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Murcko scaffold

2,3-Diphenylpyrazine scaffold

89 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
89
With full pages
8
Scaffold SMILES

c1ccc(-c2nccnc2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Diphenylpyrazine page
Murcko scaffold c1ccc(-c2nccnc2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 89 chemicals

2,3-Diphenylpyrazine chemical structure, C16H12N2, CAS 1588-89-2
2,3-Diphenylpyrazine
CAS 1588-89-2C16H12N2
5-Hydrazinyl-2,3-diphenylpyrazine chemical structure, C16H14N4, CAS 6969-74-0
5-Hydrazinyl-2,3-diphenylpyrazine
CAS 6969-74-0C16H14N4
5,6-Diphenylpyrazine-2,3-diamine chemical structure, C16H14N4, CAS 64163-37-7
5,6-Diphenylpyrazine-2,3-diamine
CAS 64163-37-7C16H14N4
2,3-Dibromo-5,6-diphenylpyrazine chemical structure, C16H10Br2N2, CAS 75163-71-2
2,3-Dibromo-5,6-diphenylpyrazine
CAS 75163-71-2C16H10Br2N2
2,3-Dichloro-5,6-diphenylpyrazine chemical structure, C16H10Cl2N2, CAS 57038-62-7
2,3-Dichloro-5,6-diphenylpyrazine
CAS 57038-62-7C16H10Cl2N2
2,3-Dicyano-5,6-diphenylpyrazine chemical structure, C18H10N4, CAS 52197-23-6
2,3-Dicyano-5,6-diphenylpyrazine
CAS 52197-23-6C18H10N4
5,6-Bis(4-methylphenyl)pyrazine-2,3-dicarbonitrile chemical structure, C20H14N4, CAS 52197-13-4
5,6-Bis(4-methylphenyl)pyrazine-2,3-dicarbonitrile
CAS 52197-13-4C20H14N4
3-Amino-N-butyl-5,6-diphenylpyrazine-2-carboxamide chemical structure, C21H22N4O, CAS 7509-57-1
3-Amino-N-butyl-5,6-diphenylpyrazine-2-carboxamide
CAS 7509-57-1C21H22N4O
5-Chloro-2,3-diphenylpyrazine 1-oxide chemical structure, C16H11ClN2O, CAS 83520-54-1
5-Chloro-2,3-diphenylpyrazine 1-oxide
CAS 83520-54-1C16H11ClN2O
5-Methoxy-2,3-diphenylpyrazine chemical structure, C17H14N2O, CAS 34121-90-9
5-Methoxy-2,3-diphenylpyrazine
CAS 34121-90-9C17H14N2O
3-Chloro-5,6-diphenylpyrazine-2-carbonitrile chemical structure, C17H10ClN3, CAS 34122-24-2
3-Chloro-5,6-diphenylpyrazine-2-carbonitrile
CAS 34122-24-2C17H10ClN3
5,6-Bis(4-bromophenyl)pyrazine-2,3-dicarbonitrile chemical structure, C18H8Br2N4, CAS 5015-35-0
5,6-Bis(4-bromophenyl)pyrazine-2,3-dicarbonitrile
CAS 5015-35-0C18H8Br2N4
5-Chloro-2,3-diphenylpyrazine chemical structure, C16H11ClN2, CAS 41270-66-0
5-Chloro-2,3-diphenylpyrazine
CAS 41270-66-0C16H11ClN2
Selexipag chemical structure, C26H32N4O4S, CAS 475086-01-2
Selexipag
CAS 475086-01-2C26H32N4O4S
2-(4-((5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino)butoxy)acetic acid chemical structure, C25H29N3O3, CAS 475085-57-5
2-(4-((5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino)butoxy)acetic acid
CAS 475085-57-5C25H29N3O3
5,6-Diphenyl-2-pyrazinecarboxylic acid chemical structure, C17H12N2O2, CAS 13515-07-6
5,6-Diphenyl-2-pyrazinecarboxylic acid
CAS 13515-07-6C17H12N2O2
5,6-Diphenylpyrazin-2-amine chemical structure, C16H13N3, CAS 41270-71-7
5,6-Diphenylpyrazin-2-amine
CAS 41270-71-7C16H13N3
5-Bromo-2,3-diphenylpyrazine chemical structure, C16H11BrN2, CAS 243472-70-0
5-Bromo-2,3-diphenylpyrazine
CAS 243472-70-0C16H11BrN2
5,6-Bis(4-chlorophenyl)-3-(N-(2-hydroxy-1-methylethyl)carbamoyl)pyrazine-2-carboxylic acid tert-butylester chemical structure, C25H25Cl2N3O4, CAS 811436-92-7
5,6-Bis(4-chlorophenyl)-3-(N-(2-hydroxy-1-methylethyl)carbamoyl)pyrazine-2-carboxylic acid tert-butylester
CAS 811436-92-7C25H25Cl2N3O4
5,6-Bis(4-chlorophenyl)-3-(tert-butoxycarbonyl)-pyrazine-2-carboxylic acid chemical structure, C22H18Cl2N2O4, CAS 811436-88-1
5,6-Bis(4-chlorophenyl)-3-(tert-butoxycarbonyl)-pyrazine-2-carboxylic acid
CAS 811436-88-1C22H18Cl2N2O4
2-Azido-5,6-diphenylpyrazine chemical structure, C16H11N5, CAS 76849-26-8
2-Azido-5,6-diphenylpyrazine
CAS 76849-26-8C16H11N5
2,3-Bis(3,5-dimethylphenyl)pyrazine chemical structure, C20H20N2, CAS 623157-28-8
2,3-Bis(3,5-dimethylphenyl)pyrazine
CAS 623157-28-8C20H20N2
2,3-Pyrazinedicarbonitrile, 5,6-bis[4-(dimethylamino)phenyl]- chemical structure, C22H20N6, CAS 888947-50-0
2,3-Pyrazinedicarbonitrile, 5,6-bis[4-(dimethylamino)phenyl]-
CAS 888947-50-0C22H20N6
1-Oxo-2,3-diphenyl-1lambda~5~-pyrazine chemical structure, C16H12N2O, CAS 61578-13-0
1-Oxo-2,3-diphenyl-1lambda~5~-pyrazine
CAS 61578-13-0C16H12N2O