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Murcko scaffold

Ring system with 3 rings and 19 atoms

116 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
116
With full pages
8
Scaffold SMILES

O=C(Cc1coc2ccccc12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1coc2ccccc12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 116 chemicals

N-(4-Methoxyphenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide chemical structure, C18H17NO3, CAS 831186-83-5
N-(4-Methoxyphenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
CAS 831186-83-5C18H17NO3
N-(2-Bromophenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide chemical structure, C17H14BrNO2, CAS 831209-48-4
N-(2-Bromophenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
CAS 831209-48-4C17H14BrNO2
N-(2,4-Dimethylphenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide chemical structure, C19H19NO2, CAS 831230-55-8
N-(2,4-Dimethylphenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
CAS 831230-55-8C19H19NO2
Methyl 2-{[(6,7-dimethyl-1-benzofuran-3-yl)acetyl]amino}benzoate chemical structure, C20H19NO4, CAS 714206-26-5
Methyl 2-{[(6,7-dimethyl-1-benzofuran-3-yl)acetyl]amino}benzoate
CAS 714206-26-5C20H19NO4
N-(2,4-Dimethoxyphenyl)-2-(6,7-dimethyl-1-benzofuran-3-yl)acetamide chemical structure, C20H21NO4, CAS 713504-40-6
N-(2,4-Dimethoxyphenyl)-2-(6,7-dimethyl-1-benzofuran-3-yl)acetamide
CAS 713504-40-6C20H21NO4
N-(2,4-Dimethoxyphenyl)-2-(4,6-dimethyl-1-benzofuran-3-yl)acetamide chemical structure, C20H21NO4, CAS 713506-26-4
N-(2,4-Dimethoxyphenyl)-2-(4,6-dimethyl-1-benzofuran-3-yl)acetamide
CAS 713506-26-4C20H21NO4
N-(2,5-Dimethoxyphenyl)-2-(4,6-dimethyl-1-benzofuran-3-yl)acetamide chemical structure, C20H21NO4, CAS 714206-27-6
N-(2,5-Dimethoxyphenyl)-2-(4,6-dimethyl-1-benzofuran-3-yl)acetamide
CAS 714206-27-6C20H21NO4
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-(2,3-dimethylphenyl)acetamide chemical structure, C20H21NO2, CAS 780774-60-9
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-(2,3-dimethylphenyl)acetamide
CAS 780774-60-9C20H21NO2
Methyl 2-{[(4,6-dimethyl-1-benzofuran-3-yl)acetyl]amino}benzoate chemical structure, C20H19NO4, CAS 714204-75-8
Methyl 2-{[(4,6-dimethyl-1-benzofuran-3-yl)acetyl]amino}benzoate
CAS 714204-75-8C20H19NO4
N-(2,5-Dichlorophenyl)-2-(6,7-dimethyl-1-benzofuran-3-yl)acetamide chemical structure, C18H15Cl2NO2, CAS 780774-64-3
N-(2,5-Dichlorophenyl)-2-(6,7-dimethyl-1-benzofuran-3-yl)acetamide
CAS 780774-64-3C18H15Cl2NO2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(3-methylphenyl)acetamide chemical structure, C19H19NO2, CAS 618859-44-2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(3-methylphenyl)acetamide
CAS 618859-44-2C19H19NO2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(4-methylphenyl)acetamide chemical structure, C19H19NO2, CAS 618859-45-3
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(4-methylphenyl)acetamide
CAS 618859-45-3C19H19NO2
N-(4-Acetamidophenyl)-2-(6-methyl-1-benzofuran-3-yl)acetamide chemical structure, C19H18N2O3, CAS 757197-54-9
N-(4-Acetamidophenyl)-2-(6-methyl-1-benzofuran-3-yl)acetamide
CAS 757197-54-9C19H18N2O3
2-(6-Methyl-1-benzofuran-3-yl)-N-(4-sulfamoylphenyl)acetamide chemical structure, C17H16N2O4S, CAS 782453-82-1
2-(6-Methyl-1-benzofuran-3-yl)-N-(4-sulfamoylphenyl)acetamide
CAS 782453-82-1C17H16N2O4S
2-(5-Methyl-1-benzofuran-3-yl)-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C18H14F3NO2, CAS 830344-76-8
2-(5-Methyl-1-benzofuran-3-yl)-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 830344-76-8C18H14F3NO2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(4-ethylphenyl)acetamide chemical structure, C20H21NO2, CAS 830345-23-8
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(4-ethylphenyl)acetamide
CAS 830345-23-8C20H21NO2
N-(2-Ethoxyphenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide chemical structure, C19H19NO3, CAS 830350-36-2
N-(2-Ethoxyphenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
CAS 830350-36-2C19H19NO3
N-(4-Chlorophenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide chemical structure, C17H14ClNO2, CAS 830351-19-4
N-(4-Chlorophenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
CAS 830351-19-4C17H14ClNO2
2-(5-Ethyl-1-benzofuran-3-yl)-N-(3-methylphenyl)acetamide chemical structure, C19H19NO2, CAS 831184-44-2
2-(5-Ethyl-1-benzofuran-3-yl)-N-(3-methylphenyl)acetamide
CAS 831184-44-2C19H19NO2
N-(2-Chlorophenyl)-2-(4,6-dimethyl-1-benzofuran-3-yl)acetamide chemical structure, C18H16ClNO2, CAS 831214-59-6
N-(2-Chlorophenyl)-2-(4,6-dimethyl-1-benzofuran-3-yl)acetamide
CAS 831214-59-6C18H16ClNO2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(4-fluorophenyl)acetamide chemical structure, C18H16FNO2, CAS 831229-81-3
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(4-fluorophenyl)acetamide
CAS 831229-81-3C18H16FNO2
N-(5-Chloro-2-methoxyphenyl)-2-(5,6-dimethyl-1-benzofuran-3-yl)acetamide chemical structure, C19H18ClNO3, CAS 794575-27-2
N-(5-Chloro-2-methoxyphenyl)-2-(5,6-dimethyl-1-benzofuran-3-yl)acetamide
CAS 794575-27-2C19H18ClNO3
N-(2-Ethoxyphenyl)-2-(6-methyl-1-benzofuran-3-yl)acetamide chemical structure, C19H19NO3, CAS 848050-78-2
N-(2-Ethoxyphenyl)-2-(6-methyl-1-benzofuran-3-yl)acetamide
CAS 848050-78-2C19H19NO3
N-(2,5-Dimethylphenyl)-2-(6-methyl-1-benzofuran-3-yl)acetamide chemical structure, C19H19NO2, CAS 801271-74-9
N-(2,5-Dimethylphenyl)-2-(6-methyl-1-benzofuran-3-yl)acetamide
CAS 801271-74-9C19H19NO2