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Murcko scaffold

Ring system with 2 rings and 16 atoms

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
27
With full pages
3
Scaffold SMILES

O=C(C=Cc1ccncc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccncc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

1-(4-Methoxyphenyl)-3-(4-pyridyl)prop-2-en-1-one chemical structure, C15H13NO2, CAS 72512-24-4
1-(4-Methoxyphenyl)-3-(4-pyridyl)prop-2-en-1-one
CAS 72512-24-4C15H13NO2
(E)-1-(2-Hydroxy-4-methoxyphenyl)-3-pyridin-4-ylprop-2-en-1-one chemical structure, C15H13NO3, CAS 7401-39-0
(E)-1-(2-Hydroxy-4-methoxyphenyl)-3-pyridin-4-ylprop-2-en-1-one
CAS 7401-39-0C15H13NO3
(E)-1-(5-Chloro-2-hydroxyphenyl)-3-pyridin-4-ylprop-2-en-1-one chemical structure, C14H10ClNO2, CAS 2110-10-3
(E)-1-(5-Chloro-2-hydroxyphenyl)-3-pyridin-4-ylprop-2-en-1-one
CAS 2110-10-3C14H10ClNO2
1-Phenyl-3-(4-pyridinyl)-2-propen-1-one chemical structure, C14H11NO, CAS 16208-85-8
1-Phenyl-3-(4-pyridinyl)-2-propen-1-one
CAS 16208-85-8C14H11NO
1-(4-Methoxyphenyl)-3-(pyridin-4-yl)prop-2-en-1-one chemical structure, C15H13NO2, CAS 910222-65-0
1-(4-Methoxyphenyl)-3-(pyridin-4-yl)prop-2-en-1-one
CAS 910222-65-0C15H13NO2
Acrylophenone, 3'-amino-3-(4-pyridyl)- chemical structure, C14H12N2O, CAS 64908-87-8
Acrylophenone, 3'-amino-3-(4-pyridyl)-
CAS 64908-87-8C14H12N2O
2,4-Dimethoxy-5-[(E)-3-pyridin-4-ylprop-2-enoyl]benzoic acid chemical structure, C17H15NO5, CAS 62435-22-7
2,4-Dimethoxy-5-[(E)-3-pyridin-4-ylprop-2-enoyl]benzoic acid
CAS 62435-22-7C17H15NO5
Acrylophenone, 4'-amino-3-(4-pyridyl)- chemical structure, C14H12N2O, CAS 40665-25-6
Acrylophenone, 4'-amino-3-(4-pyridyl)-
CAS 40665-25-6C14H12N2O
Dilmefone chemical structure, C16H15NO3, CAS 37398-31-5
Dilmefone
CAS 37398-31-5C16H15NO3
2-Propen-1-one, 1-(2,4-dimethoxyphenyl)-3-(4-pyridinyl)-, hydrochloride chemical structure, C16H16ClNO3, CAS 65373-34-4
2-Propen-1-one, 1-(2,4-dimethoxyphenyl)-3-(4-pyridinyl)-, hydrochloride
CAS 65373-34-4C16H16ClNO3
2-Propen-1-one, 1-(2,4-dimethoxyphenyl)-3-(4-pyridinyl)-, (Z)-2-butenedioate (2:1) chemical structure, C36H34N2O10, CAS 65373-35-5
2-Propen-1-one, 1-(2,4-dimethoxyphenyl)-3-(4-pyridinyl)-, (Z)-2-butenedioate (2:1)
CAS 65373-35-5C36H34N2O10
Pyridinium, 4-(3-(2,4-dimethoxyphenyl)-3-oxo-1-propenyl)-1-methyl-, iodide chemical structure, C17H18INO3, CAS 65373-37-7
Pyridinium, 4-(3-(2,4-dimethoxyphenyl)-3-oxo-1-propenyl)-1-methyl-, iodide
CAS 65373-37-7C17H18INO3
1-(4-Chlorophenyl)-3-(4-pyridyl)-2-propene-1-one chemical structure, C14H10ClNO, CAS 915145-70-9
1-(4-Chlorophenyl)-3-(4-pyridyl)-2-propene-1-one
CAS 915145-70-9C14H10ClNO
1-(2,4-Dihydroxyphenyl)-3-(pyridin-4-yl)propenone (6) chemical structure, C14H11NO3, CAS 220430-84-2
1-(2,4-Dihydroxyphenyl)-3-(pyridin-4-yl)propenone (6)
CAS 220430-84-2C14H11NO3
(E)-1-(4-Hydroxyphenyl)-3-(pyridin-4-yl)prop-2-en-1-one chemical structure, C14H11NO2, CAS 952577-85-4
(E)-1-(4-Hydroxyphenyl)-3-(pyridin-4-yl)prop-2-en-1-one
CAS 952577-85-4C14H11NO2
2-Propen-1-one, 3-(4-pyridinyl)-1-[3-(trifluoromethyl)phenyl]- chemical structure, C15H10F3NO, CAS 142227-84-7
2-Propen-1-one, 3-(4-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-
CAS 142227-84-7C15H10F3NO
3-(Pyridin-4-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one chemical structure, C17H17NO4, CAS 61196-72-3
3-(Pyridin-4-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
CAS 61196-72-3C17H17NO4
1-(4-Methylphenyl)-3-(4-pyridyl)-2-propene-1-one chemical structure, C15H13NO, CAS 161121-78-4
1-(4-Methylphenyl)-3-(4-pyridyl)-2-propene-1-one
CAS 161121-78-4C15H13NO
1-[4-(Methylsulfanyl)phenyl]-3-(pyridin-4-yl)prop-2-en-1-one chemical structure, C15H13NOS, CAS 95299-25-5
1-[4-(Methylsulfanyl)phenyl]-3-(pyridin-4-yl)prop-2-en-1-one
CAS 95299-25-5C15H13NOS
4-(3-Pyridin-4-ylprop-2-enoyl)benzonitrile chemical structure, C15H10N2O, CAS 159429-65-9
4-(3-Pyridin-4-ylprop-2-enoyl)benzonitrile
CAS 159429-65-9C15H10N2O
1-(4-Propan-2-ylphenyl)-3-pyridin-4-ylprop-2-en-1-one chemical structure, C17H17NO, CAS 208650-90-2
1-(4-Propan-2-ylphenyl)-3-pyridin-4-ylprop-2-en-1-one
CAS 208650-90-2C17H17NO
(2Z)-1-(4-Nitrophenyl)-3-(pyridin-4-yl)prop-2-en-1-one chemical structure, C14H10N2O3, CAS 61196-75-6
(2Z)-1-(4-Nitrophenyl)-3-(pyridin-4-yl)prop-2-en-1-one
CAS 61196-75-6C14H10N2O3
1-(2-Hydroxyphenyl)-3-(pyridin-4-yl)prop-2-en-1-one chemical structure, C14H11NO2, CAS 2875-27-6
1-(2-Hydroxyphenyl)-3-(pyridin-4-yl)prop-2-en-1-one
CAS 2875-27-6C14H11NO2
1-[4-(2,2-Dimethoxyethoxy)phenyl]-3-(pyridin-4-yl)prop-2-en-1-one chemical structure, C18H19NO4, CAS 86041-90-9
1-[4-(2,2-Dimethoxyethoxy)phenyl]-3-(pyridin-4-yl)prop-2-en-1-one
CAS 86041-90-9C18H19NO4