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Murcko scaffold

1-Phenylimidazolidine-2,4-dione scaffold

58 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
58
With full pages
16
Scaffold SMILES

O=C1CN(c2ccccc2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenylimidazolidine-2,4-dione page
Murcko scaffold O=C1CN(c2ccccc2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 58 chemicals

1-(3-Chlorophenyl)-5-hydroxy-3-methylimidazolidine-2,4-dione chemical structure, C10H9ClN2O3, CAS 34065-97-9
1-(3-Chlorophenyl)-5-hydroxy-3-methylimidazolidine-2,4-dione
CAS 34065-97-9C10H9ClN2O3
Ethyl 1-methyl-2,5-dioxo-3-phenylimidazolidine-4-carboxylate chemical structure, C13H14N2O4, CAS 56598-96-0
Ethyl 1-methyl-2,5-dioxo-3-phenylimidazolidine-4-carboxylate
CAS 56598-96-0C13H14N2O4
5-Hydroxy-3-methyl-1-phenylimidazolidine-2,4-dione chemical structure, C10H10N2O3, CAS 32533-76-9
5-Hydroxy-3-methyl-1-phenylimidazolidine-2,4-dione
CAS 32533-76-9C10H10N2O3
1-Phenylimidazolidine-2,4-dione chemical structure, C9H8N2O2, CAS 15414-78-5
1-Phenylimidazolidine-2,4-dione
CAS 15414-78-5C9H8N2O2
1-(4-Hydroxyphenyl)imidazolidine-2,4-dione chemical structure, C9H8N2O3, CAS 26850-25-9
1-(4-Hydroxyphenyl)imidazolidine-2,4-dione
CAS 26850-25-9C9H8N2O3
1-P-Tolyl-imidazolidine-2,4-dione chemical structure, C10H10N2O2, CAS 32549-31-8
1-P-Tolyl-imidazolidine-2,4-dione
CAS 32549-31-8C10H10N2O2
2,4-Imidazolidinedione, 1-(3-methylphenyl)- chemical structure, C10H10N2O2, CAS 32549-32-9
2,4-Imidazolidinedione, 1-(3-methylphenyl)-
CAS 32549-32-9C10H10N2O2
1-(4-Chlorophenyl)imidazolidine-2,4-dione chemical structure, C9H7ClN2O2, CAS 32549-33-0
1-(4-Chlorophenyl)imidazolidine-2,4-dione
CAS 32549-33-0C9H7ClN2O2
1-(2-Methylphenyl)imidazolidine-2,4-dione chemical structure, C10H10N2O2, CAS 60984-45-4
1-(2-Methylphenyl)imidazolidine-2,4-dione
CAS 60984-45-4C10H10N2O2
1-(4-Methoxyphenyl)hydantoin chemical structure, C10H10N2O3, CAS 41526-30-1
1-(4-Methoxyphenyl)hydantoin
CAS 41526-30-1C10H10N2O3
1-(4-Bromophenyl)-2,4-imidazolidinedione chemical structure, C9H7BrN2O2, CAS 32549-34-1
1-(4-Bromophenyl)-2,4-imidazolidinedione
CAS 32549-34-1C9H7BrN2O2
5-Methyl-1-phenylimidazolidine-2,4-dione chemical structure, C10H10N2O2, CAS 105510-41-6
5-Methyl-1-phenylimidazolidine-2,4-dione
CAS 105510-41-6C10H10N2O2
1-(4-Ethoxyphenyl)imidazolidine-2,4-dione chemical structure, C11H12N2O3, CAS 392701-75-6
1-(4-Ethoxyphenyl)imidazolidine-2,4-dione
CAS 392701-75-6C11H12N2O3
5-Methyl-1-(4-methylphenyl)imidazolidine-2,4-dione chemical structure, C11H12N2O2, CAS 1008214-93-4
5-Methyl-1-(4-methylphenyl)imidazolidine-2,4-dione
CAS 1008214-93-4C11H12N2O2
2-(4-Methyl-2,5-dioxo-3-phenylimidazolidin-1-yl)ethanesulfonyl fluoride chemical structure, C12H13FN2O4S, CAS 202065-43-8
2-(4-Methyl-2,5-dioxo-3-phenylimidazolidin-1-yl)ethanesulfonyl fluoride
CAS 202065-43-8C12H13FN2O4S
1-(2-Ethylphenyl)imidazolidine-2,4-dione chemical structure, C11H12N2O2, CAS 755022-10-7
1-(2-Ethylphenyl)imidazolidine-2,4-dione
CAS 755022-10-7C11H12N2O2
1-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione chemical structure, C10H9FN2O2, CAS 1008930-80-0
1-(4-Fluorophenyl)-5-methylimidazolidine-2,4-dione
CAS 1008930-80-0C10H9FN2O2
1-(4-Chlorophenyl)-5-methylimidazolidine-2,4-dione chemical structure, C10H9ClN2O2, CAS 1008068-93-6
1-(4-Chlorophenyl)-5-methylimidazolidine-2,4-dione
CAS 1008068-93-6C10H9ClN2O2
2-(4-Methyl-3-(4-methylphenyl)-2,5-dioxoimidazolidin-1-yl)acetic acid chemical structure, C13H14N2O4, CAS 1008949-74-3
2-(4-Methyl-3-(4-methylphenyl)-2,5-dioxoimidazolidin-1-yl)acetic acid
CAS 1008949-74-3C13H14N2O4
3-Amino-1-(2-hydroxyphenyl)imidazolidine-2,4-dione chemical structure, C9H9N3O3, CAS 185418-05-7
3-Amino-1-(2-hydroxyphenyl)imidazolidine-2,4-dione
CAS 185418-05-7C9H9N3O3
3-Methyl-1-phenylimidazolidine-2,4-dione chemical structure, C10H10N2O2, CAS 55889-14-0
3-Methyl-1-phenylimidazolidine-2,4-dione
CAS 55889-14-0C10H10N2O2
Ethyl 1-ethyl-2,5-dioxo-3-phenylimidazolidine-4-carboxylate chemical structure, C14H16N2O4, CAS 88100-50-9
Ethyl 1-ethyl-2,5-dioxo-3-phenylimidazolidine-4-carboxylate
CAS 88100-50-9C14H16N2O4
1-Phenyl-3-(3-sulfanylpropyl)imidazolidine-2,4-dione chemical structure, C12H14N2O2S, CAS 112108-92-6
1-Phenyl-3-(3-sulfanylpropyl)imidazolidine-2,4-dione
CAS 112108-92-6C12H14N2O2S
1-(4-Fluorophenyl)-3-(3-sulfanylpropyl)imidazolidine-2,4-dione chemical structure, C12H13FN2O2S, CAS 112108-93-7
1-(4-Fluorophenyl)-3-(3-sulfanylpropyl)imidazolidine-2,4-dione
CAS 112108-93-7C12H13FN2O2S