Murcko scaffold
Ring system with 2 rings and 11 atoms
28 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 28
- With full pages
- 3
Scaffold SMILES
c1cncc(CC2CCC2)c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 28 of 28 chemicals
Cyclobutyl(pyridin-3-yl)methanamine
CAS 1337455-60-3C10H14N2
![1-[(6-Chloropyridin-3-yl)methyl]cyclobutane-1-carboxylic acid chemical structure, C11H12ClNO2, CAS 1556671-16-9](/s/OPRZSOGRGWFIPK-UHFFFAOYSA-N.svg)
1-[(6-Chloropyridin-3-yl)methyl]cyclobutane-1-carboxylic acid
CAS 1556671-16-9C11H12ClNO2
![3-[(Pyridin-3-yl)methyl]cyclobutane-1-carboxylic acid chemical structure, C11H13NO2, CAS 1514813-30-9](/s/YPVWIZVEUQDVOF-UHFFFAOYSA-N.svg)
3-[(Pyridin-3-yl)methyl]cyclobutane-1-carboxylic acid
CAS 1514813-30-9C11H13NO2
![1-[(Pyridin-3-yl)methyl]cyclobutan-1-amine chemical structure, C10H14N2, CAS 1507947-49-0](/s/VXXMQXFAWHGVLV-UHFFFAOYSA-N.svg)
1-[(Pyridin-3-yl)methyl]cyclobutan-1-amine
CAS 1507947-49-0C10H14N2
![[1-(Pyridin-3-ylmethyl)cyclobutyl]methanamine chemical structure, C11H16N2, CAS 1550824-35-5](/s/VGCNWQDNNABMLW-UHFFFAOYSA-N.svg)
[1-(Pyridin-3-ylmethyl)cyclobutyl]methanamine
CAS 1550824-35-5C11H16N2
Cyclobutyl(pyridin-3-yl)methanamine hydrochloride
CAS 1864052-44-7C10H15ClN2
(1R)-1-Cyclobutyl-1-(pyridin-3-yl)methanamine
CAS 1335461-14-7C10H14N2
![1-[(Pyridin-3-yl)methyl]cyclobutane-1-carbaldehyde chemical structure, C11H13NO, CAS 1936683-46-3](/s/QINNWQQZJKRIBT-UHFFFAOYSA-N.svg)
1-[(Pyridin-3-yl)methyl]cyclobutane-1-carbaldehyde
CAS 1936683-46-3C11H13NO
![1-[Amino(pyridin-3-yl)methyl]cyclobutan-1-ol chemical structure, C10H14N2O, CAS 1402152-62-8](/s/MICZFLMOJLLTPC-UHFFFAOYSA-N.svg)
1-[Amino(pyridin-3-yl)methyl]cyclobutan-1-ol
CAS 1402152-62-8C10H14N2O
1-(Pyridin-3-ylmethyl)cyclobutanecarboxylic acid hydrochloride
CAS 2197062-79-4C11H14ClNO2
(R)-Cyclobutyl(pyridin-3-yl)methanamine dihydrochloride
CAS 2248176-07-8C10H16Cl2N2
![1-[(6-Chloropyridin-3-yl)methyl]cyclobutan-1-amine hydrochloride chemical structure, C10H14Cl2N2, CAS 2472671-94-4](/s/PNGLPRMPGKYDKS-UHFFFAOYSA-N.svg)
1-[(6-Chloropyridin-3-yl)methyl]cyclobutan-1-amine hydrochloride
CAS 2472671-94-4C10H14Cl2N2
1-((6-Chloropyridin-3-yl)methyl)cyclobutan-1-amine
CAS 2358071-76-6C10H13ClN2
![1-[(6-Chloropyridin-3-yl)methyl]cyclobutan-1-amine dihydrochloride chemical structure, C10H15Cl3N2, CAS 2416234-78-9](/s/SJDUAVDYIZHJSO-UHFFFAOYSA-N.svg)
1-[(6-Chloropyridin-3-yl)methyl]cyclobutan-1-amine dihydrochloride
CAS 2416234-78-9C10H15Cl3N2
![Methyl 1-[(6-chloropyridin-3-yl)methyl]cyclobutane-1-carboxylate chemical structure, C12H14ClNO2, CAS 2418726-31-3](/s/RWNVQYMCXAFCNV-UHFFFAOYSA-N.svg)
Methyl 1-[(6-chloropyridin-3-yl)methyl]cyclobutane-1-carboxylate
