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Murcko scaffold

Ring system with 4 rings and 24 atoms

75 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 75
With full pages: 31

Scaffold SMILES

c1ccc(C(Nc2ccccn2)c2ccc3cccnc3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(C(Nc2ccccn2)c2ccc3cccnc3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 75 chemicals

7-[alpha-[(4-Methyl-2-pyridyl)amino]benzyl]-8-quinolinol chemical structure, C22H19N3O, CAS 5335-98-8

7-[alpha-[(4-Methyl-2-pyridyl)amino]benzyl]-8-quinolinol

CAS 5335-98-8C₂₂H₁₉N₃O

7-{Phenyl[(pyridin-2-yl)amino]methyl}quinolin-8-ol chemical structure, C21H17N3O, CAS 304685-32-3

7-{Phenyl[(pyridin-2-yl)amino]methyl}quinolin-8-ol

CAS 304685-32-3C₂₁H₁₇N₃O

7-[[(6-Methyl-2-pyridinyl)amino](phenyl)methyl]-8-quinolinol chemical structure, C22H19N3O, CAS 353788-93-9

7-[[(6-Methyl-2-pyridinyl)amino](phenyl)methyl]-8-quinolinol

CAS 353788-93-9C₂₂H₁₉N₃O

7-[(4-Ethylphenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol chemical structure, C24H23N3O, CAS 6372-37-8

7-[(4-Ethylphenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol

CAS 6372-37-8C₂₄H₂₃N₃O

7-[(4-Methylphenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol chemical structure, C22H19N3O, CAS 352691-35-1

7-[(4-Methylphenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol

CAS 352691-35-1C₂₂H₁₉N₃O

7-[(4-Propan-2-yloxyphenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol chemical structure, C24H23N3O2, CAS 354778-12-4

7-[(4-Propan-2-yloxyphenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol

CAS 354778-12-4C₂₄H₂₃N₃O₂

7-[(2,3-Dimethoxyphenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol chemical structure, C24H23N3O3, CAS 353519-28-5

7-[(2,3-Dimethoxyphenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol

CAS 353519-28-5C₂₄H₂₃N₃O₃

7-[(4-Chlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol chemical structure, C21H16ClN3O, CAS 315234-77-6

7-[(4-Chlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol

CAS 315234-77-6C₂₁H₁₆ClN₃O

7-[(2,3-Dichlorophenyl)(pyridin-2-ylamino)methyl]quinolin-8-ol chemical structure, C21H15Cl2N3O, CAS 352693-80-2

7-[(2,3-Dichlorophenyl)(pyridin-2-ylamino)methyl]quinolin-8-ol

CAS 352693-80-2C₂₁H₁₅Cl₂N₃O

7-[(4-Prop-2-enoxyphenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol chemical structure, C24H21N3O2, CAS 6375-12-8

7-[(4-Prop-2-enoxyphenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol

CAS 6375-12-8C₂₄H₂₁N₃O₂

7-[(4-Ethoxy-3-methylphenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol chemical structure, C25H25N3O2, CAS 353519-63-8

7-[(4-Ethoxy-3-methylphenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol

CAS 353519-63-8C₂₅H₂₅N₃O₂

7-[(4-Methylphenyl)-[(6-methylpyridin-2-yl)amino]methyl]quinolin-8-ol chemical structure, C23H21N3O, CAS 353773-66-7

7-[(4-Methylphenyl)-[(6-methylpyridin-2-yl)amino]methyl]quinolin-8-ol

CAS 353773-66-7C₂₃H₂₁N₃O

7-[(4-Fluorophenyl)-[(6-methylpyridin-2-yl)amino]methyl]quinolin-8-ol chemical structure, C22H18FN3O, CAS 355000-80-5

7-[(4-Fluorophenyl)-[(6-methylpyridin-2-yl)amino]methyl]quinolin-8-ol

CAS 355000-80-5C₂₂H₁₈FN₃O

7-((3,4-Dimethoxyphenyl)(pyridin-2-ylamino)methyl)quinolin-8-ol chemical structure, C23H21N3O3, CAS 352706-12-8

7-((3,4-Dimethoxyphenyl)(pyridin-2-ylamino)methyl)quinolin-8-ol

CAS 352706-12-8C₂₃H₂₁N₃O₃

2-Methyl-7-[[(6-methylpyridin-2-yl)amino]-(2-nitrophenyl)methyl]quinolin-8-ol chemical structure, C23H20N4O3, CAS 354782-29-9

2-Methyl-7-[[(6-methylpyridin-2-yl)amino]-(2-nitrophenyl)methyl]quinolin-8-ol

CAS 354782-29-9C₂₃H₂₀N₄O₃

7-[(4-Fluorophenyl)-[(6-methylpyridin-2-yl)amino]methyl]-2-methylquinolin-8-ol chemical structure, C23H20FN3O, CAS 354783-84-9

7-[(4-Fluorophenyl)-[(6-methylpyridin-2-yl)amino]methyl]-2-methylquinolin-8-ol

CAS 354783-84-9C₂₃H₂₀FN₃O

7-((3-Hydroxyphenyl)(pyridin-2-ylamino)methyl)-2-methylquinolin-8-ol chemical structure, C22H19N3O2, CAS 353519-17-2

7-((3-Hydroxyphenyl)(pyridin-2-ylamino)methyl)-2-methylquinolin-8-ol

CAS 353519-17-2C₂₂H₁₉N₃O₂

7-[(4-Fluorophenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol chemical structure, C22H18FN3O, CAS 353517-00-7

7-[(4-Fluorophenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol

CAS 353517-00-7C₂₂H₁₈FN₃O

BoNT-IN-2 chemical structure, C25H26N4O, CAS 354784-03-5

CAS 354784-03-5C₂₅H₂₆N₄O

7-((2,4-Dichlorophenyl)(pyridin-2-ylamino)methyl)quinolin-8-ol chemical structure, C21H15Cl2N3O, CAS 315698-29-4

7-((2,4-Dichlorophenyl)(pyridin-2-ylamino)methyl)quinolin-8-ol

CAS 315698-29-4C₂₁H₁₅Cl₂N₃O

7-[(4-Fluorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol chemical structure, C21H16FN3O, CAS 308298-20-6

7-[(4-Fluorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol

CAS 308298-20-6C₂₁H₁₆FN₃O

2-Methyl-7-{[(6-methylpyridin-2-yl)amino](3,4,5-trimethoxyphenyl)methyl}quinolin-8-ol chemical structure, C26H27N3O4, CAS 354785-70-9

2-Methyl-7-{[(6-methylpyridin-2-yl)amino](3,4,5-trimethoxyphenyl)methyl}quinolin-8-ol

CAS 354785-70-9C₂₆H₂₇N₃O₄

2-Methyl-7-[[(6-methylpyridin-2-yl)amino]-(4-nitrophenyl)methyl]quinolin-8-ol chemical structure, C23H20N4O3, CAS 354778-95-3

2-Methyl-7-[[(6-methylpyridin-2-yl)amino]-(4-nitrophenyl)methyl]quinolin-8-ol

CAS 354778-95-3C₂₃H₂₀N₄O₃

7-((2-Fluorophenyl)(pyridin-2-ylamino)methyl)quinolin-8-ol chemical structure, C21H16FN3O, CAS 442642-02-6

7-((2-Fluorophenyl)(pyridin-2-ylamino)methyl)quinolin-8-ol

CAS 442642-02-6C₂₁H₁₆FN₃O