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Murcko scaffold

Ring system with 3 rings and 13 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
11
With full pages
6
Scaffold SMILES

O=C1c2ccccc2C2SCCN12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1c2ccccc2C2SCCN12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

5-Oxo-2,3,5,9b-tetrahydrothiazolo[2,3-a]isoindole-3-carboxylic acid chemical structure, C11H9NO3S, CAS 118726-68-4
5-Oxo-2,3,5,9b-tetrahydrothiazolo[2,3-a]isoindole-3-carboxylic acid
CAS 118726-68-4C11H9NO3S
2,2-Dimethyl-5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylic acid chemical structure, C13H13NO3S, CAS 1217983-08-8
2,2-Dimethyl-5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylic acid
CAS 1217983-08-8C13H13NO3S
Ethyl 9b-methyl-5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylate chemical structure, C14H15NO3S, CAS 1189773-98-5
Ethyl 9b-methyl-5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylate
CAS 1189773-98-5C14H15NO3S
(3R)-5-Oxo-3,9b-dihydro-2H-[1,3]thiazolo[2,3-a]isoindole-3-carboxylic acid chemical structure, C11H9NO3S, CAS 1212467-62-3
(3R)-5-Oxo-3,9b-dihydro-2H-[1,3]thiazolo[2,3-a]isoindole-3-carboxylic acid
CAS 1212467-62-3C11H9NO3S
Ethyl 5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylate chemical structure, C13H13NO3S, CAS 1100756-34-0
Ethyl 5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylate
CAS 1100756-34-0C13H13NO3S
6,7-Dimethoxy-2,2-dimethyl-5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylic acid chemical structure, C15H17NO5S, CAS 1219106-01-0
6,7-Dimethoxy-2,2-dimethyl-5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylic acid
CAS 1219106-01-0C15H17NO5S
2,2-Dimethyl-2,3-dihydro[1,3]thiazolo[2,3-a]isoindol-5(9bH)-one chemical structure, C12H13NOS, CAS 3063-82-9
2,2-Dimethyl-2,3-dihydro[1,3]thiazolo[2,3-a]isoindol-5(9bH)-one
CAS 3063-82-9C12H13NOS
2,2,9b-Trimethyl-2,3-dihydro[1,3]thiazolo[2,3-a]isoindol-5(9bH)-one chemical structure, C13H15NOS, CAS 439094-62-9
2,2,9b-Trimethyl-2,3-dihydro[1,3]thiazolo[2,3-a]isoindol-5(9bH)-one
CAS 439094-62-9C13H15NOS
6,7-Dimethoxy-5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylic acid chemical structure, C13H13NO5S, CAS 1170695-07-4
6,7-Dimethoxy-5-oxo-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxylic acid
CAS 1170695-07-4C13H13NO5S
(3R)-N-(3-Methoxypropyl)-2,2-dimethyl-5-oxo-3,9b-dihydro-[1,3]thiazolo[2,3-a]isoindole-3-carboxamide chemical structure, C17H22N2O3S, CAS 1214624-24-4
(3R)-N-(3-Methoxypropyl)-2,2-dimethyl-5-oxo-3,9b-dihydro-[1,3]thiazolo[2,3-a]isoindole-3-carboxamide
CAS 1214624-24-4C17H22N2O3S
(3R)-5-Oxo-N-pentyl-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxamide chemical structure, C16H20N2O2S, CAS 1173676-52-2
(3R)-5-Oxo-N-pentyl-2,3,5,9b-tetrahydro[1,3]thiazolo[2,3-a]isoindole-3-carboxamide
CAS 1173676-52-2C16H20N2O2S