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Murcko scaffold

Ring system with 3 rings and 19 atoms

277 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
277
With full pages
16
Scaffold SMILES

O=C(Cn1ccc2ccccc21)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1ccc2ccccc21)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 277 chemicals

N-(3,5-Dimethylphenyl)-3-formyl-1H-indole-1-acetamide chemical structure, C19H18N2O2, CAS 329061-81-6
N-(3,5-Dimethylphenyl)-3-formyl-1H-indole-1-acetamide
CAS 329061-81-6C19H18N2O2
2-(3-Cyano-2-methylindol-1-yl)-N-(4-ethoxyphenyl)acetamide chemical structure, C20H19N3O2, CAS 640257-26-7
2-(3-Cyano-2-methylindol-1-yl)-N-(4-ethoxyphenyl)acetamide
CAS 640257-26-7C20H19N3O2
N-(3,5-Dimethylphenyl)-3-formyl-2-methyl-1H-indole-1-acetamide chemical structure, C20H20N2O2, CAS 309732-87-4
N-(3,5-Dimethylphenyl)-3-formyl-2-methyl-1H-indole-1-acetamide
CAS 309732-87-4C20H20N2O2
2-(1H-Indol-1-yl)-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C17H13F3N2O, CAS 329777-45-9
2-(1H-Indol-1-yl)-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 329777-45-9C17H13F3N2O
2-[(3E)-3-(Hydroxyimino)-2-oxo-2,3-dihydro-1H-indol-1-yl]-N-phenylacetamide chemical structure, C16H13N3O3, CAS 302968-25-8
2-[(3E)-3-(Hydroxyimino)-2-oxo-2,3-dihydro-1H-indol-1-yl]-N-phenylacetamide
CAS 302968-25-8C16H13N3O3
N-(3,4-Dimethylphenyl)-2-(3-formyl-1H-indol-1-yl)acetamide chemical structure, C19H18N2O2, CAS 328974-17-0
N-(3,4-Dimethylphenyl)-2-(3-formyl-1H-indol-1-yl)acetamide
CAS 328974-17-0C19H18N2O2
N-(2,3-Dimethylphenyl)-2-(3-formyl-1H-indol-1-yl)acetamide chemical structure, C19H18N2O2, CAS 496960-29-3
N-(2,3-Dimethylphenyl)-2-(3-formyl-1H-indol-1-yl)acetamide
CAS 496960-29-3C19H18N2O2
2-(3-Formyl-1H-indol-1-yl)-N-(p-tolyl)acetamide chemical structure, C18H16N2O2, CAS 333745-03-2
2-(3-Formyl-1H-indol-1-yl)-N-(p-tolyl)acetamide
CAS 333745-03-2C18H16N2O2
N-(2,4-Dimethylphenyl)-2-(3-formyl-1H-indol-1-yl)acetamide chemical structure, C19H18N2O2, CAS 385420-16-6
N-(2,4-Dimethylphenyl)-2-(3-formyl-1H-indol-1-yl)acetamide
CAS 385420-16-6C19H18N2O2
Methyl 2-(2-(3-formyl-1H-indol-1-yl)acetamido)benzoate chemical structure, C19H16N2O4, CAS 592546-80-0
Methyl 2-(2-(3-formyl-1H-indol-1-yl)acetamido)benzoate
CAS 592546-80-0C19H16N2O4
N-(4-Fluorophenyl)-2-(3-formyl-2-methyl-1H-indol-1-yl)acetamide chemical structure, C18H15FN2O2, CAS 433248-81-8
N-(4-Fluorophenyl)-2-(3-formyl-2-methyl-1H-indol-1-yl)acetamide
CAS 433248-81-8C18H15FN2O2
2-(3-Formyl-1H-indol-1-yl)-N-phenylacetamide chemical structure, C17H14N2O2, CAS 333745-18-9
2-(3-Formyl-1H-indol-1-yl)-N-phenylacetamide
CAS 333745-18-9C17H14N2O2
2-(3-Formyl-indol-1-yl)-N-m-tolyl-acetamide chemical structure, C18H16N2O2, CAS 333745-01-0
2-(3-Formyl-indol-1-yl)-N-m-tolyl-acetamide
CAS 333745-01-0C18H16N2O2
N-(3,4-Dichlorophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide chemical structure, C17H12Cl2N2O2, CAS 500268-18-8
N-(3,4-Dichlorophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide
CAS 500268-18-8C17H12Cl2N2O2
N-(3,4-Dimethylphenyl)-2-(3-formyl-2-methyl-1H-indol-1-yl)acetamide chemical structure, C20H20N2O2, CAS 347320-01-8
N-(3,4-Dimethylphenyl)-2-(3-formyl-2-methyl-1H-indol-1-yl)acetamide
CAS 347320-01-8C20H20N2O2
2-(3-Formyl-1H-indol-1-yl)-N-(3-methoxyphenyl)acetamide chemical structure, C18H16N2O3, CAS 496959-22-9
2-(3-Formyl-1H-indol-1-yl)-N-(3-methoxyphenyl)acetamide
CAS 496959-22-9C18H16N2O3
N-(3,5-Dichlorophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide chemical structure, C17H12Cl2N2O2, CAS 496959-26-3
N-(3,5-Dichlorophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide
CAS 496959-26-3C17H12Cl2N2O2
2-(3-Formyl-1H-indol-1-yl)-N-(4-methoxyphenyl)acetamide chemical structure, C18H16N2O3, CAS 496960-30-6
2-(3-Formyl-1H-indol-1-yl)-N-(4-methoxyphenyl)acetamide
CAS 496960-30-6C18H16N2O3
N-(2,3-Dichlorophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide chemical structure, C17H12Cl2N2O2, CAS 496960-31-7
N-(2,3-Dichlorophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide
CAS 496960-31-7C17H12Cl2N2O2
Methyl 1-[2-(4-methylanilino)-2-oxoethyl]indole-3-carboxylate chemical structure, C19H18N2O3, CAS 723750-70-7
Methyl 1-[2-(4-methylanilino)-2-oxoethyl]indole-3-carboxylate
CAS 723750-70-7C19H18N2O3
N-(4-Fluorophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide chemical structure, C17H13FN2O2, CAS 428487-58-5
N-(4-Fluorophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide
CAS 428487-58-5C17H13FN2O2
2-(3-Formyl-1H-indol-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide chemical structure, C18H13F3N2O2, CAS 692280-64-1
2-(3-Formyl-1H-indol-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide
CAS 692280-64-1C18H13F3N2O2
2-(3-Hydroxymethyl-indol-1-yl)-N-m-tolyl-acetamide chemical structure, C18H18N2O2, CAS 693808-56-9
2-(3-Hydroxymethyl-indol-1-yl)-N-m-tolyl-acetamide
CAS 693808-56-9C18H18N2O2
2-(3-Cyanoindol-1-yl)-N-methyl-N-phenylacetamide chemical structure, C18H15N3O, CAS 678147-08-5
2-(3-Cyanoindol-1-yl)-N-methyl-N-phenylacetamide
CAS 678147-08-5C18H15N3O