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Murcko scaffold

Ring system with 3 rings and 18 atoms

125 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
125
With full pages
39
Scaffold SMILES

c1ccc(-c2cncnc2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cncnc2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 125 chemicals

2-[2-Amino-5-(4-methoxyphenyl)pyrimidin-4-yl]phenol chemical structure, C17H15N3O2, CAS 87538-71-4
2-[2-Amino-5-(4-methoxyphenyl)pyrimidin-4-yl]phenol
CAS 87538-71-4C17H15N3O2
2-(2-Amino-5-(4-methoxyphenyl)pyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol chemical structure, C21H21N3O3, CAS 849921-02-4
2-(2-Amino-5-(4-methoxyphenyl)pyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol
CAS 849921-02-4C21H21N3O3
2-[2-Amino-5-(3,4-dimethoxyphenyl)-6-methylpyrimidin-4-yl]-5-ethoxyphenol chemical structure, C21H23N3O4, CAS 850826-56-1
2-[2-Amino-5-(3,4-dimethoxyphenyl)-6-methylpyrimidin-4-yl]-5-ethoxyphenol
CAS 850826-56-1C21H23N3O4
2-[2-Amino-5-(4-methoxyphenyl)pyrimidin-4-yl]-5-methoxyphenol chemical structure, C18H17N3O3, CAS 87538-73-6
2-[2-Amino-5-(4-methoxyphenyl)pyrimidin-4-yl]-5-methoxyphenol
CAS 87538-73-6C18H17N3O3
5-Ethoxy-2-[5-(4-methoxyphenyl)pyrimidin-4-yl]phenol chemical structure, C19H18N2O3, CAS 877787-27-4
5-Ethoxy-2-[5-(4-methoxyphenyl)pyrimidin-4-yl]phenol
CAS 877787-27-4C19H18N2O3
2-(2-Amino-5-phenylpyrimidin-4-yl)-5-ethoxyphenol chemical structure, C18H17N3O2, CAS 896834-39-2
2-(2-Amino-5-phenylpyrimidin-4-yl)-5-ethoxyphenol
CAS 896834-39-2C18H17N3O2
2-(2-Amino-5-phenylpyrimidin-4-yl)-5-methoxyphenol chemical structure, C17H15N3O2, CAS 105258-11-5
2-(2-Amino-5-phenylpyrimidin-4-yl)-5-methoxyphenol
CAS 105258-11-5C17H15N3O2
5-Methoxy-2-(5-phenylpyrimidin-4-yl)phenol chemical structure, C17H14N2O2, CAS 105258-25-1
5-Methoxy-2-(5-phenylpyrimidin-4-yl)phenol
CAS 105258-25-1C17H14N2O2
2-(2-Amino-5-(4-bromophenyl)pyrimidin-4-yl)-5-methoxyphenol chemical structure, C17H14BrN3O2, CAS 105258-12-6
2-(2-Amino-5-(4-bromophenyl)pyrimidin-4-yl)-5-methoxyphenol
CAS 105258-12-6C17H14BrN3O2
2-(2-Amino-5-(4-methoxyphenyl)pyrimidin-4-yl)-4-ethyl-5-methoxyphenol chemical structure, C20H21N3O3, CAS 314247-66-0
2-(2-Amino-5-(4-methoxyphenyl)pyrimidin-4-yl)-4-ethyl-5-methoxyphenol
CAS 314247-66-0C20H21N3O3
5-Methoxy-2-(5-(4-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-4-yl)phenol chemical structure, C19H15F3N2O3, CAS 849914-00-7
5-Methoxy-2-(5-(4-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-4-yl)phenol
CAS 849914-00-7C19H15F3N2O3
5-Methoxy-2-[5-(4-methoxyphenyl)pyrimidin-4-yl]phenol chemical structure, C18H16N2O3, CAS 849919-15-9
5-Methoxy-2-[5-(4-methoxyphenyl)pyrimidin-4-yl]phenol
