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Murcko scaffold

1-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-3-phenylurea scaffold

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)Nc1cccc(-c2cn3cccnc3n2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-3-phenylurea page
Murcko scaffold O=C(Nc1ccccc1)Nc1cccc(-c2cn3cccnc3n2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-(2-Fluorophenyl)-N'-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)urea chemical structure, C19H14FN5O, CAS 861210-37-9
N-(2-Fluorophenyl)-N'-(3-imidazo[1,2-a]pyrimidin-2-ylphenyl)urea
CAS 861210-37-9C19H14FN5O
1-(4-Chlorophenyl)-3-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)urea chemical structure, C19H14ClN5O, CAS 862811-90-3
1-(4-Chlorophenyl)-3-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)urea
CAS 862811-90-3C19H14ClN5O
1-(5-(Imidazo[1,2-a]pyrimidin-2-yl)-2-methylphenyl)-3-phenylurea chemical structure, C20H17N5O, CAS 862811-91-4
1-(5-(Imidazo[1,2-a]pyrimidin-2-yl)-2-methylphenyl)-3-phenylurea
CAS 862811-91-4C20H17N5O
1-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-3-phenylurea chemical structure, C19H15N5O, CAS 862811-88-9
1-(3-Imidazo[1,2-a]pyrimidin-2-ylphenyl)-3-phenylurea
CAS 862811-88-9C19H15N5O
1-(3-Chlorophenyl)-3-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)urea chemical structure, C19H14ClN5O, CAS 862811-89-0
1-(3-Chlorophenyl)-3-(3-{imidazo[1,2-a]pyrimidin-2-yl}phenyl)urea
CAS 862811-89-0C19H14ClN5O
1-(3-Chlorophenyl)-3-(5-(imidazo[1,2-a]pyrimidin-2-yl)-2-methylphenyl)urea chemical structure, C20H16ClN5O, CAS 862811-92-5
1-(3-Chlorophenyl)-3-(5-(imidazo[1,2-a]pyrimidin-2-yl)-2-methylphenyl)urea
CAS 862811-92-5C20H16ClN5O
1-(4-Chlorophenyl)-3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methylphenyl)urea chemical structure, C20H16ClN5O, CAS 862811-93-6
1-(4-Chlorophenyl)-3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methylphenyl)urea
CAS 862811-93-6C20H16ClN5O
1-(5-(Imidazo[1,2-a]pyrimidin-2-yl)-2-methoxyphenyl)-3-phenylurea chemical structure, C20H17N5O2, CAS 862811-94-7
1-(5-(Imidazo[1,2-a]pyrimidin-2-yl)-2-methoxyphenyl)-3-phenylurea
CAS 862811-94-7C20H17N5O2
1-(3-Chlorophenyl)-3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)urea chemical structure, C20H16ClN5O2, CAS 862811-95-8
1-(3-Chlorophenyl)-3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)urea
CAS 862811-95-8C20H16ClN5O2
1-(4-Chlorophenyl)-3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)urea chemical structure, C20H16ClN5O2, CAS 862811-96-9
1-(4-Chlorophenyl)-3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)urea
CAS 862811-96-9C20H16ClN5O2
1-(3-(3-Methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)-3-phenylurea chemical structure, C20H17N5O, CAS 862812-00-8
1-(3-(3-Methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)-3-phenylurea
CAS 862812-00-8C20H17N5O
1-(3-Chlorophenyl)-3-(3-{3-methylimidazo[1,2-a]pyrimidin-2-yl}phenyl)urea chemical structure, C20H16ClN5O, CAS 862812-01-9
1-(3-Chlorophenyl)-3-(3-{3-methylimidazo[1,2-a]pyrimidin-2-yl}phenyl)urea
CAS 862812-01-9C20H16ClN5O
1-(4-Chlorophenyl)-3-(3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)urea chemical structure, C20H16ClN5O, CAS 862812-02-0
1-(4-Chlorophenyl)-3-(3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)urea
CAS 862812-02-0C20H16ClN5O
1-(3-(Difluoromethoxy)phenyl)-3-(3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)urea chemical structure, C21H17F2N5O2, CAS 2328417-00-9
1-(3-(Difluoromethoxy)phenyl)-3-(3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl)urea
CAS 2328417-00-9C21H17F2N5O2