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Murcko scaffold

Ring system with 4 rings and 24 atoms

13 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 13
With full pages: 2

Scaffold SMILES

c1ccc(NC(c2ccc3cccnc3c2)c2ccccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(NC(c2ccc3cccnc3c2)c2ccccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Methyl 2-(((8-hydroxy-7-quinolinyl)(2-pyridinyl)methyl)amino)benzoate chemical structure, C23H19N3O3, CAS 80003-76-5

Methyl 2-(((8-hydroxy-7-quinolinyl)(2-pyridinyl)methyl)amino)benzoate

CAS 80003-76-5C₂₃H₁₉N₃O₃

7-[(Phenylamino)(pyridin-2-yl)methyl]quinolin-8-ol chemical structure, C21H17N3O, CAS 33391-74-1

7-[(Phenylamino)(pyridin-2-yl)methyl]quinolin-8-ol

CAS 33391-74-1C₂₁H₁₇N₃O

7-(((4-(Difluoromethoxy)phenyl)amino)(pyridin-2-yl)methyl)quinolin-8-ol chemical structure, C22H17F2N3O2, CAS 385786-50-5

7-(((4-(Difluoromethoxy)phenyl)amino)(pyridin-2-yl)methyl)quinolin-8-ol

CAS 385786-50-5C₂₂H₁₇F₂N₃O₂

7-(Pyridin-2-yl((3-(trifluoromethyl)phenyl)amino)methyl)quinolin-8-ol chemical structure, C22H16F3N3O, CAS 308294-75-9

7-(Pyridin-2-yl((3-(trifluoromethyl)phenyl)amino)methyl)quinolin-8-ol

CAS 308294-75-9C₂₂H₁₆F₃N₃O

7-{[(4-Nitrophenyl)amino](pyridin-2-yl)methyl}quinolin-8-ol chemical structure, C21H16N4O3, CAS 307341-91-9

7-{[(4-Nitrophenyl)amino](pyridin-2-yl)methyl}quinolin-8-ol

CAS 307341-91-9C₂₁H₁₆N₄O₃

7-(((4-Chlorophenyl)amino)(pyridin-2-yl)methyl)quinolin-8-ol chemical structure, C21H16ClN3O, CAS 33495-41-9

7-(((4-Chlorophenyl)amino)(pyridin-2-yl)methyl)quinolin-8-ol

CAS 33495-41-9C₂₁H₁₆ClN₃O

7-{[(4-Methoxyphenyl)amino](pyridin-2-yl)methyl}quinolin-8-ol chemical structure, C22H19N3O2, CAS 33495-37-3

7-{[(4-Methoxyphenyl)amino](pyridin-2-yl)methyl}quinolin-8-ol

CAS 33495-37-3C₂₂H₁₉N₃O₂

N-(4-{[(8-Hydroxyquinolin-7-yl)(pyridin-2-yl)methyl]amino}phenyl)acetamide chemical structure, C23H20N4O2, CAS 622791-81-5

N-(4-{[(8-Hydroxyquinolin-7-yl)(pyridin-2-yl)methyl]amino}phenyl)acetamide

CAS 622791-81-5C₂₃H₂₀N₄O₂

7-{[(3-Methoxyphenyl)amino](pyridin-2-yl)methyl}quinolin-8-ol chemical structure, C22H19N3O2, CAS 315240-23-4

7-{[(3-Methoxyphenyl)amino](pyridin-2-yl)methyl}quinolin-8-ol

CAS 315240-23-4C₂₂H₁₉N₃O₂

7-(((4-Ethoxyphenyl)amino)(pyridin-2-yl)methyl)quinolin-8-ol chemical structure, C23H21N3O2, CAS 33495-39-5

7-(((4-Ethoxyphenyl)amino)(pyridin-2-yl)methyl)quinolin-8-ol

CAS 33495-39-5C₂₃H₂₁N₃O₂

7-{[(3-Chlorophenyl)amino](pyridin-2-yl)methyl}-2-methylquinolin-8-ol chemical structure, C22H18ClN3O, CAS 385786-17-4

7-{[(3-Chlorophenyl)amino](pyridin-2-yl)methyl}-2-methylquinolin-8-ol

CAS 385786-17-4C₂₂H₁₈ClN₃O

7-[[(2-Methylphenyl)amino]-2-pyridinylmethyl]-8-quinolinol chemical structure, C22H19N3O, CAS 33495-34-0

7-[[(2-Methylphenyl)amino]-2-pyridinylmethyl]-8-quinolinol

CAS 33495-34-0C₂₂H₁₉N₃O

5-Chloro-7-((phenylamino)(pyridin-2-yl)methyl)quinolin-8-ol chemical structure, C21H16ClN3O, CAS 1239748-09-4

5-Chloro-7-((phenylamino)(pyridin-2-yl)methyl)quinolin-8-ol

CAS 1239748-09-4C₂₁H₁₆ClN₃O