CAS 849919-15-9C18H16N2O3
2-(5-(2-Methoxyphenyl)pyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol chemical structure, C21H20N2O3, CAS 849920-52-1
2-(5-(2-Methoxyphenyl)pyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol
CAS 849920-52-1C21H20N2O3
2-(2-Amino-5-phenyl-6-(trifluoromethyl)pyrimidin-4-yl)-5-methoxyphenol chemical structure, C18H14F3N3O2, CAS 105258-17-1
2-(2-Amino-5-phenyl-6-(trifluoromethyl)pyrimidin-4-yl)-5-methoxyphenol
CAS 105258-17-1C18H14F3N3O2
2-[2-Amino-5-(4-bromophenyl)-6-methylpyrimidin-4-yl]-4-hexyl-5-methoxyphenol chemical structure, C24H28BrN3O2, CAS 105258-21-7
2-[2-Amino-5-(4-bromophenyl)-6-methylpyrimidin-4-yl]-4-hexyl-5-methoxyphenol
CAS 105258-21-7C24H28BrN3O2
5-Methoxy-2-(2-methyl-5-phenylpyrimidin-4-yl)phenol chemical structure, C18H16N2O2, CAS 899411-69-9
5-Methoxy-2-(2-methyl-5-phenylpyrimidin-4-yl)phenol
CAS 899411-69-9C18H16N2O2
2-(2-Amino-5-(2-methoxyphenyl)pyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol chemical structure, C21H21N3O3, CAS 850228-85-2
2-(2-Amino-5-(2-methoxyphenyl)pyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol
CAS 850228-85-2C21H21N3O3
2-(2-Amino-5-(4-bromophenyl)-6-(trifluoromethyl)pyrimidin-4-yl)-4-ethyl-5-methoxyphenol chemical structure, C20H17BrF3N3O2, CAS 304880-29-3
2-(2-Amino-5-(4-bromophenyl)-6-(trifluoromethyl)pyrimidin-4-yl)-4-ethyl-5-methoxyphenol
CAS 304880-29-3C20H17BrF3N3O2
2-[5-(4-Chlorophenyl)-2-methylpyrimidin-4-yl]-5-methoxyphenol chemical structure, C18H15ClN2O2, CAS 678189-82-7
2-[5-(4-Chlorophenyl)-2-methylpyrimidin-4-yl]-5-methoxyphenol
CAS 678189-82-7C18H15ClN2O2
2-[2-Amino-5-(4-chlorophenyl)-6-(trifluoromethyl)pyrimidin-4-yl]-5-ethoxyphenol chemical structure, C19H15ClF3N3O2, CAS 900288-69-9
2-[2-Amino-5-(4-chlorophenyl)-6-(trifluoromethyl)pyrimidin-4-yl]-5-ethoxyphenol
CAS 900288-69-9C19H15ClF3N3O2
2-(2-Amino-5-(4-chlorophenyl)pyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol chemical structure, C20H18ClN3O2, CAS 850239-49-5
2-(2-Amino-5-(4-chlorophenyl)pyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol
CAS 850239-49-5C20H18ClN3O2
5-Ethoxy-2-[5-(2-methoxyphenyl)pyrimidin-4-yl]phenol chemical structure, C19H18N2O3, CAS 850242-43-2
5-Ethoxy-2-[5-(2-methoxyphenyl)pyrimidin-4-yl]phenol
CAS 850242-43-2C19H18N2O3
2-(2-Amino-5-(2-methoxyphenyl)pyrimidin-4-yl)-5-ethoxyphenol chemical structure, C19H19N3O3, CAS 850243-63-9
2-(2-Amino-5-(2-methoxyphenyl)pyrimidin-4-yl)-5-ethoxyphenol
CAS 850243-63-9C19H19N3O3
2-(2-Amino-5-(4-methoxyphenyl)-6-methylpyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol chemical structure, C22H23N3O3, CAS 850728-98-2
2-(2-Amino-5-(4-methoxyphenyl)-6-methylpyrimidin-4-yl)-5-((2-methylallyl)oxy)phenol
CAS 850728-98-2C22H23N3O3