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Murcko scaffold

Ring system with 2 rings and 17 atoms

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
19
With full pages
9
Scaffold SMILES

O=C(C=Cc1ccccc1)c1cccoc1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)c1cccoc1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

4-Hydroxy-6-methyl-3-[(2E)-3-phenylprop-2-enoyl]-2H-pyran-2-one chemical structure, C15H12O4, CAS 593278-92-3
4-Hydroxy-6-methyl-3-[(2E)-3-phenylprop-2-enoyl]-2H-pyran-2-one
CAS 593278-92-3C15H12O4
4-Hydroxy-3-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-methyl-2H-pyran-2-one chemical structure, C15H12O5, CAS 14006-18-9
4-Hydroxy-3-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-methyl-2H-pyran-2-one
CAS 14006-18-9C15H12O5
(E)-4-Hydroxy-3-(3-(2-hydroxyphenyl)acryloyl)-6-methyl-2H-pyran-2-one chemical structure, C15H12O5, CAS 14073-10-0
(E)-4-Hydroxy-3-(3-(2-hydroxyphenyl)acryloyl)-6-methyl-2H-pyran-2-one
CAS 14073-10-0C15H12O5
(E)-4-Hydroxy-3-(3-(4-hydroxy-3-methoxyphenyl)acryloyl)-6-methyl-2H-pyran-2-one chemical structure, C16H14O6, CAS 851517-09-4
(E)-4-Hydroxy-3-(3-(4-hydroxy-3-methoxyphenyl)acryloyl)-6-methyl-2H-pyran-2-one
CAS 851517-09-4C16H14O6
Suptopin-2 chemical structure, C17H16O7, CAS 331852-66-5
Suptopin-2
CAS 331852-66-5C17H16O7
4-Hydroxy-3-[3-(2-hydroxy-3-methoxyphenyl)acryloyl]-6-methyl-2H-pyran-2-one chemical structure, C16H14O6, CAS 1164552-03-7
4-Hydroxy-3-[3-(2-hydroxy-3-methoxyphenyl)acryloyl]-6-methyl-2H-pyran-2-one
CAS 1164552-03-7C16H14O6
4-Hydroxy-6-methyl-3-[(E)-3-(3-nitro-phenyl)-acryloyl]-pyran-2-one chemical structure, C15H11NO6, CAS 14073-09-7
4-Hydroxy-6-methyl-3-[(E)-3-(3-nitro-phenyl)-acryloyl]-pyran-2-one
CAS 14073-09-7C15H11NO6
3-Cinnamoyl-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C15H12O4, CAS 56364-25-1
3-Cinnamoyl-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 56364-25-1C15H12O4
3-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C17H16O6, CAS 49821-34-3
3-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 49821-34-3C17H16O6
3-[(2E)-3-(4-Chlorophenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C15H11ClO4, CAS 14073-08-6
3-[(2E)-3-(4-Chlorophenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 14073-08-6C15H11ClO4
4-Hydroxy-3-(4-hydroxy-3-nitrocinnamoyl)-6-methyl-2H-pyran-2-one chemical structure, C15H11NO7, CAS 851517-08-3
4-Hydroxy-3-(4-hydroxy-3-nitrocinnamoyl)-6-methyl-2H-pyran-2-one
CAS 851517-08-3C15H11NO7
4-Hydroxy-6-methyl-3-[3-(4-methylphenyl)acryloyl]-2H-pyran-2-one chemical structure, C16H14O4, CAS 1236280-71-9
4-Hydroxy-6-methyl-3-[3-(4-methylphenyl)acryloyl]-2H-pyran-2-one
CAS 1236280-71-9C16H14O4
(E)-3-(3-(4-(Dimethylamino)phenyl)acryloyl)-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C17H17NO4, CAS 14073-11-1
(E)-3-(3-(4-(Dimethylamino)phenyl)acryloyl)-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 14073-11-1C17H17NO4
4-Hydroxy-3-[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]-6-methyl-2H-pyran-2-one chemical structure, C16H14O5, CAS 593278-93-4
4-Hydroxy-3-[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]-6-methyl-2H-pyran-2-one
CAS 593278-93-4C16H14O5
3-[(2E)-3-(2,4-Dichlorophenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C15H10Cl2O4, CAS 1141393-10-3
3-[(2E)-3-(2,4-Dichlorophenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 1141393-10-3C15H10Cl2O4
3-[(2E)-3-(3,4-Dichlorophenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C15H10Cl2O4, CAS 1262618-28-9
3-[(2E)-3-(3,4-Dichlorophenyl)prop-2-enoyl]-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 1262618-28-9C15H10Cl2O4
(E)-3-(3-(4-Fluorophenyl)acryloyl)-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C15H11FO4, CAS 1006372-29-7
(E)-3-(3-(4-Fluorophenyl)acryloyl)-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 1006372-29-7C15H11FO4
(E)-4-Hydroxy-6-methyl-3-(3-(2,4,5-trimethoxyphenyl)acryloyl)-2H-pyran-2-one chemical structure, C18H18O7, CAS 412958-51-1
(E)-4-Hydroxy-6-methyl-3-(3-(2,4,5-trimethoxyphenyl)acryloyl)-2H-pyran-2-one
CAS 412958-51-1C18H18O7
3-[4-(Diethylamino)cinnamoyl]-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C19H21NO4, CAS 1141393-07-8
3-[4-(Diethylamino)cinnamoyl]-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 1141393-07-8C19H21NO4