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Murcko scaffold

Ring system with 3 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
10
With full pages
6
Scaffold SMILES

c1ccc(N2CCN(c3nc[nH]n3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(N2CCN(c3nc[nH]n3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

3-[4-(3-Chlorophenyl)piperazino]-1H-1,2,4-triazol-5-amine chemical structure, C12H15ClN6, CAS 865657-91-6
3-[4-(3-Chlorophenyl)piperazino]-1H-1,2,4-triazol-5-amine
CAS 865657-91-6C12H15ClN6
5-[4-(4-Chlorophenyl)piperazino]-1H-1,2,4-triazol-3-amine chemical structure, C12H15ClN6, CAS 339021-20-4
5-[4-(4-Chlorophenyl)piperazino]-1H-1,2,4-triazol-3-amine
CAS 339021-20-4C12H15ClN6
5-[4-(2,6-Dimethylphenyl)piperazino]-1H-1,2,4-triazol-3-amine chemical structure, C14H20N6, CAS 339021-23-7
5-[4-(2,6-Dimethylphenyl)piperazino]-1H-1,2,4-triazol-3-amine
CAS 339021-23-7C14H20N6
5-[4-(4-Methoxyphenyl)-1-piperazinyl]-1H-1,2,4-triazol-3-amine chemical structure, C13H18N6O, CAS 339021-27-1
5-[4-(4-Methoxyphenyl)-1-piperazinyl]-1H-1,2,4-triazol-3-amine
CAS 339021-27-1C13H18N6O
5-[4-(2-Chlorophenyl)piperazino]-1H-1,2,4-triazol-3-amine chemical structure, C12H15ClN6, CAS 400087-40-3
5-[4-(2-Chlorophenyl)piperazino]-1H-1,2,4-triazol-3-amine
CAS 400087-40-3C12H15ClN6
5-(4-Phenyl-1-piperazinyl)-1H-1,2,4-triazol-3-amine chemical structure, C12H16N6, CAS 118630-19-6
5-(4-Phenyl-1-piperazinyl)-1H-1,2,4-triazol-3-amine
CAS 118630-19-6C12H16N6
3-[4-(4-Fluorophenyl)piperazin-1-yl]-1H-1,2,4-triazol-5-amine chemical structure, C12H15FN6, CAS 118630-21-0
3-[4-(4-Fluorophenyl)piperazin-1-yl]-1H-1,2,4-triazol-5-amine
CAS 118630-21-0C12H15FN6
5-[4-(4-Fluorophenyl)piperazino]-1-methyl-1H-1,2,4-triazol-3-amine chemical structure, C13H17FN6, CAS 241127-34-4
5-[4-(4-Fluorophenyl)piperazino]-1-methyl-1H-1,2,4-triazol-3-amine
CAS 241127-34-4C13H17FN6
1-Methyl-5-{4-[3-(trifluoromethyl)phenyl]piperazino}-1H-1,2,4-triazol-3-amine chemical structure, C14H17F3N6, CAS 241488-12-0
1-Methyl-5-{4-[3-(trifluoromethyl)phenyl]piperazino}-1H-1,2,4-triazol-3-amine
CAS 241488-12-0C14H17F3N6
5-[4-(4-Nitrophenyl)piperazino]-1H-1,2,4-triazol-3-amine chemical structure, C12H15N7O2, CAS 339021-30-6
5-[4-(4-Nitrophenyl)piperazino]-1H-1,2,4-triazol-3-amine
CAS 339021-30-6C12H15N7O2