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Murcko scaffold

1,5,6,7-Tetrahydro-4H-cyclopenta(4,5)thieno(2,3-d)pyrimidin-4-one scaffold

85 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 13
Chemicals: 85
With full pages: 31

Scaffold SMILES

O=c1[nH]cnc2sc3c(c12)CCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1,5,6,7-Tetrahydro-4H-cyclopenta(4,5)thieno(2,3-d)pyrimidin-4-one page

Murcko scaffold O=c1[nH]cnc2sc3c(c12)CCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 85 chemicals

1,5,6,7-Tetrahydro-4H-cyclopenta(4,5)thieno(2,3-d)pyrimidin-4-one chemical structure, C9H8N2OS, CAS 14346-25-9

1,5,6,7-Tetrahydro-4H-cyclopenta(4,5)thieno(2,3-d)pyrimidin-4-one

CAS 14346-25-9C₉H₈N₂OS

4H-Cyclopenta(4,5)thieno(2,3-d)pyrimidin-4-one, 3,5,6,7-tetrahydro-3-amino-2-methyl- chemical structure, C10H11N3OS, CAS 22721-36-4

4H-Cyclopenta(4,5)thieno(2,3-d)pyrimidin-4-one, 3,5,6,7-tetrahydro-3-amino-2-methyl-

CAS 22721-36-4C₁₀H₁₁N₃OS

2-Amino-1,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one chemical structure, C9H9N3OS, CAS 900475-21-0

2-Amino-1,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one

CAS 900475-21-0C₉H₉N₃OS

3-Amino-2-ethyl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one chemical structure, C11H13N3OS, CAS 342383-93-1

3-Amino-2-ethyl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one

CAS 342383-93-1C₁₁H₁₃N₃OS

2-Butyl-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ol chemical structure, C13H16N2OS, CAS 370074-90-1

2-Butyl-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-ol

CAS 370074-90-1C₁₃H₁₆N₂OS

2-((3-Ethyl-4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)propanoic acid chemical structure, C14H16N2O3S2, CAS 369607-52-3

2-((3-Ethyl-4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)propanoic acid

CAS 369607-52-3C₁₄H₁₆N₂O₃S₂

[(3-Ethyl-4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-D]pyrimid+ chemical structure, C13H14N2O3S2, CAS 314041-85-5

[(3-Ethyl-4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-D]pyrimid+

CAS 314041-85-5C₁₃H₁₄N₂O₃S₂

2-[[2-(2-Methylprop-2-enyl)-1-oxo-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl]sulfanyl]acetamide chemical structure, C15H17N3O2S2, CAS 351006-20-7

2-[[2-(2-Methylprop-2-enyl)-1-oxo-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl]sulfanyl]acetamide

CAS 351006-20-7C₁₅H₁₇N₃O₂S₂

3-Allyl-2-(methylsulfanyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one chemical structure, C13H14N2OS2, CAS 312626-06-5

3-Allyl-2-(methylsulfanyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one

CAS 312626-06-5C₁₃H₁₄N₂OS₂

2-(5-Allyl-4-oxo-2,3,4,5-tetrahydro-1H-8-thia-5,7-diaza-cyclopenta[a]inden-6-ylsulfanyl)-acetamide chemical structure, C14H15N3O2S2, CAS 499232-09-6

2-(5-Allyl-4-oxo-2,3,4,5-tetrahydro-1H-8-thia-5,7-diaza-cyclopenta[a]inden-6-ylsulfanyl)-acetamide

CAS 499232-09-6C₁₄H₁₅N₃O₂S₂

Methyl (4-oxo-6,7-dihydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-3(5H)-yl)acetate chemical structure, C12H12N2O3S, CAS 6727-78-2

Methyl (4-oxo-6,7-dihydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-3(5H)-yl)acetate

CAS 6727-78-2C₁₂H₁₂N₂O₃S

Ethyl 2-(4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-3-yl)acetate chemical structure, C13H14N2O3S, CAS 433702-79-5

Ethyl 2-(4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-3-yl)acetate

CAS 433702-79-5C₁₃H₁₄N₂O₃S

3-Amino-2-propyl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one chemical structure, C12H15N3OS, CAS 342383-92-0

3-Amino-2-propyl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one

CAS 342383-92-0C₁₂H₁₅N₃OS

5-Ethyl-6-ethylsulfanyl-1,2,3,5-tetrahydro-8-thia-5,7-diaza-cyclopenta[a]inden-4-one chemical structure, C13H16N2OS2, CAS 335220-88-7

5-Ethyl-6-ethylsulfanyl-1,2,3,5-tetrahydro-8-thia-5,7-diaza-cyclopenta[a]inden-4-one

CAS 335220-88-7C₁₃H₁₆N₂OS₂

2-(Dichloromethyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one chemical structure, C10H8Cl2N2OS, CAS 724745-65-7

2-(Dichloromethyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one

CAS 724745-65-7C₁₀H₈Cl₂N₂OS

(5-Methyl-4-oxo-2,3,4,5-tetrahydro-1H-8-thia-5,7-diaza-cyclopenta[a]inden-6-ylsulfanyl)-acetic acid chemical structure, C12H12N2O3S2, CAS 462067-18-1

(5-Methyl-4-oxo-2,3,4,5-tetrahydro-1H-8-thia-5,7-diaza-cyclopenta[a]inden-6-ylsulfanyl)-acetic acid

CAS 462067-18-1C₁₂H₁₂N₂O₃S₂

3-(2-Methyl-2-propenyl)-2-[(2-methyl-2-propenyl)sulfanyl]-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one chemical structure, C17H20N2OS2, CAS 351006-14-9

3-(2-Methyl-2-propenyl)-2-[(2-methyl-2-propenyl)sulfanyl]-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one

CAS 351006-14-9C₁₇H₂₀N₂OS₂

2-(Isopropylthio)-3-(2-methylallyl)-6,7-dihydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4(5H)-one chemical structure, C16H20N2OS2, CAS 351006-08-1

2-(Isopropylthio)-3-(2-methylallyl)-6,7-dihydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4(5H)-one

CAS 351006-08-1C₁₆H₂₀N₂OS₂

Cambridge id 5914922 chemical structure, C14H14N2O3S2, CAS 356587-36-5

Cambridge id 5914922

CAS 356587-36-5C₁₄H₁₄N₂O₃S₂

2-[(2-Ethyl-1-oxo-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl)sulfanyl]acetamide chemical structure, C13H15N3O2S2, CAS 368889-20-7

2-[(2-Ethyl-1-oxo-7,8-dihydro-6H-cyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl)sulfanyl]acetamide

CAS 368889-20-7C₁₃H₁₅N₃O₂S₂

Methyl [(4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate chemical structure, C12H12N2O3S2, CAS 370070-83-0

Methyl [(4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate

CAS 370070-83-0C₁₂H₁₂N₂O₃S₂

Ethyl [(3-ethyl-4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate chemical structure, C15H18N2O3S2, CAS 356587-47-8

Ethyl [(3-ethyl-4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate

CAS 356587-47-8C₁₅H₁₈N₂O₃S₂

Ethyl [(3-methyl-4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate chemical structure, C14H16N2O3S2, CAS 371202-49-2

Ethyl [(3-methyl-4-oxo-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate

CAS 371202-49-2C₁₄H₁₆N₂O₃S₂

2-((3-Allyl-4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N,N-bis(2-hydroxyethyl)acetamide chemical structure, C18H23N3O4S2, CAS 325693-30-9

2-((3-Allyl-4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N,N-bis(2-hydroxyethyl)acetamide

CAS 325693-30-9C₁₈H₂₃N₃O₄S₂