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Murcko scaffold

Ring system with 2 rings and 11 atoms

140 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
140
With full pages
5
Scaffold SMILES

c1csc(Cn2cccn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(Cn2cccn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 140 chemicals

1-[(5-Bromothiophen-2-yl)methyl]-1H-pyrazol-5-amine chemical structure, C8H8BrN3S, CAS 926257-64-9
1-[(5-Bromothiophen-2-yl)methyl]-1H-pyrazol-5-amine
CAS 926257-64-9C8H8BrN3S
1-(Thiophen-2-ylmethyl)-1H-pyrazol-5-amine chemical structure, C8H9N3S, CAS 4394-26-7
1-(Thiophen-2-ylmethyl)-1H-pyrazol-5-amine
CAS 4394-26-7C8H9N3S
1-((4-Bromothiophen-2-yl)methyl)-1H-pyrazol-5-amine chemical structure, C8H8BrN3S, CAS 956453-87-5
1-((4-Bromothiophen-2-yl)methyl)-1H-pyrazol-5-amine
CAS 956453-87-5C8H8BrN3S
1-[(3-Methylthiophen-2-yl)methyl]-1H-pyrazol-5-amine chemical structure, C9H11N3S, CAS 956387-06-7
1-[(3-Methylthiophen-2-yl)methyl]-1H-pyrazol-5-amine
CAS 956387-06-7C9H11N3S
1-(1-Thien-2-ylethyl)-1H-pyrazol-5-amine chemical structure, C9H11N3S, CAS 956949-76-1
1-(1-Thien-2-ylethyl)-1H-pyrazol-5-amine
CAS 956949-76-1C9H11N3S
3-Methyl-1-(2-thienylmethyl)-1H-pyrazol-5-amine chemical structure, C9H11N3S, CAS 4394-28-9
3-Methyl-1-(2-thienylmethyl)-1H-pyrazol-5-amine
CAS 4394-28-9C9H11N3S
5-Methyl-2-(1-thiophen-2-yl-ethyl)-2H-pyrazol-3-ylamine chemical structure, C10H13N3S, CAS 957483-06-6
5-Methyl-2-(1-thiophen-2-yl-ethyl)-2H-pyrazol-3-ylamine
CAS 957483-06-6C10H13N3S
1-[(5-Methylthiophen-2-yl)methyl]-1H-pyrazol-5-amine chemical structure, C9H11N3S, CAS 956507-85-0
1-[(5-Methylthiophen-2-yl)methyl]-1H-pyrazol-5-amine
CAS 956507-85-0C9H11N3S
5-(1H-Pyrazol-1-ylmethyl)thiophene-2-carboxylic acid chemical structure, C9H8N2O2S, CAS 1006334-18-4
5-(1H-Pyrazol-1-ylmethyl)thiophene-2-carboxylic acid
CAS 1006334-18-4C9H8N2O2S
5-[(4-Chloro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid chemical structure, C9H7ClN2O2S, CAS 1006455-24-8
5-[(4-Chloro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid
CAS 1006455-24-8C9H7ClN2O2S
5-[(4-Bromo-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid chemical structure, C9H7BrN2O2S, CAS 1006485-87-5
5-[(4-Bromo-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid
CAS 1006485-87-5C9H7BrN2O2S
5-[(4-Nitro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid chemical structure, C9H7N3O4S, CAS 1006457-69-7
5-[(4-Nitro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid
CAS 1006457-69-7C9H7N3O4S
5-((3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)methyl)thiophene-2-carboxylic acid chemical structure, C11H11N3O4S, CAS 1006955-28-7
5-((3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)methyl)thiophene-2-carboxylic acid
CAS 1006955-28-7C11H11N3O4S
5-[(3-Nitro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid chemical structure, C9H7N3O4S, CAS 1006457-74-4
5-[(3-Nitro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid
CAS 1006457-74-4C9H7N3O4S
5-[(4-Chloro-3-nitro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid chemical structure, C9H6ClN3O4S, CAS 1006955-33-4
5-[(4-Chloro-3-nitro-1H-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid
CAS 1006955-33-4C9H6ClN3O4S
1-[(5-Chlorothiophen-2-yl)methyl]-1H-pyrazol-4-amine chemical structure, C8H8ClN3S, CAS 1152867-67-8
1-[(5-Chlorothiophen-2-yl)methyl]-1H-pyrazol-4-amine
CAS 1152867-67-8C8H8ClN3S
1-[(Thiophen-2-yl)methyl]-1H-pyrazol-4-amine chemical structure, C8H9N3S, CAS 1152853-48-9
1-[(Thiophen-2-yl)methyl]-1H-pyrazol-4-amine
CAS 1152853-48-9C8H9N3S
1-((5-Bromothiophen-2-yl)methyl)-1H-pyrazol-4-amine chemical structure, C8H8BrN3S, CAS 1152867-73-6
1-((5-Bromothiophen-2-yl)methyl)-1H-pyrazol-4-amine
CAS 1152867-73-6C8H8BrN3S
1-((5-Ethylthiophen-2-yl)methyl)-1H-pyrazol-4-amine chemical structure, C10H13N3S, CAS 1152853-63-8
1-((5-Ethylthiophen-2-yl)methyl)-1H-pyrazol-4-amine
CAS 1152853-63-8C10H13N3S
1-((5-Chlorothiophen-2-yl)methyl)-3,5-dimethyl-1H-pyrazol-4-amine chemical structure, C10H12ClN3S, CAS 1152951-78-4
1-((5-Chlorothiophen-2-yl)methyl)-3,5-dimethyl-1H-pyrazol-4-amine
CAS 1152951-78-4C10H12ClN3S
3,5-Dimethyl-1-[(thiophen-2-yl)methyl]-1H-pyrazol-4-amine chemical structure, C10H13N3S, CAS 1152839-79-6
3,5-Dimethyl-1-[(thiophen-2-yl)methyl]-1H-pyrazol-4-amine
CAS 1152839-79-6C10H13N3S
1-[(5-Bromothiophen-2-yl)methyl]-3,5-dimethyl-1H-pyrazol-4-amine chemical structure, C10H12BrN3S, CAS 1152840-03-3
1-[(5-Bromothiophen-2-yl)methyl]-3,5-dimethyl-1H-pyrazol-4-amine
CAS 1152840-03-3C10H12BrN3S
1-[(5-Chlorothiophen-2-yl)methyl]-1H-pyrazol-5-amine chemical structure, C8H8ClN3S, CAS 1152588-32-3
1-[(5-Chlorothiophen-2-yl)methyl]-1H-pyrazol-5-amine
CAS 1152588-32-3C8H8ClN3S
1-[(5-Chlorothiophen-2-yl)methyl]-1H-pyrazole-4-carboxylic acid chemical structure, C9H7ClN2O2S, CAS 1154881-82-9
1-[(5-Chlorothiophen-2-yl)methyl]-1H-pyrazole-4-carboxylic acid
CAS 1154881-82-9C9H7ClN2O2S