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Murcko scaffold

Ring system with 3 rings and 13 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
27
With full pages
6
Scaffold SMILES

O=c1ccn2c(n1)OC1CCOC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn2c(n1)OC1CCOC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)- chemical structure, C9H10N2O5, CAS 2390200-32-3
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-
CAS 2390200-32-3C9H10N2O5
Adiaft chemical structure, C10H11IN2O4, CAS 142545-11-7
Adiaft
CAS 142545-11-7C10H11IN2O4
2,2'Anhydro-1-(beta-arabinofuranosyl)orotic acid hydrazide chemical structure, C10H12N4O6, CAS 76580-72-8
2,2'Anhydro-1-(beta-arabinofuranosyl)orotic acid hydrazide
CAS 76580-72-8C10H12N4O6
2,2'-Anhydro-1-beta-arabinofuranosylthymine chemical structure, C10H12N2O5, CAS 22423-26-3
2,2'-Anhydro-1-beta-arabinofuranosylthymine
CAS 22423-26-3C10H12N2O5
2,2'-Anhydro-1-(beta-D-arabinofuranosyl)orotic acid ethyl ester chemical structure, C12H14N2O7, CAS 33780-80-2
2,2'-Anhydro-1-(beta-D-arabinofuranosyl)orotic acid ethyl ester
CAS 33780-80-2C12H14N2O7
2,2'-Anhydro-1-(beta-arabinofuranosyl)-orotic acid chemical structure, C10H10N2O7, CAS 33886-20-3
2,2'-Anhydro-1-(beta-arabinofuranosyl)-orotic acid
CAS 33886-20-3C10H10N2O7
2,2'-Anhydro-3'-deoxy-5-ethyluridine chemical structure, C11H14N2O4, CAS 133177-88-5
2,2'-Anhydro-3'-deoxy-5-ethyluridine
CAS 133177-88-5C11H14N2O4
O2,2'-Anhydro-5-methyluridine chemical structure, C10H12N2O5, CAS 433733-92-7
O2,2'-Anhydro-5-methyluridine
CAS 433733-92-7C10H12N2O5
2,2'-Anhydrouridine chemical structure, C9H10N2O5, CAS 3736-77-4
2,2'-Anhydrouridine
CAS 3736-77-4C9H10N2O5
2,2'-Anhydro-L-thymidine chemical structure, C10H12N2O5
2,2'-Anhydro-L-thymidine
C10H12N2O5
5-(2-Bromovinyl)-2,2'-anhydrouridine chemical structure, C11H11BrN2O5, CAS 104988-76-3
5-(2-Bromovinyl)-2,2'-anhydrouridine
CAS 104988-76-3C11H11BrN2O5
((2R,3R,3aS,9aR)-3-Acetoxy-6-oxo-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-2-yl)methyl acetate chemical structure, C13H14N2O7, CAS 28309-53-7
((2R,3R,3aS,9aR)-3-Acetoxy-6-oxo-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-2-yl)methyl acetate
CAS 28309-53-7C13H14N2O7
2,2'-Anhydro-L-uridine chemical structure, C9H10N2O5, CAS 31501-46-9
2,2'-Anhydro-L-uridine
CAS 31501-46-9C9H10N2O5
(2R,4R,5R,6S)-5-Hydroxy-2,4-bis(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one chemical structure, C10H12N2O6
(2R,4R,5R,6S)-5-Hydroxy-2,4-bis(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one
C10H12N2O6
5-Ethyl-2,2'-anhydrouridine chemical structure, C11H14N2O5, CAS 72503-93-6
5-Ethyl-2,2'-anhydrouridine
CAS 72503-93-6C11H14N2O5
6H-Furo[2',3' chemical structure, C9H9N5O5, CAS 876707-99-2
6H-Furo[2',3'
CAS 876707-99-2C9H9N5O5
(2S,4S,5S,6S)-5-Hydroxy-4-(hydroxymethyl)-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one chemical structure, C10H12N2O5
(2S,4S,5S,6S)-5-Hydroxy-4-(hydroxymethyl)-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one
C10H12N2O5
2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil chemical structure, C11H12N2O7, CAS 36963-58-3
2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil
CAS 36963-58-3C11H12N2O7
(2R,3S,3aS,9aR)-2-(Difluoromethyl)-2,3,3a,9atetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one chemical structure, C10H10F2N2O5, CAS 1948282-17-4
(2R,3S,3aS,9aR)-2-(Difluoromethyl)-2,3,3a,9atetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one
CAS 1948282-17-4C10H10F2N2O5
(2R,3S,3aS,9aR)-2-(Fluoromethyl)-2,3,3a,9atetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one chemical structure, C10H11FN2O5, CAS 1948282-21-0
(2R,3S,3aS,9aR)-2-(Fluoromethyl)-2,3,3a,9atetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one
CAS 1948282-21-0C10H11FN2O5
(2S,3S,3AS,9AS)-3-Hydroxy-2-(hydroxymethyl)-3,3A-dihydro-2H-furo[2',3':4,5]oxazolo[3,2-A]pyrimidin-6(9AH)-one chemical structure, C9H10N2O5, CAS 2382469-62-5
(2S,3S,3AS,9AS)-3-Hydroxy-2-(hydroxymethyl)-3,3A-dihydro-2H-furo[2',3':4,5]oxazolo[3,2-A]pyrimidin-6(9AH)-one
CAS 2382469-62-5C9H10N2O5
(2S,3S,3aR,9aS)-7-Methyl-3-((trimethylsilyl)oxy)-2-(((trimethylsilyl)oxy)methyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one chemical structure, C16H28N2O5Si2, CAS 610303-53-2
(2S,3S,3aR,9aS)-7-Methyl-3-((trimethylsilyl)oxy)-2-(((trimethylsilyl)oxy)methyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one
CAS 610303-53-2C16H28N2O5Si2
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one,2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-2-(trifluoromethyl)-,(2R,3S,3aS,9aR)- chemical structure, C10H9F3N2O5, CAS 2987910-16-5
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one,2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-2-(trifluoromethyl)-,(2R,3S,3aS,9aR)-
CAS 2987910-16-5C10H9F3N2O5
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one,7-fluoro-2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-2-(trifluoromethyl)-,(2R,3S,3aS,9aR)- chemical structure, C10H8F4N2O5, CAS 2987909-84-0
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one,7-fluoro-2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-2-(trifluoromethyl)-,(2R,3S,3aS,9aR)-
CAS 2987909-84-0C10H8F4N2O5