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Murcko scaffold

Ring system with 2 rings and 19 atoms

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
18
With full pages
8
Scaffold SMILES

C=C(C(=O)c1ccccc1)S(=O)(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C(C(=O)c1ccccc1)S(=O)(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-(4-Chlorophenyl)-2-[(4-chlorophenyl)sulfonyl]-3-(dimethylamino)-2-propen-1-one chemical structure, C17H15Cl2NO3S, CAS 1164563-97-6
1-(4-Chlorophenyl)-2-[(4-chlorophenyl)sulfonyl]-3-(dimethylamino)-2-propen-1-one
CAS 1164563-97-6C17H15Cl2NO3S
1-(4-Chlorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one chemical structure, C17H16ClNO3S, CAS 1164473-32-8
1-(4-Chlorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one
CAS 1164473-32-8C17H16ClNO3S
1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-[(4-fluorophenyl)sulfonyl]-2-propen-1-one chemical structure, C17H14Cl2FNO3S, CAS 344265-59-4
1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-[(4-fluorophenyl)sulfonyl]-2-propen-1-one
CAS 344265-59-4C17H14Cl2FNO3S
3-(Dimethylamino)-1-(4-methoxyphenyl)-2-(phenylsulfonyl)-2-propen-1-one chemical structure, C18H19NO4S, CAS 344266-67-7
3-(Dimethylamino)-1-(4-methoxyphenyl)-2-(phenylsulfonyl)-2-propen-1-one
CAS 344266-67-7C18H19NO4S
3-(Dimethylamino)-1-(4-fluorophenyl)-2-(phenylsulfonyl)-2-propen-1-one chemical structure, C17H16FNO3S, CAS 344266-75-7
3-(Dimethylamino)-1-(4-fluorophenyl)-2-(phenylsulfonyl)-2-propen-1-one
CAS 344266-75-7C17H16FNO3S
3-(Dimethylamino)-1-(4-fluorophenyl)-2-[(4-fluorophenyl)sulfonyl]-2-propen-1-one chemical structure, C17H15F2NO3S, CAS 344266-90-6
3-(Dimethylamino)-1-(4-fluorophenyl)-2-[(4-fluorophenyl)sulfonyl]-2-propen-1-one
CAS 344266-90-6C17H15F2NO3S
1-(3,4-Dichlorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one chemical structure, C17H15Cl2NO3S, CAS 344266-98-4
1-(3,4-Dichlorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one
CAS 344266-98-4C17H15Cl2NO3S
1-(2-Chlorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one chemical structure, C17H16ClNO3S, CAS 344267-05-6
1-(2-Chlorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one
CAS 344267-05-6C17H16ClNO3S
1-(2-Chloro-4,5-difluorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one chemical structure, C17H14ClF2NO3S, CAS 400088-09-7
1-(2-Chloro-4,5-difluorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one
CAS 400088-09-7C17H14ClF2NO3S
1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one chemical structure, C17H15Cl2NO3S, CAS 1164528-38-4
1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-(phenylsulfonyl)-2-propen-1-one
CAS 1164528-38-4C17H15Cl2NO3S
2-[(4-Chlorophenyl)sulfonyl]-3-(dimethylamino)-1-phenyl-2-propen-1-one chemical structure, C17H16ClNO3S, CAS 339108-26-8
2-[(4-Chlorophenyl)sulfonyl]-3-(dimethylamino)-1-phenyl-2-propen-1-one
CAS 339108-26-8C17H16ClNO3S
2-[(4-Chlorophenyl)sulfonyl]-1-(2,4-dichlorophenyl)-3-(dimethylamino)-2-propen-1-one chemical structure, C17H14Cl3NO3S, CAS 1164515-74-5
2-[(4-Chlorophenyl)sulfonyl]-1-(2,4-dichlorophenyl)-3-(dimethylamino)-2-propen-1-one
CAS 1164515-74-5C17H14Cl3NO3S
2-Propen-1-one, 3-ethoxy-1-phenyl-2-(phenylsulfonyl)- chemical structure, C17H16O4S, CAS 32083-40-2
2-Propen-1-one, 3-ethoxy-1-phenyl-2-(phenylsulfonyl)-
CAS 32083-40-2C17H16O4S
1-(4-Chlorophenyl)-3-(dimethylamino)-2-[(4-methylphenyl)sulfonyl]-2-propen-1-one chemical structure, C18H18ClNO3S, CAS 338417-78-0
1-(4-Chlorophenyl)-3-(dimethylamino)-2-[(4-methylphenyl)sulfonyl]-2-propen-1-one
CAS 338417-78-0C18H18ClNO3S
3-(Dimethylamino)-1-phenyl-2-(phenylsulfonyl)-2-propen-1-one chemical structure, C17H17NO3S, CAS 108289-88-9
3-(Dimethylamino)-1-phenyl-2-(phenylsulfonyl)-2-propen-1-one
CAS 108289-88-9C17H17NO3S
(2Z)-2-[(2,5-Difluorophenyl)sulfonyl]-3-(dimethylamino)-1-phenylprop-2-en-1-one chemical structure, C17H15F2NO3S, CAS 1325549-86-7
(2Z)-2-[(2,5-Difluorophenyl)sulfonyl]-3-(dimethylamino)-1-phenylprop-2-en-1-one
CAS 1325549-86-7C17H15F2NO3S
3-Ethoxy-2-(4-methylbenzene-1-sulfonyl)-1-phenylprop-2-en-1-one chemical structure, C18H18O4S, CAS 64326-20-1
3-Ethoxy-2-(4-methylbenzene-1-sulfonyl)-1-phenylprop-2-en-1-one
CAS 64326-20-1C18H18O4S
(2Z)-3-Ethoxy-2-[(2-nitrophenyl)sulfonyl]-1-phenylprop-2-en-1-one chemical structure, C17H15NO6S, CAS 1785910-25-9
(2Z)-3-Ethoxy-2-[(2-nitrophenyl)sulfonyl]-1-phenylprop-2-en-1-one
CAS 1785910-25-9C17H15NO6S