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Murcko scaffold

4-(Oxolan-3-yl)-1H-pyrazole scaffold

29 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
29
With full pages
4
Scaffold SMILES

c1n[nH]cc1C1CCOC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Oxolan-3-yl)-1H-pyrazole page
Murcko scaffold c1n[nH]cc1C1CCOC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

rac-(2R,3R)-3-(1-Methyl-1H-pyrazol-4-yl)oxolane-2-carboxylic acid hydrochloride chemical structure, C9H13ClN2O3, CAS 2307772-55-8
rac-(2R,3R)-3-(1-Methyl-1H-pyrazol-4-yl)oxolane-2-carboxylic acid hydrochloride
CAS 2307772-55-8C9H13ClN2O3
3,5-Dimethyl-4-(oxolan-3-yl)-1H-pyrazole chemical structure, C9H14N2O, CAS 2097866-33-4
3,5-Dimethyl-4-(oxolan-3-yl)-1H-pyrazole
CAS 2097866-33-4C9H14N2O
4-(Oxolan-3-yl)-1H-pyrazole chemical structure, C7H10N2O, CAS 2097937-75-0
4-(Oxolan-3-yl)-1H-pyrazole
CAS 2097937-75-0C7H10N2O
rac-(2R,3R)-3-(1-Methyl-1H-pyrazol-4-yl)oxolane-2-carboxylic acid hydrochloride, cis chemical structure, C9H13ClN2O3, CAS 1989637-96-8
rac-(2R,3R)-3-(1-Methyl-1H-pyrazol-4-yl)oxolane-2-carboxylic acid hydrochloride, cis
CAS 1989637-96-8C9H13ClN2O3
2-[4-(Oxolan-3-yl)-1H-pyrazol-1-yl]acetic acid chemical structure, C9H12N2O3, CAS 2225136-79-6
2-[4-(Oxolan-3-yl)-1H-pyrazol-1-yl]acetic acid
CAS 2225136-79-6C9H12N2O3
2-[4-(Oxolan-3-yl)-1H-pyrazol-1-yl]ethan-1-amine chemical structure, C9H15N3O, CAS 2225137-20-0
2-[4-(Oxolan-3-yl)-1H-pyrazol-1-yl]ethan-1-amine
CAS 2225137-20-0C9H15N3O
N-{2-[4-(Oxolan-3-yl)-1H-pyrazol-1-yl]ethyl}prop-2-enamide chemical structure, C12H17N3O2, CAS 2361640-32-4
N-{2-[4-(Oxolan-3-yl)-1H-pyrazol-1-yl]ethyl}prop-2-enamide
CAS 2361640-32-4C12H17N3O2
(E)-4-(Dimethylamino)-N-[2-[4-(oxolan-3-yl)pyrazol-1-yl]ethyl]but-2-enamide chemical structure, C15H24N4O2, CAS 2411326-79-7
(E)-4-(Dimethylamino)-N-[2-[4-(oxolan-3-yl)pyrazol-1-yl]ethyl]but-2-enamide
CAS 2411326-79-7C15H24N4O2
N-[2-[4-(Oxolan-3-yl)pyrazol-1-yl]ethyl]but-2-ynamide chemical structure, C13H17N3O2, CAS 2411300-08-6
N-[2-[4-(Oxolan-3-yl)pyrazol-1-yl]ethyl]but-2-ynamide
CAS 2411300-08-6C13H17N3O2
2-Chloro-N-[2-[4-(oxolan-3-yl)pyrazol-1-yl]ethyl]acetamide chemical structure, C11H16ClN3O2, CAS 2411257-72-0
2-Chloro-N-[2-[4-(oxolan-3-yl)pyrazol-1-yl]ethyl]acetamide
CAS 2411257-72-0C11H16ClN3O2
3-(1-Methyl-1H-pyrazol-4-yl)oxolane-2-carboxylic acid hydrochloride chemical structure, C9H13ClN2O3, CAS 2138167-10-7
3-(1-Methyl-1H-pyrazol-4-yl)oxolane-2-carboxylic acid hydrochloride
CAS 2138167-10-7C9H13ClN2O3
