CompoundList
Sign in
Murcko scaffold

1-(2-Diphenyl)piperazine scaffold

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
28
With full pages
3
Scaffold SMILES

c1ccc(-c2ccccc2N2CCNCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Diphenyl)piperazine page
Murcko scaffold c1ccc(-c2ccccc2N2CCNCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

1-(Biphenyl-2-yl)piperazine dihydrochloride chemical structure, C16H20Cl2N2, CAS 769944-87-8
1-(Biphenyl-2-yl)piperazine dihydrochloride
CAS 769944-87-8C16H20Cl2N2
1-(2-Diphenyl)piperazine chemical structure, C16H18N2, CAS 180698-18-4
1-(2-Diphenyl)piperazine
CAS 180698-18-4C16H18N2
1-(2 inverted exclamation mark-Methoxy-[1,1 inverted exclamation mark-biphenyl]-2-yl)piperazine chemical structure, C17H20N2O, CAS 1386928-10-4
1-(2 inverted exclamation mark-Methoxy-[1,1 inverted exclamation mark-biphenyl]-2-yl)piperazine
CAS 1386928-10-4C17H20N2O
LP-20 hydrochloride chemical structure, C17H21ClN2O, CAS 1386928-34-2
LP-20 hydrochloride
CAS 1386928-34-2C17H21ClN2O
1-(2-(4-Methoxyphenyl)phenyl)piperazine chemical structure, C17H20N2O, CAS 1386927-90-7
1-(2-(4-Methoxyphenyl)phenyl)piperazine
CAS 1386927-90-7C17H20N2O
4-(4-Biphenyl-2-yl-piperazin-1-yl)-butylamine chemical structure, C20H27N3, CAS 227776-31-0
4-(4-Biphenyl-2-yl-piperazin-1-yl)-butylamine
CAS 227776-31-0C20H27N3
1-{4'-Fluoro-[1,1'-biphenyl]-2-yl}piperazine chemical structure, C16H17FN2, CAS 1386927-82-7
1-{4'-Fluoro-[1,1'-biphenyl]-2-yl}piperazine
CAS 1386927-82-7C16H17FN2
1-Methyl-4-(5-nitrobiphenyl-2-yl)piperazine chemical structure, C17H19N3O2, CAS 1254056-59-1
1-Methyl-4-(5-nitrobiphenyl-2-yl)piperazine
CAS 1254056-59-1C17H19N3O2
1-([1,1'-Biphenyl]-2-yl)piperazine hydrochloride chemical structure, C16H19ClN2, CAS 1386928-18-2
1-([1,1'-Biphenyl]-2-yl)piperazine hydrochloride
CAS 1386928-18-2C16H19ClN2
tert-Butyl 4-(5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C22H26N2O3, CAS 2126812-70-0
tert-Butyl 4-(5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2126812-70-0C22H26N2O3
tert-Butyl 4-(5-formyl-2'-methyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H28N2O3, CAS 2989213-52-5
tert-Butyl 4-(5-formyl-2'-methyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2989213-52-5C23H28N2O3
tert-Butyl 4-(2'-fluoro-5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C22H25FN2O3, CAS 2990517-99-0
tert-Butyl 4-(2'-fluoro-5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2990517-99-0C22H25FN2O3
tert-Butyl 4-(2'-chloro-5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C22H25ClN2O3, CAS 2990093-42-8
tert-Butyl 4-(2'-chloro-5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2990093-42-8C22H25ClN2O3
tert-Butyl 4-(5-formyl-2'-methoxy-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H28N2O4, CAS 2990113-05-6
tert-Butyl 4-(5-formyl-2'-methoxy-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2990113-05-6C23H28N2O4
tert-Butyl 4-(5-formyl-2'-(trifluoromethoxy)-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H25F3N2O4, CAS 2989900-52-7
tert-Butyl 4-(5-formyl-2'-(trifluoromethoxy)-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2989900-52-7C23H25F3N2O4
tert-Butyl 4-(5-formyl-3'-methyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H28N2O3, CAS 2990518-06-2
tert-Butyl 4-(5-formyl-3'-methyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2990518-06-2C23H28N2O3
tert-Butyl 4-(5-formyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H25F3N2O3, CAS 2988149-95-5
tert-Butyl 4-(5-formyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2988149-95-5C23H25F3N2O3
tert-Butyl 4-(3'-chloro-5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C22H25ClN2O3, CAS 2988310-00-3
tert-Butyl 4-(3'-chloro-5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2988310-00-3C22H25ClN2O3
tert-Butyl 4-(5-formyl-3'-methoxy-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H28N2O4, CAS 2989373-83-1
tert-Butyl 4-(5-formyl-3'-methoxy-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2989373-83-1C23H28N2O4
tert-Butyl 4-(3'-fluoro-5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C22H25FN2O3, CAS 2990524-14-4
tert-Butyl 4-(3'-fluoro-5-formyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2990524-14-4C22H25FN2O3
tert-Butyl 4-(5-formyl-3'-(trifluoromethoxy)-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H25F3N2O4, CAS 2990894-67-0
tert-Butyl 4-(5-formyl-3'-(trifluoromethoxy)-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2990894-67-0C23H25F3N2O4
tert-Butyl 4-(5-formyl-4'-methyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H28N2O3, CAS 2989085-19-8
tert-Butyl 4-(5-formyl-4'-methyl-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2989085-19-8C23H28N2O3
tert-Butyl 4-(5-formyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H25F3N2O3, CAS 2988190-84-5
tert-Butyl 4-(5-formyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2988190-84-5C23H25F3N2O3
tert-Butyl 4-(5-formyl-4'-methoxy-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate chemical structure, C23H28N2O4, CAS 2990093-50-8
tert-Butyl 4-(5-formyl-4'-methoxy-[1,1'-biphenyl]-2-yl)piperazine-1-carboxylate
CAS 2990093-50-8C23H28N2O4