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Murcko scaffold

5,6-Diphenylmorpholin-2-one scaffold

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
15
With full pages
4
Scaffold SMILES

O=C1CNC(c2ccccc2)C(c2ccccc2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6-Diphenylmorpholin-2-one page
Murcko scaffold O=C1CNC(c2ccccc2)C(c2ccccc2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1,1-Dimethylethyl (2S,3R)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate chemical structure, C21H23NO4, CAS 112741-50-1
1,1-Dimethylethyl (2S,3R)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
CAS 112741-50-1C21H23NO4
tert-Butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate chemical structure, C21H23NO4, CAS 112741-49-8
tert-Butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate
CAS 112741-49-8C21H23NO4
tert-Butyl 6-oxo-2,3-diphenyl-4-morpholinecarboxylate chemical structure, C21H23NO4, CAS 302911-78-0
tert-Butyl 6-oxo-2,3-diphenyl-4-morpholinecarboxylate
CAS 302911-78-0C21H23NO4
(5S,6R)-5,6-Diphenyl-2-morpholinone chemical structure, C16H15NO2, CAS 144538-22-7
(5S,6R)-5,6-Diphenyl-2-morpholinone
CAS 144538-22-7C16H15NO2
(3S,5S,6R)-3-(3-Butenyl)-2-oxo-5,6-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester chemical structure, C25H29NO4, CAS 144542-72-3
(3S,5S,6R)-3-(3-Butenyl)-2-oxo-5,6-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester
CAS 144542-72-3C25H29NO4
(5R,6S)-5.6-Diphenyl-2-morpholinone chemical structure, C16H15NO2, CAS 282735-66-4
(5R,6S)-5.6-Diphenyl-2-morpholinone
CAS 282735-66-4C16H15NO2
L-N-Boc-3-methylmorpholine chemical structure, C21H22BrNO4, CAS 127420-01-3
L-N-Boc-3-methylmorpholine
CAS 127420-01-3C21H22BrNO4
(3S,5S,6R)-tert-Butyl 3-bromo-2-oxo-5,6-diphenylmorpholine-4-carboxylate chemical structure, C21H22BrNO4, CAS 112741-51-2
(3S,5S,6R)-tert-Butyl 3-bromo-2-oxo-5,6-diphenylmorpholine-4-carboxylate
CAS 112741-51-2C21H22BrNO4
tert-Butyl (3R,5R,6S)-3-bromo-2-oxo-5,6-diphenylmorpholine-4-carboxylate chemical structure, C21H22BrNO4
tert-Butyl (3R,5R,6S)-3-bromo-2-oxo-5,6-diphenylmorpholine-4-carboxylate
C21H22BrNO4
5,6-Diphenylmorpholin-2-one chemical structure, C16H15NO2, CAS 19180-79-1
5,6-Diphenylmorpholin-2-one
CAS 19180-79-1C16H15NO2
(5S,6S)-5,6-Diphenylmorpholin-2-one chemical structure, C16H15NO2, CAS 1391544-79-8
(5S,6S)-5,6-Diphenylmorpholin-2-one
CAS 1391544-79-8C16H15NO2
(5R,6R)-5,6-Diphenylmorpholin-2-one chemical structure, C16H15NO2, CAS 2227197-35-3
(5R,6R)-5,6-Diphenylmorpholin-2-one
CAS 2227197-35-3C16H15NO2
(3R,5R,6S)-tert-Butyl 3-methyl-3-(oct-7-en-1-yl)-2-oxo-5,6-diphenylmorpholine-4-carboxylate chemical structure, C30H39NO4, CAS 1809308-80-2
(3R,5R,6S)-tert-Butyl 3-methyl-3-(oct-7-en-1-yl)-2-oxo-5,6-diphenylmorpholine-4-carboxylate
CAS 1809308-80-2C30H39NO4
tert-Butyl (3S,5S,6R)-3-[(3S)-4-bromo-3-hydroxybutyl]-2-oxo-5,6-diphenylmorpholine-4-carboxylate chemical structure, C25H30BrNO5, CAS 869111-54-6
tert-Butyl (3S,5S,6R)-3-[(3S)-4-bromo-3-hydroxybutyl]-2-oxo-5,6-diphenylmorpholine-4-carboxylate
CAS 869111-54-6C25H30BrNO5
(3S,5S,6R)-3-[(3R)-4-Bromo-3-hydroxybutyl]-2-oxo-5,6-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester chemical structure, C25H30BrNO5, CAS 869111-53-5
(3S,5S,6R)-3-[(3R)-4-Bromo-3-hydroxybutyl]-2-oxo-5,6-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester
CAS 869111-53-5C25H30BrNO5