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Murcko scaffold

Ring system with 4 rings and 25 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
10
With full pages
1
Scaffold SMILES

O=C(Cc1ccccc1)Nc1cccc(-c2nc3ccccc3s2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)Nc1cccc(-c2nc3ccccc3s2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[5-(1,3-Benzothiazol-2-yl)-2-methoxyphenyl]-2-(4-chlorophenyl)acetamide chemical structure, C22H17ClN2O2S, CAS 838843-36-0
N-[5-(1,3-Benzothiazol-2-yl)-2-methoxyphenyl]-2-(4-chlorophenyl)acetamide
CAS 838843-36-0C22H17ClN2O2S
N-[3-(1,3-Benzothiazol-2-yl)-4-hydroxyphenyl]-2-phenylacetamide chemical structure, C21H16N2O2S, CAS 2533-13-3
N-[3-(1,3-Benzothiazol-2-yl)-4-hydroxyphenyl]-2-phenylacetamide
CAS 2533-13-3C21H16N2O2S
N-[3-(1,3-Benzothiazol-2-yl)phenyl]-2-(4-chlorophenyl)acetamide chemical structure, C21H15ClN2OS, CAS 6263-45-2
N-[3-(1,3-Benzothiazol-2-yl)phenyl]-2-(4-chlorophenyl)acetamide
CAS 6263-45-2C21H15ClN2OS
N-(3-(Benzo[d]thiazol-2-yl)phenyl)-2-(4-fluorophenyl)acetamide chemical structure, C21H15FN2OS, CAS 922700-61-6
N-(3-(Benzo[d]thiazol-2-yl)phenyl)-2-(4-fluorophenyl)acetamide
CAS 922700-61-6C21H15FN2OS
N-(3-(Benzo[d]thiazol-2-yl)phenyl)-2-(4-(ethylsulfonyl)phenyl)acetamide chemical structure, C23H20N2O3S2, CAS 941972-21-0
N-(3-(Benzo[d]thiazol-2-yl)phenyl)-2-(4-(ethylsulfonyl)phenyl)acetamide
CAS 941972-21-0C23H20N2O3S2
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(4-(methylthio)phenyl)acetamide chemical structure, C22H18N2O2S2, CAS 941930-10-5
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(4-(methylthio)phenyl)acetamide
CAS 941930-10-5C22H18N2O2S2
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(4-(methylsulfonyl)phenyl)acetamide chemical structure, C22H18N2O4S2, CAS 941971-45-5
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(4-(methylsulfonyl)phenyl)acetamide
CAS 941971-45-5C22H18N2O4S2
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(4-(ethylsulfonyl)phenyl)acetamide chemical structure, C23H20N2O4S2, CAS 942009-17-8
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(4-(ethylsulfonyl)phenyl)acetamide
CAS 942009-17-8C23H20N2O4S2
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(4-fluorophenyl)acetamide chemical structure, C21H15FN2O2S, CAS 922576-49-6
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(4-fluorophenyl)acetamide
CAS 922576-49-6C21H15FN2O2S
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(p-tolyl)acetamide chemical structure, C22H18N2O2S, CAS 923378-87-4
N-(3-(Benzo[d]thiazol-2-yl)-4-hydroxyphenyl)-2-(p-tolyl)acetamide
CAS 923378-87-4C22H18N2O2S