CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
11
With full pages
5
Scaffold SMILES

O=C(Cn1cnc2ccccc21)Oc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1cnc2ccccc21)Oc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

3-(Trifluoromethyl)phenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C17H10F6N2O2, CAS 478065-82-6
3-(Trifluoromethyl)phenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 478065-82-6C17H10F6N2O2
4-(Acetylamino)phenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C18H14F3N3O3, CAS 672950-99-1
4-(Acetylamino)phenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 672950-99-1C18H14F3N3O3
4-(tert-Butyl)phenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C20H19F3N2O2, CAS 672951-00-7
4-(tert-Butyl)phenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 672951-00-7C20H19F3N2O2
3-Methylphenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C17H13F3N2O2, CAS 672950-91-3
3-Methylphenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 672950-91-3C17H13F3N2O2
2-Methylphenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C17H13F3N2O2, CAS 672950-92-4
2-Methylphenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 672950-92-4C17H13F3N2O2
4-Methylphenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C17H13F3N2O2, CAS 672950-93-5
4-Methylphenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 672950-93-5C17H13F3N2O2
Methyl 2-({2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetyl}oxy)benzenecarboxylate chemical structure, C18H13F3N2O4, CAS 672950-97-9
Methyl 2-({2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetyl}oxy)benzenecarboxylate
CAS 672950-97-9C18H13F3N2O4
4-Cyanophenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C17H10F3N3O2, CAS 672950-98-0
4-Cyanophenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 672950-98-0C17H10F3N3O2
2,4-Dichlorophenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C16H9Cl2F3N2O2, CAS 672951-05-2
2,4-Dichlorophenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 672951-05-2C16H9Cl2F3N2O2
2,5-Dichlorophenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C16H9Cl2F3N2O2, CAS 672951-06-3
2,5-Dichlorophenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 672951-06-3C16H9Cl2F3N2O2
2-Isopropyl-5-methylphenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate chemical structure, C20H19F3N2O2, CAS 551921-10-9
2-Isopropyl-5-methylphenyl 2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]acetate
CAS 551921-10-9C20H19F3N2O2