CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(C=Cc1ccc2c(c1)OCO2)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc2c(c1)OCO2)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

(E)-3-(1,3-Benzodioxol-5-yl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide chemical structure, C12H9N3O3S, CAS 349541-49-7
(E)-3-(1,3-Benzodioxol-5-yl)-N-(1,3,4-thiadiazol-2-yl)prop-2-enamide
CAS 349541-49-7C12H9N3O3S
(E)-3-(1,3-Benzodioxol-5-yl)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)prop-2-enamide chemical structure, C15H15N3O3S, CAS 476462-97-2
(E)-3-(1,3-Benzodioxol-5-yl)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)prop-2-enamide
CAS 476462-97-2C15H15N3O3S
(E)-3-(1,3-Benzodioxol-5-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)prop-2-enamide chemical structure, C13H11N3O3S, CAS 346726-06-5
(E)-3-(1,3-Benzodioxol-5-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)prop-2-enamide
CAS 346726-06-5C13H11N3O3S
(E)-3-(1,3-Benzodioxol-5-yl)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide chemical structure, C14H13N3O4S, CAS 690966-42-8
(E)-3-(1,3-Benzodioxol-5-yl)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide
CAS 690966-42-8C14H13N3O4S
(E)-3-(1,3-Benzodioxol-5-yl)-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)prop-2-enamide chemical structure, C14H13N3O3S2, CAS 1164498-87-6
(E)-3-(1,3-Benzodioxol-5-yl)-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)prop-2-enamide
CAS 1164498-87-6C14H13N3O3S2
3-(2H-1,3-Benzodioxol-5-yl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide chemical structure, C13H8F3N3O3S, CAS 4422-41-7
3-(2H-1,3-Benzodioxol-5-yl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide
CAS 4422-41-7C13H8F3N3O3S
(E)-3-(1,3-Benzodioxol-5-yl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide chemical structure, C13H8F3N3O3S, CAS 521294-99-5
(E)-3-(1,3-Benzodioxol-5-yl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide
CAS 521294-99-5C13H8F3N3O3S
(Z)-3-(Benzo[d][1,3]dioxol-5-yl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acrylamide chemical structure, C14H13N3O3S, CAS 424806-60-0
(Z)-3-(Benzo[d][1,3]dioxol-5-yl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acrylamide
CAS 424806-60-0C14H13N3O3S
(Z)-Methyl 2-((5-(3-(benzo[d][1,3]dioxol-5-yl)acrylamido)-1,3,4-thiadiazol-2-yl)thio)acetate chemical structure, C15H13N3O5S2, CAS 1164487-34-6
(Z)-Methyl 2-((5-(3-(benzo[d][1,3]dioxol-5-yl)acrylamido)-1,3,4-thiadiazol-2-yl)thio)acetate
CAS 1164487-34-6C15H13N3O5S2
(Z)-3-(Benzo[d][1,3]dioxol-5-yl)-N-(5-(methylthio)-1,3,4-thiadiazol-2-yl)acrylamide chemical structure, C13H11N3O3S2, CAS 476464-06-9
(Z)-3-(Benzo[d][1,3]dioxol-5-yl)-N-(5-(methylthio)-1,3,4-thiadiazol-2-yl)acrylamide
CAS 476464-06-9C13H11N3O3S2
(Z)-Ethyl 2-((5-(3-(benzo[d][1,3]dioxol-5-yl)acrylamido)-1,3,4-thiadiazol-2-yl)thio)acetate chemical structure, C16H15N3O5S2, CAS 476465-11-9
(Z)-Ethyl 2-((5-(3-(benzo[d][1,3]dioxol-5-yl)acrylamido)-1,3,4-thiadiazol-2-yl)thio)acetate
CAS 476465-11-9C16H15N3O5S2
(E)-Ethyl 2-(2-((5-(3-(benzo[d][1,3]dioxol-5-yl)acrylamido)-1,3,4-thiadiazol-2-yl)thio)acetamido)acetate chemical structure, C18H18N4O6S2, CAS 1321914-49-1
(E)-Ethyl 2-(2-((5-(3-(benzo[d][1,3]dioxol-5-yl)acrylamido)-1,3,4-thiadiazol-2-yl)thio)acetamido)acetate
CAS 1321914-49-1C18H18N4O6S2