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Murcko scaffold

Ring system with 2 rings and 17 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
22
With full pages
15
Scaffold SMILES

O=C(C=Cc1ccccc1)Nc1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)Nc1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

(E)-3-(2-Chlorophenyl)-N-pyridin-3-ylprop-2-enamide chemical structure, C14H11ClN2O, CAS 349433-39-2
(E)-3-(2-Chlorophenyl)-N-pyridin-3-ylprop-2-enamide
CAS 349433-39-2C14H11ClN2O
(2E)-3-(3-Nitrophenyl)-N-(pyridin-3-yl)prop-2-enamide chemical structure, C14H11N3O3, CAS 25844-43-3
(2E)-3-(3-Nitrophenyl)-N-(pyridin-3-yl)prop-2-enamide
CAS 25844-43-3C14H11N3O3
(E)-N-Pyridin-3-yl-3-(3,4,5-trimethoxyphenyl)prop-2-enamide chemical structure, C17H18N2O4, CAS 69708-46-9
(E)-N-Pyridin-3-yl-3-(3,4,5-trimethoxyphenyl)prop-2-enamide
CAS 69708-46-9C17H18N2O4
(E)-3-(4-Chloro-3-nitrophenyl)-N-pyridin-3-ylprop-2-enamide chemical structure, C14H10ClN3O3, CAS 1164547-07-2
(E)-3-(4-Chloro-3-nitrophenyl)-N-pyridin-3-ylprop-2-enamide
CAS 1164547-07-2C14H10ClN3O3
(2E)-3-Phenyl-N-(pyridin-3-yl)prop-2-enamide chemical structure, C14H12N2O, CAS 340258-16-4
(2E)-3-Phenyl-N-(pyridin-3-yl)prop-2-enamide
CAS 340258-16-4C14H12N2O
3-(3,4-Dichlorophenyl)-N-(3-pyridinyl)acrylamide chemical structure, C14H10Cl2N2O, CAS 540793-12-2
3-(3,4-Dichlorophenyl)-N-(3-pyridinyl)acrylamide
CAS 540793-12-2C14H10Cl2N2O
(E)-N-(2-Chloropyridin-3-yl)-3-phenylprop-2-enamide chemical structure, C14H11ClN2O, CAS 488096-14-6
(E)-N-(2-Chloropyridin-3-yl)-3-phenylprop-2-enamide
CAS 488096-14-6C14H11ClN2O
(E)-N-(2-Chloropyridin-3-yl)-3-(4-methoxyphenyl)prop-2-enamide chemical structure, C15H13ClN2O2, CAS 487037-57-0
(E)-N-(2-Chloropyridin-3-yl)-3-(4-methoxyphenyl)prop-2-enamide
CAS 487037-57-0C15H13ClN2O2
(E)-N-(2-Chloropyridin-3-yl)-3-(2-methoxyphenyl)prop-2-enamide chemical structure, C15H13ClN2O2, CAS 489443-43-8
(E)-N-(2-Chloropyridin-3-yl)-3-(2-methoxyphenyl)prop-2-enamide
CAS 489443-43-8C15H13ClN2O2
(E)-2-Cyano-3-phenyl-N-pyridin-3-ylprop-2-enamide chemical structure, C15H11N3O, CAS 497245-08-6
(E)-2-Cyano-3-phenyl-N-pyridin-3-ylprop-2-enamide
CAS 497245-08-6C15H11N3O
(E)-3-(4-Butoxy-3-methoxyphenyl)-2-cyano-N-(pyridin-3-yl)acrylamide chemical structure, C20H21N3O3, CAS 496021-40-0
(E)-3-(4-Butoxy-3-methoxyphenyl)-2-cyano-N-(pyridin-3-yl)acrylamide
CAS 496021-40-0C20H21N3O3
(E)-2-Cyano-3-(2-hydroxyphenyl)-N-pyridin-3-ylprop-2-enamide chemical structure, C15H11N3O2, CAS 496021-36-4
(E)-2-Cyano-3-(2-hydroxyphenyl)-N-pyridin-3-ylprop-2-enamide
CAS 496021-36-4C15H11N3O2
(E)-2-Cyano-3-(2-propoxyphenyl)-N-pyridin-3-ylprop-2-enamide chemical structure, C18H17N3O2, CAS 500103-76-4
(E)-2-Cyano-3-(2-propoxyphenyl)-N-pyridin-3-ylprop-2-enamide
CAS 500103-76-4C18H17N3O2
2-Cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide chemical structure, C16H11F2N3O2, CAS 328036-06-2
2-Cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide
CAS 328036-06-2C16H11F2N3O2
2-Cyano-3-(3,4-dimethoxyphenyl)-N-(pyridin-3-yl)prop-2-enamide chemical structure, C17H15N3O3, CAS 380426-82-4
2-Cyano-3-(3,4-dimethoxyphenyl)-N-(pyridin-3-yl)prop-2-enamide
CAS 380426-82-4C17H15N3O3
N-Pyridin-3-yl-3-(2,3,4-trimethoxyphenyl)prop-2-enamide chemical structure, C17H18N2O4, CAS 5868-69-9
N-Pyridin-3-yl-3-(2,3,4-trimethoxyphenyl)prop-2-enamide
CAS 5868-69-9C17H18N2O4
(2E)-3-(4-Chlorophenyl)-2-cyano-N-(pyridin-3-yl)prop-2-enamide chemical structure, C15H10ClN3O, CAS 496021-34-2
(2E)-3-(4-Chlorophenyl)-2-cyano-N-(pyridin-3-yl)prop-2-enamide
CAS 496021-34-2C15H10ClN3O
3-(2,4-Dichlorophenyl)-N-(2,6-dimethoxypyridin-3-yl)prop-2-enamide chemical structure, C16H14Cl2N2O3, CAS 821005-50-9
3-(2,4-Dichlorophenyl)-N-(2,6-dimethoxypyridin-3-yl)prop-2-enamide
CAS 821005-50-9C16H14Cl2N2O3
3-(2-Chlorophenyl)-N-(2,6-dimethoxypyridin-3-yl)prop-2-enamide chemical structure, C16H15ClN2O3, CAS 821005-48-5
3-(2-Chlorophenyl)-N-(2,6-dimethoxypyridin-3-yl)prop-2-enamide
CAS 821005-48-5C16H15ClN2O3
2-(N-Hydroxyimino)-3-oxo-3-phenyl-N-(pyridin-3-yl)propanamide chemical structure, C14H11N3O3, CAS 565179-67-1
2-(N-Hydroxyimino)-3-oxo-3-phenyl-N-(pyridin-3-yl)propanamide
CAS 565179-67-1C14H11N3O3
(E)-3-Hydroxy-2-nitroso-3-phenyl-N-pyridin-3-ylprop-2-enamide chemical structure, C14H11N3O3
(E)-3-Hydroxy-2-nitroso-3-phenyl-N-pyridin-3-ylprop-2-enamide
C14H11N3O3
(Z)-3-Hydroxy-2-nitroso-3-phenyl-N-pyridin-3-ylprop-2-enamide chemical structure, C14H11N3O3
(Z)-3-Hydroxy-2-nitroso-3-phenyl-N-pyridin-3-ylprop-2-enamide
C14H11N3O3