)pyrimidin-4-one dihydrochloride hydrate chemical structure, C8H15Cl2N3O2, CAS 1243250-20-5
2,3-Dimethyl-3,5,6,7-tetrahydro-4H-pyrrolo(3,4-d)pyrimidin-4-one dihydrochloride hydrate
CAS 1243250-20-5C8H15Cl2N3O2
1,5,6,7-Tetrahydropyrrolo[3,4-d]pyrimidin-4-one chemical structure, C6H7N3O, CAS 802568-50-9
1,5,6,7-Tetrahydropyrrolo[3,4-d]pyrimidin-4-one
CAS 802568-50-9C6H7N3O
6-Acetyl-7-methyl-1,5,6,7-tetrahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one chemical structure, C9H11N3O2, CAS 15199-07-2
6-Acetyl-7-methyl-1,5,6,7-tetrahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one
CAS 15199-07-2C9H11N3O2
6-Acetyl-1,5,6,7-tetrahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one chemical structure, C8H9N3O2, CAS 15199-05-0
6-Acetyl-1,5,6,7-tetrahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one
CAS 15199-05-0C8H9N3O2
3H,4H,5H,6H,7H-Pyrrolo[3,4-d]pyrimidin-4-one hydrochloride chemical structure, C6H8ClN3O, CAS 15199-08-3
3H,4H,5H,6H,7H-Pyrrolo[3,4-d]pyrimidin-4-one hydrochloride
CAS 15199-08-3C6H8ClN3O
tert-Butyl 4-oxo-3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidine-6-carboxylate chemical structure, C11H15N3O3, CAS 1229455-14-4
tert-Butyl 4-oxo-3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidine-6-carboxylate
CAS 1229455-14-4C11H15N3O3
2-Amino-1H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-one chemical structure, C6H8N4O, CAS 802280-21-3
2-Amino-1H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-one
CAS 802280-21-3C6H8N4O
tert-Butyl 2-amino-4-hydroxy-5H,6H,7H-pyrrolo[3,4-d]pyrimidine-6-carboxylate chemical structure, C11H16N4O3, CAS 1263284-35-0
tert-Butyl 2-amino-4-hydroxy-5H,6H,7H-pyrrolo[3,4-d]pyrimidine-6-carboxylate
CAS 1263284-35-0C11H16N4O3
tert-Butyl 2-methyl-4-oxo-3,4,5,7-tetrahydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate chemical structure, C12H17N3O3, CAS 1073477-40-3
tert-Butyl 2-methyl-4-oxo-3,4,5,7-tetrahydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate
CAS 1073477-40-3C12H17N3O3
Ethyl 2-amino-4-oxo-5,7-dihydro-3H-pyrrolo[3,4-d]pyrimidine-6(4H)-carboxylate chemical structure, C9H12N4O3, CAS 1046861-16-8
Ethyl 2-amino-4-oxo-5,7-dihydro-3H-pyrrolo[3,4-d]pyrimidine-6(4H)-carboxylate
CAS 1046861-16-8C9H12N4O3
2-Methoxy-6,7-dihydro-5H-pyrrolo-[3,4-d]pyrimidin-4-ol chemical structure, C7H9N3O2, CAS 1220030-96-5
2-Methoxy-6,7-dihydro-5H-pyrrolo-[3,4-d]pyrimidin-4-ol
CAS 1220030-96-5C7H9N3O2
2-Methyl-5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-ol chemical structure, C7H9N3O, CAS 1220030-34-1
2-Methyl-5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-ol
CAS 1220030-34-1C7H9N3O
2-Ethyl-6,7-dihydro-3H-pyrrolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C8H11N3O, CAS 1220030-37-4
2-Ethyl-6,7-dihydro-3H-pyrrolo[3,4-d]pyrimidin-4(5H)-one
CAS 1220030-37-4C8H11N3O
2-(tert-Butyl)-6,7-dihydro-3H-pyrrolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C10H15N3O, CAS 1220027-21-3
2-(tert-Butyl)-6,7-dihydro-3H-pyrrolo[3,4-d]pyrimidin-4(5H)-one
CAS 1220027-21-3C10H15N3O
2-Isopropyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-ol chemical structure, C9H13N3O, CAS 1220035-92-6
2-Isopropyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-ol
CAS 1220035-92-6C9H13N3O
2-Propyl-6,7-dihydro-5H-pyrrolo-[3,4-d]pyrimidin-4-ol chemical structure, C9H13N3O, CAS 1220035-95-9
2-Propyl-6,7-dihydro-5H-pyrrolo-[3,4-d]pyrimidin-4-ol
CAS 1220035-95-9C9H13N3O
5-Methyl-4-oxo-3,4,5,7-tetrahydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester chemical structure, C12H17N3O3, CAS 1229455-55-3
5-Methyl-4-oxo-3,4,5,7-tetrahydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
CAS 1229455-55-3C12H17N3O3
2-Methyl-3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-one hydrochloride chemical structure, C7H10ClN3O, CAS 1956309-51-5
2-Methyl-3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-one hydrochloride
CAS 1956309-51-5C7H10ClN3O
2-(Butan-2-yl)-5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-ol chemical structure, C10H15N3O, CAS 1592955-58-2
2-(Butan-2-yl)-5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-ol
CAS 1592955-58-2C10H15N3O
2-Methyl-5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-ol dihydrochloride chemical structure, C7H11Cl2N3O, CAS 2044714-12-5
2-Methyl-5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-ol dihydrochloride
CAS 2044714-12-5C7H11Cl2N3O
2-Methyl-6-prop-2-enoyl-5,7-dihydro-3H-pyrrolo[3,4-d]pyrimidin-4-one chemical structure, C10H11N3O2, CAS 2249242-40-6
2-Methyl-6-prop-2-enoyl-5,7-dihydro-3H-pyrrolo[3,4-d]pyrimidin-4-one
CAS 2249242-40-6C10H11N3O2
tert-Butyl 2-(methylthio)-4-oxo-1,4,5,7-tetrahydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate chemical structure, C12H17N3O3S, CAS 2384899-62-9
tert-Butyl 2-(methylthio)-4-oxo-1,4,5,7-tetrahydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate
CAS 2384899-62-9C12H17N3O3S
2-Methylsulfanyl-6-(2,2,2-trifluoroacetyl)-5,7-dihydro-1H-pyrrolo[3,4-d]pyrimidin-4-one chemical structure, C9H8F3N3O2S, CAS 2736597-79-6
2-Methylsulfanyl-6-(2,2,2-trifluoroacetyl)-5,7-dihydro-1H-pyrrolo[3,4-d]pyrimidin-4-one
CAS 2736597-79-6C9H8F3N3O2S
2-(Trichloromethyl)-3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-one chemical structure, C7H6Cl3N3O, CAS 2137979-06-5
2-(Trichloromethyl)-3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyrimidin-4-one
CAS 2137979-06-5C7H6Cl3N3O