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Murcko scaffold

2-Phenoxypyrazine scaffold

203 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
203
With full pages
29
Scaffold SMILES

c1ccc(Oc2cnccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenoxypyrazine page
Murcko scaffold c1ccc(Oc2cnccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 203 chemicals

2-(Nonan-5-yl)-3-phenoxypyrazine chemical structure, C19H26N2O, CAS 5008-87-7
2-(Nonan-5-yl)-3-phenoxypyrazine
CAS 5008-87-7C19H26N2O
2-Phenoxypyrazine chemical structure, C10H8N2O, CAS 107697-82-5
2-Phenoxypyrazine
CAS 107697-82-5C10H8N2O
2-Methyl-3-phenoxypyrazine chemical structure, C11H10N2O, CAS 91137-78-9
2-Methyl-3-phenoxypyrazine
CAS 91137-78-9C11H10N2O
3-Methyl-5-(2-methylbutyl)-2-phenoxypyrazine chemical structure, C16H20N2O, CAS 99784-20-0
3-Methyl-5-(2-methylbutyl)-2-phenoxypyrazine
CAS 99784-20-0C16H20N2O
5-Isobutyl-3-methyl-2-phenoxypyrazine chemical structure, C15H18N2O, CAS 78246-16-9
5-Isobutyl-3-methyl-2-phenoxypyrazine
CAS 78246-16-9C15H18N2O
5-Isopropyl-3-methyl-2-phenoxypyrazine chemical structure, C14H16N2O, CAS 99784-18-6
5-Isopropyl-3-methyl-2-phenoxypyrazine
CAS 99784-18-6C14H16N2O
5-sec-Butyl-3-methyl-2-phenoxypyrazine chemical structure, C15H18N2O, CAS 99784-19-7
5-sec-Butyl-3-methyl-2-phenoxypyrazine
CAS 99784-19-7C15H18N2O
Pyrazine, 2-pentyl-3-phenoxy chemical structure, C15H18N2O, CAS 113685-85-1
Pyrazine, 2-pentyl-3-phenoxy
CAS 113685-85-1C15H18N2O
3-[3-(Trifluoromethyl)phenoxy]pyrazine-2-carboxamide chemical structure, C12H8F3N3O2, CAS 874832-16-3
3-[3-(Trifluoromethyl)phenoxy]pyrazine-2-carboxamide
CAS 874832-16-3C12H8F3N3O2
3-Phenoxypyrazine-2-carbonitrile chemical structure, C11H7N3O, CAS 87542-50-5
3-Phenoxypyrazine-2-carbonitrile
CAS 87542-50-5C11H7N3O
3-(2,4-Difluorophenoxy)pyrazine-2-carbonitrile chemical structure, C11H5F2N3O, CAS 303146-93-2
3-(2,4-Difluorophenoxy)pyrazine-2-carbonitrile
CAS 303146-93-2C11H5F2N3O
3-(2-Chlorophenoxy)pyrazine-2-carbonitrile chemical structure, C11H6ClN3O, CAS 303146-94-3
3-(2-Chlorophenoxy)pyrazine-2-carbonitrile
CAS 303146-94-3C11H6ClN3O
3-(2,4-Dichlorophenoxy)pyrazine-2-carbonitrile chemical structure, C11H5Cl2N3O, CAS 303146-95-4
3-(2,4-Dichlorophenoxy)pyrazine-2-carbonitrile
CAS 303146-95-4C11H5Cl2N3O
3-[3-(Trifluoromethyl)phenoxy]pyrazine-2-carboxylic acid chemical structure, C12H7F3N2O3, CAS 518057-62-0
3-[3-(Trifluoromethyl)phenoxy]pyrazine-2-carboxylic acid
CAS 518057-62-0C12H7F3N2O3
3-[3-(Trifluoromethyl)phenoxy]pyrazine-2-carbonitrile chemical structure, C12H6F3N3O, CAS 176162-29-1
3-[3-(Trifluoromethyl)phenoxy]pyrazine-2-carbonitrile
CAS 176162-29-1C12H6F3N3O
3-(4-Chlorophenoxy)pyrazine-2-carbonitrile chemical structure, C11H6ClN3O, CAS 303146-83-0
3-(4-Chlorophenoxy)pyrazine-2-carbonitrile
CAS 303146-83-0C11H6ClN3O
3-(4-Methoxyphenoxy)pyrazine-2-carbonitrile chemical structure, C12H9N3O2, CAS 303146-53-4
3-(4-Methoxyphenoxy)pyrazine-2-carbonitrile
CAS 303146-53-4C12H9N3O2
3-Methoxy-4-(2-pyrazinyloxy)benzenecarbaldehyde chemical structure, C12H10N2O3, CAS 866042-88-8
3-Methoxy-4-(2-pyrazinyloxy)benzenecarbaldehyde
CAS 866042-88-8C12H10N2O3
4-(Pyrazin-2-yloxy)benzaldehyde chemical structure, C11H8N2O2, CAS 866156-93-6
4-(Pyrazin-2-yloxy)benzaldehyde
CAS 866156-93-6C11H8N2O2
2-[5-Methyl-2-(1-methylethyl)phenoxy]pyrazine chemical structure, C14H16N2O, CAS 866043-36-9
2-[5-Methyl-2-(1-methylethyl)phenoxy]pyrazine
CAS 866043-36-9C14H16N2O
1-[4-(2-Pyrazinyloxy)phenyl]-1-propanone chemical structure, C13H12N2O2, CAS 866156-99-2
1-[4-(2-Pyrazinyloxy)phenyl]-1-propanone
CAS 866156-99-2C13H12N2O2
3-(Pyrazin-2-yloxy)aniline chemical structure, C10H9N3O, CAS 633300-16-0
3-(Pyrazin-2-yloxy)aniline
CAS 633300-16-0C10H9N3O
2-Chloro-N-[3-(2-pyrazinyloxy)phenyl]acetamide chemical structure, C12H10ClN3O2, CAS 866157-08-6
2-Chloro-N-[3-(2-pyrazinyloxy)phenyl]acetamide
CAS 866157-08-6C12H10ClN3O2
1-[4-(2-Pyrazinyloxy)phenyl]-1-ethanol chemical structure, C12H12N2O2, CAS 866157-14-4
1-[4-(2-Pyrazinyloxy)phenyl]-1-ethanol
CAS 866157-14-4C12H12N2O2