CAS 2418726-31-3C12H14ClNO2
![tert-Butyl 1-[(6-chloropyridin-3-yl)methyl]cyclobutane-1-carboxylate chemical structure, C15H20ClNO2, CAS 2504203-03-4](/s/GXVXKUPNQYRYKN-UHFFFAOYSA-N.svg)
tert-Butyl 1-[(6-chloropyridin-3-yl)methyl]cyclobutane-1-carboxylate
CAS 2504203-03-4C15H20ClNO2
![tert-Butyl N-{1-[(6-chloropyridin-3-yl)methyl]cyclobutyl}carbamate chemical structure, C15H21ClN2O2, CAS 2504203-39-6](/s/FDMGABBPIANHBN-UHFFFAOYSA-N.svg)
tert-Butyl N-{1-[(6-chloropyridin-3-yl)methyl]cyclobutyl}carbamate
CAS 2504203-39-6C15H21ClN2O2
1-(3-Methoxycyclobutyl)-1-(pyridin-3-yl)methanamine
CAS 2162060-60-6C11H16N2O
![2-[(4-Aminopyridin-3-yl)methyl]cyclobutan-1-ol chemical structure, C10H14N2O, CAS 2172474-24-5](/s/PQTDJPPJRSJPLO-UHFFFAOYSA-N.svg)
2-[(4-Aminopyridin-3-yl)methyl]cyclobutan-1-ol
CAS 2172474-24-5C10H14N2O
![1-[Amino(pyridin-3-yl)methyl]-3,3-bis(fluoromethyl)cyclobutan-1-ol chemical structure, C12H16F2N2O, CAS 2172585-93-0](/s/HFMNPMYZWMKKFA-UHFFFAOYSA-N.svg)
1-[Amino(pyridin-3-yl)methyl]-3,3-bis(fluoromethyl)cyclobutan-1-ol
CAS 2172585-93-0C12H16F2N2O
![2-[(Pyridin-3-yl)methyl]cyclobutan-1-ol chemical structure, C10H13NO, CAS 2172525-83-4](/s/JFMCCTUEUXRYCB-UHFFFAOYSA-N.svg)
2-[(Pyridin-3-yl)methyl]cyclobutan-1-ol
CAS 2172525-83-4C10H13NO
![2-[(2-Aminopyridin-3-yl)methyl]cyclobutan-1-ol chemical structure, C10H14N2O, CAS 2172488-59-2](/s/OBIQDXIUGNKGRX-UHFFFAOYSA-N.svg)
2-[(2-Aminopyridin-3-yl)methyl]cyclobutan-1-ol
CAS 2172488-59-2C10H14N2O
![2-[(5-Chloropyridin-3-yl)methyl]cyclobutan-1-ol chemical structure, C10H12ClNO, CAS 2150073-90-6](/s/GXOVFZGQVKZRSA-UHFFFAOYSA-N.svg)
2-[(5-Chloropyridin-3-yl)methyl]cyclobutan-1-ol
CAS 2150073-90-6C10H12ClNO
![2-[(5-Bromopyridin-3-yl)methyl]cyclobutan-1-ol chemical structure, C10H12BrNO, CAS 2160601-90-9](/s/YTTDGMFSDKPJLF-UHFFFAOYSA-N.svg)
2-[(5-Bromopyridin-3-yl)methyl]cyclobutan-1-ol
CAS 2160601-90-9C10H12BrNO
- 1-[(6-Methoxypyridin-3-yl)methyl]cyclobutane-1-carboxylic acid hydrochloride2748241-50-9C12H16ClNO3
- 1-((6-Methoxypyridin-3-yl)methyl)cyclobutan-1-amine dihydrochloride2749755-86-8C11H18Cl2N2O
- 1-((6-(Dimethylamino)pyridin-3-yl)methyl)cyclobutane-1-carboxylic acid dihydrochloride2748614-91-5C13H20Cl2N2O2
- (1S)-1-Cyclobutyl-1-(pyridin-3-yl)methanamine dihydrochloride2994296-84-1C10H16Cl2N2
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CCC2)cc148 chemicals
c1ccc(CC2CNC2)cc141 chemicals
c1ccc(OC2CNC2)cc131 chemicals
c1ccc(CN2CCC2)cc115 chemicals
c1ccc(NC2COC2)cc114 chemicals
c1ccc(NC2CCC2)cc112 chemicals
c1ccc(OC2CCC2)cc112 chemicals
c1ccc(OC2COC2)cc110 chemicals
c1ccc(CC2COC2)cc18 chemicals
O=S(=O)(c1ccccc1)N1CCC18 chemicals
c1ccc(OC2CCC2)nc18 chemicals
C(=C1CNC1)c1ccccc16 chemicals