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Murcko scaffold

Ring system with 3 rings and 19 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
17
With full pages
8
Scaffold SMILES

O=C1CC(N2CCN(c3ccccc3)CC2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(N2CCN(c3ccccc3)CC2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

3-[4-(4-Chlorophenyl)piperazin-1-yl]-1-methylpyrrolidine-2,5-dione chemical structure, C15H18ClN3O2, CAS 299949-34-1
3-[4-(4-Chlorophenyl)piperazin-1-yl]-1-methylpyrrolidine-2,5-dione
CAS 299949-34-1C15H18ClN3O2
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-methylpyrrolidine-2,5-dione chemical structure, C15H18FN3O2, CAS 299949-38-5
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-methylpyrrolidine-2,5-dione
CAS 299949-38-5C15H18FN3O2
3-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-methylpyrrolidine-2,5-dione chemical structure, C16H21N3O3, CAS 299949-39-6
3-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-methylpyrrolidine-2,5-dione
CAS 299949-39-6C16H21N3O3
3-[4-(4-Chlorophenyl)piperazin-1-yl]-1-ethylpyrrolidine-2,5-dione chemical structure, C16H20ClN3O2, CAS 351437-30-4
3-[4-(4-Chlorophenyl)piperazin-1-yl]-1-ethylpyrrolidine-2,5-dione
CAS 351437-30-4C16H20ClN3O2
3-[4-(4-Methoxyphenyl)piperazin-1-yl]-1-methylpyrrolidine-2,5-dione chemical structure, C16H21N3O3, CAS 350707-97-0
3-[4-(4-Methoxyphenyl)piperazin-1-yl]-1-methylpyrrolidine-2,5-dione
CAS 350707-97-0C16H21N3O3
1-Ethyl-3-(4-phenylpiperazin-1-yl)pyrrolidine-2,5-dione chemical structure, C16H21N3O2, CAS 385419-41-0
1-Ethyl-3-(4-phenylpiperazin-1-yl)pyrrolidine-2,5-dione
CAS 385419-41-0C16H21N3O2
1-Ethyl-3-[4-(3-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione chemical structure, C17H23N3O3, CAS 590379-43-4
1-Ethyl-3-[4-(3-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione
CAS 590379-43-4C17H23N3O3
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-propylpyrrolidine-2,5-dione chemical structure, C17H22FN3O2, CAS 857494-27-0
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-propylpyrrolidine-2,5-dione
CAS 857494-27-0C17H22FN3O2
1-Butyl-3-[4-(4-fluorophenyl)piperazin-1-yl]pyrrolidine-2,5-dione chemical structure, C18H24FN3O2, CAS 857494-25-8
1-Butyl-3-[4-(4-fluorophenyl)piperazin-1-yl]pyrrolidine-2,5-dione
CAS 857494-25-8C18H24FN3O2
3-[4-(4-Fluorophenyl)piperazin-1-yl]-1-(2-methoxyethyl)pyrrolidine-2,5-dione chemical structure, C17H22FN3O3, CAS 857494-28-1
3-[4-(4-Fluorophenyl)piperazin-1-yl]-1-(2-methoxyethyl)pyrrolidine-2,5-dione
CAS 857494-28-1C17H22FN3O3
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-isopropylpyrrolidine-2,5-dione chemical structure, C17H22FN3O2, CAS 857494-24-7
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-isopropylpyrrolidine-2,5-dione
CAS 857494-24-7C17H22FN3O2
3-[4-(4-Fluorophenyl)piperazin-1-yl]pyrrolidine-2,5-dione chemical structure, C14H16FN3O2, CAS 857494-23-6
3-[4-(4-Fluorophenyl)piperazin-1-yl]pyrrolidine-2,5-dione
CAS 857494-23-6C14H16FN3O2
1-Methyl-3-(4-phenylpiperazin-1-yl)pyrrolidine-2,5-dione chemical structure, C15H19N3O2, CAS 313378-65-3
1-Methyl-3-(4-phenylpiperazin-1-yl)pyrrolidine-2,5-dione
CAS 313378-65-3C15H19N3O2
3-[4-(3,4-Dichlorophenyl)piperazin-1-yl]pyrrolidine-2,5-dione chemical structure, C14H15Cl2N3O2, CAS 350707-99-2
3-[4-(3,4-Dichlorophenyl)piperazin-1-yl]pyrrolidine-2,5-dione
CAS 350707-99-2C14H15Cl2N3O2
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-isobutylpyrrolidine-2,5-dione chemical structure, C18H24FN3O2, CAS 881485-25-2
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-isobutylpyrrolidine-2,5-dione
CAS 881485-25-2C18H24FN3O2
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-(3-methoxypropyl)pyrrolidine-2,5-dione chemical structure, C18H24FN3O3, CAS 924865-49-6
3-(4-(4-Fluorophenyl)piperazin-1-yl)-1-(3-methoxypropyl)pyrrolidine-2,5-dione
CAS 924865-49-6C18H24FN3O3
3-(4-Phenylpiperazin-1-yl)-1-propylpyrrolidine-2,5-dione chemical structure, C17H23N3O2, CAS 924861-22-3
3-(4-Phenylpiperazin-1-yl)-1-propylpyrrolidine-2,5-dione
CAS 924861-22-3C17H23N3O2