CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

39 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
39
With full pages
3
Scaffold SMILES

c1ccc(Nc2ccnc(-n3cccn3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ccnc(-n3cccn3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

2-(3,5-Dimethyl-1H-pyrazol-1-yl)-N-(4-ethoxyphenyl)-6-methylpyrimidin-4-amine chemical structure, C18H21N5O, CAS 312310-46-6
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-N-(4-ethoxyphenyl)-6-methylpyrimidin-4-amine
CAS 312310-46-6C18H21N5O
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-N-(4-methoxyphenyl)-6-methylpyrimidin-4-amine chemical structure, C17H19N5O, CAS 302789-07-7
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-N-(4-methoxyphenyl)-6-methylpyrimidin-4-amine
CAS 302789-07-7C17H19N5O
N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine chemical structure, C16H16ClN5, CAS 73029-78-4
N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine
CAS 73029-78-4C16H16ClN5
Ethyl 4-[(2,4-difluorophenyl)amino]-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine-5-carboxylate chemical structure, C18H17F2N5O2, CAS 1002539-18-5
Ethyl 4-[(2,4-difluorophenyl)amino]-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine-5-carboxylate
CAS 1002539-18-5C18H17F2N5O2
2-(3,5-Dimethyl-1-pyrazolyl)-4-(4-hydroxyanilino)-5-pyrimidinecarboxylic acid ethyl ester chemical structure, C18H19N5O3, CAS 958983-98-7
2-(3,5-Dimethyl-1-pyrazolyl)-4-(4-hydroxyanilino)-5-pyrimidinecarboxylic acid ethyl ester
CAS 958983-98-7C18H19N5O3
Ethyl 4-[(3,5-dichlorophenyl)amino]-2-(4-methyl-1H-pyrazol-1-yl)pyrimidine-5-carboxylate chemical structure, C17H15Cl2N5O2, CAS 1003988-71-3
Ethyl 4-[(3,5-dichlorophenyl)amino]-2-(4-methyl-1H-pyrazol-1-yl)pyrimidine-5-carboxylate
CAS 1003988-71-3C17H15Cl2N5O2
Ethyl 4-[(3,4-dimethylphenyl)amino]-2-(4-methyl-1H-pyrazol-1-yl)-5-pyrimidinecarboxylate chemical structure, C19H21N5O2, CAS 1002414-60-9
Ethyl 4-[(3,4-dimethylphenyl)amino]-2-(4-methyl-1H-pyrazol-1-yl)-5-pyrimidinecarboxylate
CAS 1002414-60-9C19H21N5O2
Ethyl 2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-[(4-methoxy-2-nitrophenyl)amino]pyrimidine-5-carboxylate chemical structure, C19H20N6O5, CAS 1010862-78-8
Ethyl 2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-[(4-methoxy-2-nitrophenyl)amino]pyrimidine-5-carboxylate
CAS 1010862-78-8C19H20N6O5
N-(3-Chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methyl-pyrimidin-4-amine chemical structure, C16H16ClN5, CAS 1019106-82-1
N-(3-Chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methyl-pyrimidin-4-amine
CAS 1019106-82-1C16H16ClN5
6-Methyl-N-(3-methylphenyl)-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C15H14N6O2, CAS 904826-39-7
6-Methyl-N-(3-methylphenyl)-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 904826-39-7C15H14N6O2
N-(4-Ethoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C16H16N6O3, CAS 1001502-64-2
N-(4-Ethoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1001502-64-2C16H16N6O3
N-(4-Fluorophenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C14H11FN6O2, CAS 904826-25-1
N-(4-Fluorophenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 904826-25-1C14H11FN6O2
N-(3-Chloro-4-fluorophenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C14H10ClFN6O2, CAS 1002044-04-3
N-(3-Chloro-4-fluorophenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1002044-04-3C14H10ClFN6O2
N-(3-Chloro-4-methoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C15H13ClN6O3, CAS 1002214-67-6
N-(3-Chloro-4-methoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1002214-67-6C15H13ClN6O3
Ethyl 4-[[6-methyl-2-(4-nitropyrazol-1-yl)pyrimidin-4-yl]amino]benzoate chemical structure, C17H16N6O4, CAS 1001829-93-1
Ethyl 4-[[6-methyl-2-(4-nitropyrazol-1-yl)pyrimidin-4-yl]amino]benzoate
CAS 1001829-93-1C17H16N6O4
N-(3-Methoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C15H14N6O3, CAS 1001831-70-4
N-(3-Methoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1001831-70-4C15H14N6O3
N-(4-Butylphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C18H20N6O2, CAS 1001832-07-0
N-(4-Butylphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1001832-07-0C18H20N6O2
N-(2-Methoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C15H14N6O3, CAS 1002041-58-8
N-(2-Methoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1002041-58-8C15H14N6O3
N-(4-Methoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C15H14N6O3, CAS 1002041-75-9
N-(4-Methoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1002041-75-9C15H14N6O3
N-(4-Chlorophenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C14H11ClN6O2, CAS 1002042-13-8
N-(4-Chlorophenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1002042-13-8C14H11ClN6O2
N-(3-Chloro-4-methylphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C15H13ClN6O2, CAS 1002042-87-6
N-(3-Chloro-4-methylphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1002042-87-6C15H13ClN6O2
N-(3,4-Dimethoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C16H16N6O4, CAS 1002043-04-0
N-(3,4-Dimethoxyphenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1002043-04-0C16H16N6O4
N-(3-Chlorophenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C14H11ClN6O2, CAS 1001607-57-3
N-(3-Chlorophenyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1001607-57-3C14H11ClN6O2
N-Ethyl-6-methyl-N-(3-methylphenyl)-2-(4-nitropyrazol-1-yl)pyrimidin-4-amine chemical structure, C17H18N6O2, CAS 1001608-03-2
N-Ethyl-6-methyl-N-(3-methylphenyl)-2-(4-nitropyrazol-1-yl)pyrimidin-4-amine
CAS 1001608-03-2C17H18N6O2