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Murcko scaffold

N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-phenylacetamide scaffold

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
10
With full pages
1
Scaffold SMILES

O=C(Cc1ccccc1)Nc1cccc(-c2nc3ccccc3[nH]2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-phenylacetamide page
Murcko scaffold O=C(Cc1ccccc1)Nc1cccc(-c2nc3ccccc3[nH]2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-phenylacetamide chemical structure, C21H17N3O, CAS 331972-70-4
N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-phenylacetamide
CAS 331972-70-4C21H17N3O
N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-(3,4-dimethoxyphenyl)acetamide chemical structure, C23H21N3O3, CAS 500262-44-2
N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-(3,4-dimethoxyphenyl)acetamide
CAS 500262-44-2C23H21N3O3
N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-(4-methoxyphenyl)acetamide chemical structure, C22H19N3O2, CAS 364608-95-7
N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-(4-methoxyphenyl)acetamide
CAS 364608-95-7C22H19N3O2
N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-(4-bromophenyl)acetamide chemical structure, C21H16BrN3O, CAS 897791-34-3
N-[3-(1H-Benzimidazol-2-yl)phenyl]-2-(4-bromophenyl)acetamide
CAS 897791-34-3C21H16BrN3O
N-[3-(1H-Benzimidazol-2-yl)-2-methylphenyl]-2-phenylacetamide chemical structure, C22H19N3O, CAS 428847-80-7
N-[3-(1H-Benzimidazol-2-yl)-2-methylphenyl]-2-phenylacetamide
CAS 428847-80-7C22H19N3O
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-2-(4-fluorophenyl)acetamide chemical structure, C21H16FN3O, CAS 899958-52-2
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-2-(4-fluorophenyl)acetamide
CAS 899958-52-2C21H16FN3O
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-2-(4-(methylthio)phenyl)acetamide chemical structure, C22H19N3OS, CAS 941930-18-3
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-2-(4-(methylthio)phenyl)acetamide
CAS 941930-18-3C22H19N3OS
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-2-(4-(methylsulfonyl)phenyl)acetamide chemical structure, C22H19N3O3S, CAS 941930-79-6
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-2-(4-(methylsulfonyl)phenyl)acetamide
CAS 941930-79-6C22H19N3O3S
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-2-(4-(ethylsulfonyl)phenyl)acetamide chemical structure, C23H21N3O3S, CAS 941972-25-4
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-2-(4-(ethylsulfonyl)phenyl)acetamide
CAS 941972-25-4C23H21N3O3S
Benzoic acid, 3-(1H-benzimidazol-2-yl)-5-[[2-(4-methylphenyl)acetyl]amino]-, methyl ester chemical structure, C24H21N3O3, CAS 3074811-93-8
Benzoic acid, 3-(1H-benzimidazol-2-yl)-5-[[2-(4-methylphenyl)acetyl]amino]-, methyl ester
CAS 3074811-93-8C24H21N3O3