Methyl 5-amino-1-tert-butyl-4-(oxolan-3-yl)-1H-pyrazole-3-carboxylate chemical structure, C13H21N3O3, CAS 2138358-85-5
Methyl 5-amino-1-tert-butyl-4-(oxolan-3-yl)-1H-pyrazole-3-carboxylate
CAS 2138358-85-5C13H21N3O3
Methyl 5-amino-1-methyl-4-(oxolan-3-yl)-1H-pyrazole-3-carboxylate chemical structure, C10H15N3O3, CAS 2137810-89-8
Methyl 5-amino-1-methyl-4-(oxolan-3-yl)-1H-pyrazole-3-carboxylate
CAS 2137810-89-8C10H15N3O3
Methyl 5-amino-4-(oxolan-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole-3-carboxylate chemical structure, C11H14F3N3O3, CAS 2137550-14-0
Methyl 5-amino-4-(oxolan-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole-3-carboxylate
CAS 2137550-14-0C11H14F3N3O3
rac-(3R,4S)-4-(1,3-Dimethyl-1H-pyrazol-4-yl)oxolan-3-ol chemical structure, C9H14N2O2, CAS 2227669-94-3
rac-(3R,4S)-4-(1,3-Dimethyl-1H-pyrazol-4-yl)oxolan-3-ol
CAS 2227669-94-3C9H14N2O2
4-(1,3-Dimethyl-1H-pyrazol-4-yl)oxolan-3-ol chemical structure, C9H14N2O2, CAS 2002831-03-8
4-(1,3-Dimethyl-1H-pyrazol-4-yl)oxolan-3-ol
CAS 2002831-03-8C9H14N2O2
4-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolan-3-ol chemical structure, C9H14N2O2, CAS 2172575-30-1
4-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolan-3-ol
CAS 2172575-30-1C9H14N2O2
rac-(3R,4S)-4-(1-Ethyl-1H-pyrazol-4-yl)oxolan-3-ol chemical structure, C9H14N2O2, CAS 2227806-06-4
rac-(3R,4S)-4-(1-Ethyl-1H-pyrazol-4-yl)oxolan-3-ol
CAS 2227806-06-4C9H14N2O2
rac-(3R,4S)-4-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolan-3-ol chemical structure, C9H14N2O2, CAS 2227738-93-2
rac-(3R,4S)-4-(1,5-Dimethyl-1H-pyrazol-4-yl)oxolan-3-ol
CAS 2227738-93-2C9H14N2O2
Methyl 5-amino-1-butyl-4-(oxolan-3-yl)-1H-pyrazole-3-carboxylate chemical structure, C13H21N3O3, CAS 2137622-36-5
Methyl 5-amino-1-butyl-4-(oxolan-3-yl)-1H-pyrazole-3-carboxylate
CAS 2137622-36-5C13H21N3O3
4-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-ol chemical structure, C8H12N2O2, CAS 2024868-69-5
4-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-ol
CAS 2024868-69-5C8H12N2O2
tert-Butyl N-[3-(1H-pyrazol-4-yl)oxolan-3-yl]carbamate chemical structure, C12H19N3O3, CAS 2228351-25-3
tert-Butyl N-[3-(1H-pyrazol-4-yl)oxolan-3-yl]carbamate
CAS 2228351-25-3C12H19N3O3
rac-(3R,4S)-4-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-ol chemical structure, C8H12N2O2, CAS 2227693-47-0
rac-(3R,4S)-4-(1-Methyl-1H-pyrazol-4-yl)oxolan-3-ol
CAS 2227693-47-0C8H12N2O2
4-(1-Ethyl-1H-pyrazol-4-yl)oxolan-3-ol chemical structure, C9H14N2O2, CAS 2023273-31-4
4-(1-Ethyl-1H-pyrazol-4-yl)oxolan-3-ol
CAS 2023273-31-4C9H14N2O2