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Murcko scaffold

Ring system with 3 rings and 14 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
18
With full pages
9
Scaffold SMILES

O=c1[nH]c(=O)c2c(nc3n2CCS3)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c(=O)c2c(nc3n2CCS3)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-Methyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C8H8N4O2S, CAS 178452-87-4
1-Methyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 178452-87-4C8H8N4O2S
3-Allyl-1-methyl-6,7-dihydro-1H-thiazolo[2,3-f]purine-2,4-dione chemical structure, C11H12N4O2S, CAS 312915-44-9
3-Allyl-1-methyl-6,7-dihydro-1H-thiazolo[2,3-f]purine-2,4-dione
CAS 312915-44-9C11H12N4O2S
(1-Methyl-2,4-dioxo-1,4,6,7-tetrahydro[1,3]thiazolo[2,3-f]purin-3(2H)-yl)acetic acid chemical structure, C10H10N4O4S, CAS 178452-80-7
(1-Methyl-2,4-dioxo-1,4,6,7-tetrahydro[1,3]thiazolo[2,3-f]purin-3(2H)-yl)acetic acid
CAS 178452-80-7C10H10N4O4S
Ethyl (1-methyl-2,4-dioxo-1,4,6,7-tetrahydro[1,3]thiazolo[2,3-f]purin-3(2H)-yl)acetate chemical structure, C12H14N4O4S, CAS 313262-58-7
Ethyl (1-methyl-2,4-dioxo-1,4,6,7-tetrahydro[1,3]thiazolo[2,3-f]purin-3(2H)-yl)acetate
CAS 313262-58-7C12H14N4O4S
1-Methyl-3-(3-methyl-butyl)-6,7-dihydro-1H-thiazolo[2,3-f]purine-2,4-dione chemical structure, C13H18N4O2S, CAS 327170-50-3
1-Methyl-3-(3-methyl-butyl)-6,7-dihydro-1H-thiazolo[2,3-f]purine-2,4-dione
CAS 327170-50-3C13H18N4O2S
3-Ethyl-1-methyl-6,7-dihydrothiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C10H12N4O2S, CAS 313646-08-1
3-Ethyl-1-methyl-6,7-dihydrothiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 313646-08-1C10H12N4O2S
3-Isobutyl-1-methyl-6,7-dihydro-1H-thiazolo[2,3-f]purine-2,4-dione chemical structure, C12H16N4O2S, CAS 313528-25-5
3-Isobutyl-1-methyl-6,7-dihydro-1H-thiazolo[2,3-f]purine-2,4-dione
CAS 313528-25-5C12H16N4O2S
1-Methyl-3-propyl-6,7-dihydro-1H-thiazolo[2,3-f]purine-2,4-dione chemical structure, C11H14N4O2S, CAS 330818-20-7
1-Methyl-3-propyl-6,7-dihydro-1H-thiazolo[2,3-f]purine-2,4-dione
CAS 330818-20-7C11H14N4O2S
1,3-Dimethyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C9H10N4O2S, CAS 6048-97-1
1,3-Dimethyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 6048-97-1C9H10N4O2S
2-Heptyl-4-methyl-7,8-dihydropurino[8,7-b][1,3]thiazole-1,3-dione chemical structure, C15H22N4O2S, CAS 329700-40-5
2-Heptyl-4-methyl-7,8-dihydropurino[8,7-b][1,3]thiazole-1,3-dione
CAS 329700-40-5C15H22N4O2S
1-Methyl-3-octyl-6,7-dihydrothiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C16H24N4O2S, CAS 329700-88-1
1-Methyl-3-octyl-6,7-dihydrothiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 329700-88-1C16H24N4O2S
Thiazolo(2,3-f)purine-3(2H)-acetamide, 1,4,6,7-tetrahydro-N,N-bis(2-hydroxyethyl)-2,4-dioxo-1-methyl- chemical structure, C14H19N5O5S, CAS 178452-84-1
Thiazolo(2,3-f)purine-3(2H)-acetamide, 1,4,6,7-tetrahydro-N,N-bis(2-hydroxyethyl)-2,4-dioxo-1-methyl-
CAS 178452-84-1C14H19N5O5S
Thiazolo(2,3-f)purine-3(2H)-acetamide, 1,4,6,7-tetrahydro-N,N-diethyl-2,4-dioxo-1-methyl- chemical structure, C14H19N5O3S, CAS 178452-85-2
Thiazolo(2,3-f)purine-3(2H)-acetamide, 1,4,6,7-tetrahydro-N,N-diethyl-2,4-dioxo-1-methyl-
CAS 178452-85-2C14H19N5O3S
1-Methyl-3-pentyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C13H18N4O2S, CAS 313646-10-5
1-Methyl-3-pentyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 313646-10-5C13H18N4O2S
3-Decyl-1-methyl-6,7-dihydrothiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C18H28N4O2S, CAS 330818-21-8
3-Decyl-1-methyl-6,7-dihydrothiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 330818-21-8C18H28N4O2S
3-Hexyl-1-methyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C14H20N4O2S, CAS 329699-76-5
3-Hexyl-1-methyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 329699-76-5C14H20N4O2S
1-Methyl-3-nonyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C17H26N4O2S, CAS 321732-11-0
1-Methyl-3-nonyl-6,7-dihydro[1,3]thiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 321732-11-0C17H26N4O2S
6,7-Dihydro-3-methyl-1-(2-methylpropyl)thiazolo[2,3-f]purine-2,4(1H,3H)-dione chemical structure, C12H16N4O2S, CAS 382646-16-4
6,7-Dihydro-3-methyl-1-(2-methylpropyl)thiazolo[2,3-f]purine-2,4(1H,3H)-dione
CAS 382646-16-4C12H16N4O2S