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Murcko scaffold

2-(4-Phenylpiperazin-1-yl)thiazole scaffold

26 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 17
Chemicals: 26
With full pages: 4

Scaffold SMILES

c1ccc(N2CCN(c3nccs3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(4-Phenylpiperazin-1-yl)thiazole page

Murcko scaffold c1ccc(N2CCN(c3nccs3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2-(4-Phenylpiperazin-1-yl)-1,3-thiazole-5-carbaldehyde chemical structure, C14H15N3OS, CAS 303987-39-5

2-(4-Phenylpiperazin-1-yl)-1,3-thiazole-5-carbaldehyde

CAS 303987-39-5C₁₄H₁₅N₃OS

Methyl 4-amino-2-[4-(4-chlorophenyl)piperazino]-1,3-thiazole-5-carboxylate chemical structure, C15H17ClN4O2S, CAS 343375-62-2

Methyl 4-amino-2-[4-(4-chlorophenyl)piperazino]-1,3-thiazole-5-carboxylate

CAS 343375-62-2C₁₅H₁₇ClN₄O₂S

2-{[2-(4-Phenylpiperazino)-1,3-thiazol-5-yl]methylene}malononitrile chemical structure, C17H15N5S, CAS 477868-64-7

2-{[2-(4-Phenylpiperazino)-1,3-thiazol-5-yl]methylene}malononitrile

CAS 477868-64-7C₁₇H₁₅N₅S

2-(4-Phenylpiperazino)-1,3-thiazole-5-carbaldehyde oxime chemical structure, C14H16N4OS, CAS 477886-90-1

2-(4-Phenylpiperazino)-1,3-thiazole-5-carbaldehyde oxime

CAS 477886-90-1C₁₄H₁₆N₄OS

Methyl 2-[4-(4-chlorophenyl)piperazino]-4-{[(dimethylamino)methylene]amino}-1,3-thiazole-5-carboxylate chemical structure, C18H22ClN5O2S, CAS 343375-63-3

Methyl 2-[4-(4-chlorophenyl)piperazino]-4-{[(dimethylamino)methylene]amino}-1,3-thiazole-5-carboxylate

CAS 343375-63-3C₁₈H₂₂ClN₅O₂S

Ethyl 4-amino-2-(4-phenylpiperazin-1-yl)-1,3-thiazole-5-carboxylate chemical structure, C16H20N4O2S, CAS 871558-59-7

Ethyl 4-amino-2-(4-phenylpiperazin-1-yl)-1,3-thiazole-5-carboxylate

CAS 871558-59-7C₁₆H₂₀N₄O₂S

1-(2-Chlorophenyl)-4-(1,3-thiazol-2-yl)piperazine chemical structure, C13H14ClN3S, CAS 2324658-88-8

1-(2-Chlorophenyl)-4-(1,3-thiazol-2-yl)piperazine

CAS 2324658-88-8C₁₃H₁₄ClN₃S

1-(2-Fluorophenyl)-4-(1,3-thiazol-2-yl)piperazine chemical structure, C13H14FN3S, CAS 2326081-17-6

1-(2-Fluorophenyl)-4-(1,3-thiazol-2-yl)piperazine

CAS 2326081-17-6C₁₃H₁₄FN₃S

2-[4-(2-Thiazolyl)-1-piperazinyl]benzenamine chemical structure, C13H16N4S, CAS 1016740-71-8

2-[4-(2-Thiazolyl)-1-piperazinyl]benzenamine

CAS 1016740-71-8C₁₃H₁₆N₄S

2-(4-Phenylpiperazin-1-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C14H15N3O2S, CAS 952182-67-1

2-(4-Phenylpiperazin-1-yl)-1,3-thiazole-4-carboxylic acid

CAS 952182-67-1C₁₄H₁₅N₃O₂S

5-Bromo-2-[4-(2-thiazolyl)-1-piperazinyl]benzenamine chemical structure, C13H15BrN4S, CAS 1017030-89-5

