CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 27 atoms

69 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
69
With full pages
13
Scaffold SMILES

N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 69 of 69 chemicals

1-Allyl-N~3~-(3,4-dimethoxyphenethyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C26H27N5O4, CAS 845636-45-5
1-Allyl-N~3~-(3,4-dimethoxyphenethyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 845636-45-5C26H27N5O4
7-Ethyl-6-imino-N-[2-(4-methoxyphenyl)ethyl]-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C24H25N5O3, CAS 845809-53-2
7-Ethyl-6-imino-N-[2-(4-methoxyphenyl)ethyl]-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide
CAS 845809-53-2C24H25N5O3
2-Imino-N~3~-(4-methoxyphenethyl)-10-methyl-5-oxo-1-propyl-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C25H27N5O3, CAS 847376-85-6
2-Imino-N~3~-(4-methoxyphenethyl)-10-methyl-5-oxo-1-propyl-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 847376-85-6C25H27N5O3
1-(3-Ethoxypropyl)-2-imino-N~3~-(4-methoxyphenethyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C27H31N5O4, CAS 847045-15-2
1-(3-Ethoxypropyl)-2-imino-N~3~-(4-methoxyphenethyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 847045-15-2C27H31N5O4
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-1-(2-methoxyethyl)-10-methyl-5-oxodipyrido[3,4-c:1',2'-f]pyrimidine-3-carboxamide chemical structure, C26H29N5O5, CAS 846587-65-3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-1-(2-methoxyethyl)-10-methyl-5-oxodipyrido[3,4-c:1',2'-f]pyrimidine-3-carboxamide
CAS 846587-65-3C26H29N5O5
1-Butyl-2-imino-N-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C26H29N5O3, CAS 847917-11-7
1-Butyl-2-imino-N-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 847917-11-7C26H29N5O3
1-(3-Ethoxypropyl)-2-imino-N~3~-(4-methoxyphenethyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C26H29N5O4, CAS 848212-53-3
1-(3-Ethoxypropyl)-2-imino-N~3~-(4-methoxyphenethyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 848212-53-3C26H29N5O4
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(3-ethoxypropyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C27H31N5O5, CAS 844459-50-3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(3-ethoxypropyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 844459-50-3C27H31N5O5
N-[2-(3,4-Dimethoxyphenyl)ethyl]-6-imino-11-methyl-2-oxo-7-propyl-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C26H29N5O4, CAS 847270-33-1
N-[2-(3,4-Dimethoxyphenyl)ethyl]-6-imino-11-methyl-2-oxo-7-propyl-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide
CAS 847270-33-1C26H29N5O4
2-Imino-1-(3-isopropoxypropyl)-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C27H31N5O3, CAS 844451-21-4
2-Imino-1-(3-isopropoxypropyl)-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 844451-21-4C27H31N5O3
2-Imino-N~3~-(4-methoxyphenethyl)-10-methyl-5-oxo-1-pentyl-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C27H31N5O3, CAS 849917-21-1
2-Imino-N~3~-(4-methoxyphenethyl)-10-methyl-5-oxo-1-pentyl-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 849917-21-1C27H31N5O3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-7-ethyl-6-imino-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C24H25N5O4, CAS 573695-30-4
N-[2-(3,4-Dimethoxyphenyl)ethyl]-7-ethyl-6-imino-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide
CAS 573695-30-4C24H25N5O4
1-(3-Ethoxypropyl)-2-imino-10-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C26H29N5O3, CAS 879856-19-6
1-(3-Ethoxypropyl)-2-imino-10-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 879856-19-6C26H29N5O3
1-Butyl-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C27H31N5O4, CAS 848058-35-5
1-Butyl-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 848058-35-5C27H31N5O4
2-Imino-1-isopropyl-N~3~-(4-methoxyphenethyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide chemical structure, C25H27N5O3, CAS 893703-62-3
2-Imino-1-isopropyl-N~3~-(4-methoxyphenethyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide
CAS 893703-62-3C25H27N5O3
2-Imino-N-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1-[3-(propan-2-yloxy)propyl]-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C28H33N5O4, CAS 893703-59-8
2-Imino-N-[2-(4-methoxyphenyl)ethyl]-10-methyl-5-oxo-1-[3-(propan-2-yloxy)propyl]-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 893703-59-8C28H33N5O4
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(3-ethoxypropyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C28H33N5O5, CAS 846581-21-3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(3-ethoxypropyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 846581-21-3C28H33N5O5
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-1-(3-methoxypropyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C27H31N5O5, CAS 845632-11-3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2-imino-1-(3-methoxypropyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 845632-11-3C27H31N5O5
1-Ethyl-2-imino-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C23H23N5O2, CAS 865551-63-9
1-Ethyl-2-imino-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 865551-63-9C23H23N5O2
1-(3-Ethoxypropyl)-2-imino-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C26H29N5O3, CAS 879954-38-8
1-(3-Ethoxypropyl)-2-imino-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 879954-38-8C26H29N5O3
1-(Butan-2-yl)-2-imino-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide chemical structure, C25H27N5O2, CAS 880394-46-7
1-(Butan-2-yl)-2-imino-8-methyl-5-oxo-N-(2-phenylethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
CAS 880394-46-7C25H27N5O2