CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

35 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
35
With full pages
6
Scaffold SMILES

c1cc(N2CCNCC2)ncc1B1OCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(N2CCNCC2)ncc1B1OCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

1-Methyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine chemical structure, C16H26BN3O2, CAS 918524-63-7
1-Methyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine
CAS 918524-63-7C16H26BN3O2
2-(Piperazin-1-yl)pyridine-5-boronic acid, pinacol ester chemical structure, C15H24BN3O2, CAS 871125-86-9
2-(Piperazin-1-yl)pyridine-5-boronic acid, pinacol ester
CAS 871125-86-9C15H24BN3O2
tert-Butyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate chemical structure, C20H32BN3O4, CAS 496786-98-2
tert-Butyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate
CAS 496786-98-2C20H32BN3O4
1-Methyl-4-(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine chemical structure, C17H28BN3O2, CAS 1191062-86-8
1-Methyl-4-(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine
CAS 1191062-86-8C17H28BN3O2
1-(4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazin-1-yl)ethanone chemical structure, C17H26BN3O3, CAS 1073372-01-6
1-(4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazin-1-yl)ethanone
CAS 1073372-01-6C17H26BN3O3
Ethyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate chemical structure, C18H28BN3O4, CAS 1073354-26-3
Ethyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate
CAS 1073354-26-3C18H28BN3O4
tert-Butyl 4-(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate chemical structure, C21H34BN3O4, CAS 1073354-54-7
tert-Butyl 4-(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate
CAS 1073354-54-7C21H34BN3O4
2-(4-Boc-piperazin-1-yl)-4-methylpyridine-5-boronic acid pinacol ester chemical structure, C21H34BN3O4, CAS 1073355-13-1
2-(4-Boc-piperazin-1-yl)-4-methylpyridine-5-boronic acid pinacol ester
CAS 1073355-13-1C21H34BN3O4
2-(4-Trifluoroacetylpiperazino)pyridine-5-boronic acid, pinacol ester chemical structure, C17H23BF3N3O3, CAS 1218789-87-7
2-(4-Trifluoroacetylpiperazino)pyridine-5-boronic acid, pinacol ester
CAS 1218789-87-7C17H23BF3N3O3
1-(3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)-4-methylpiperazine chemical structure, C16H25BClN3O2, CAS 2096334-60-8
1-(3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)-4-methylpiperazine
CAS 2096334-60-8C16H25BClN3O2
1-Ethyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine chemical structure, C17H28BN3O2, CAS 940285-00-7
1-Ethyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine
CAS 940285-00-7C17H28BN3O2
tert-Butyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxylate chemical structure, C21H31BF3N3O4, CAS 1246372-73-5
tert-Butyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxylate
CAS 1246372-73-5C21H31BF3N3O4
1-Methyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine trihydrochloride chemical structure, C16H29BCl3N3O2, CAS 1452551-40-4
1-Methyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine trihydrochloride
CAS 1452551-40-4C16H29BCl3N3O2
1-[4-Methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine chemical structure, C16H26BN3O2, CAS 2377607-17-3
1-[4-Methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine
CAS 2377607-17-3C16H26BN3O2
1-[6-Methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine hydrochloride chemical structure, C16H27BClN3O2, CAS 2377609-42-0
1-[6-Methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine hydrochloride
CAS 2377609-42-0C16H27BClN3O2
(4-(4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazin-1-yl)methanol chemical structure, C17H28BN3O3, CAS 1352414-63-1
(4-(4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazin-1-yl)methanol
CAS 1352414-63-1C17H28BN3O3
1-Ethyl-4-(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine chemical structure, C18H30BN3O2, CAS 1351380-80-7
1-Ethyl-4-(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine
CAS 1351380-80-7C18H30BN3O2
2-(4-(4-Methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl)piperazin-1-yl)ethanol chemical structure, C18H30BN3O3, CAS 1352135-92-2
2-(4-(4-Methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl)piperazin-1-yl)ethanol
CAS 1352135-92-2C18H30BN3O3
2-(4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazin-1-yl)ethanamine chemical structure, C17H29BN4O2, CAS 1489230-58-1
2-(4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazin-1-yl)ethanamine
CAS 1489230-58-1C17H29BN4O2
1-(1-Methylethyl)-4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine chemical structure, C18H30BN3O2, CAS 919496-58-5
1-(1-Methylethyl)-4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine
CAS 919496-58-5C18H30BN3O2
1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine hydrochloride chemical structure, C15H25BClN3O2, CAS 2222758-60-1
1-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine hydrochloride
CAS 2222758-60-1C15H25BClN3O2
(3R,5S)-3,5-Dimethyl-1-[4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine chemical structure, C18H30BN3O2, CAS 1884331-97-8
(3R,5S)-3,5-Dimethyl-1-[4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine
CAS 1884331-97-8C18H30BN3O2
1-(3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine chemical structure, C15H23BFN3O2, CAS 1351392-29-4
1-(3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine
CAS 1351392-29-4C15H23BFN3O2
tert-Butyl 4-(6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate chemical structure, C21H34BN3O4, CAS 1447764-87-5
tert-Butyl 4-(6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine-1-carboxylate
CAS 1447764-87-5C21H34BN3O4