5-Bromo-2-[4-(2-thiazolyl)-1-piperazinyl]benzenamine

CAS 1017030-89-5C₁₃H₁₅BrN₄S

Benzenamine, 2-methyl-4-[4-(2-thiazolyl)-1-piperazinyl]- chemical structure, C14H18N4S, CAS 1154319-52-4

Benzenamine, 2-methyl-4-[4-(2-thiazolyl)-1-piperazinyl]-

CAS 1154319-52-4C₁₄H₁₈N₄S

4-Chloro-2-(4-phenylpiperazin-1-yl)thiazole-5-carbaldehyde chemical structure, C14H14ClN3OS, CAS 1263215-16-2

4-Chloro-2-(4-phenylpiperazin-1-yl)thiazole-5-carbaldehyde

CAS 1263215-16-2C₁₄H₁₄ClN₃OS

2-(4-Phenylpiperazin-1-yl)thiazole chemical structure, C13H15N3S, CAS 1789594-90-6

2-(4-Phenylpiperazin-1-yl)thiazole

CAS 1789594-90-6C₁₃H₁₅N₃S

5-Thiazolemethanol, 2-[4-(2-chlorophenyl)-1-piperazinyl]- chemical structure, C14H16ClN3OS, CAS 1487824-35-0

5-Thiazolemethanol, 2-[4-(2-chlorophenyl)-1-piperazinyl]-

CAS 1487824-35-0C₁₄H₁₆ClN₃OS

2-Fluoro-3-[4-(2-thiazolyl)-1-piperazinyl]benzenemethanol chemical structure, C14H16FN3OS, CAS 1400758-81-7

2-Fluoro-3-[4-(2-thiazolyl)-1-piperazinyl]benzenemethanol

CAS 1400758-81-7C₁₄H₁₆FN₃OS

2-[4-(4-Methylphenyl)piperazin-1-yl]-1,3-thiazole-4-carboxylic acid chemical structure, C15H17N3O2S, CAS 1706455-85-7

2-[4-(4-Methylphenyl)piperazin-1-yl]-1,3-thiazole-4-carboxylic acid

CAS 1706455-85-7C₁₅H₁₇N₃O₂S

1-Phenyl-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine chemical structure, C14H14F3N3S, CAS 2770604-46-9

1-Phenyl-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine

CAS 2770604-46-9C₁₄H₁₄F₃N₃S

1-(2-Methoxyphenyl)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine chemical structure, C15H16F3N3OS, CAS 2742029-83-8

1-(2-Methoxyphenyl)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine

CAS 2742029-83-8C₁₅H₁₆F₃N₃OS

1-(2-Methylphenyl)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine chemical structure, C15H16F3N3S, CAS 2770583-38-3

1-(2-Methylphenyl)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine

CAS 2770583-38-3C₁₅H₁₆F₃N₃S

1-(4-Methoxyphenyl)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine hydrobromide chemical structure, C15H17BrF3N3OS, CAS 1029988-93-9

1-(4-Methoxyphenyl)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine hydrobromide

CAS 1029988-93-9C₁₅H₁₇BrF₃N₃OS

1-(2-Methoxyphenyl)-4-(5-methyl-1,3-thiazol-2-yl)piperazine chemical structure, C15H19N3OS, CAS 2742054-08-4

1-(2-Methoxyphenyl)-4-(5-methyl-1,3-thiazol-2-yl)piperazine

CAS 2742054-08-4C₁₅H₁₉N₃OS

1-(2,3-Dimethylphenyl)-4-(1,3-thiazol-2-yl)piperazine chemical structure, C15H19N3S, CAS 2640976-39-0

1-(2,3-Dimethylphenyl)-4-(1,3-thiazol-2-yl)piperazine

CAS 2640976-39-0C₁₅H₁₉N₃S

1-(2,3-Dimethylphenyl)-4-(5-methyl-1,3-thiazol-2-yl)piperazine chemical structure, C16H21N3S, CAS 2640961-20-0

1-(2,3-Dimethylphenyl)-4-(5-methyl-1,3-thiazol-2-yl)piperazine

CAS 2640961-20-0C₁₆H₂₁N₃S