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Murcko scaffold

Ring system with 3 rings and 25 atoms

90 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
90
With full pages
5
Scaffold SMILES

O=C(Oc1ccccc1C(=O)C=Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Oc1ccccc1C(=O)C=Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 90 of 90 chemicals

2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 3-nitrobenzoate chemical structure, C25H21NO8, CAS 433313-04-3
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 3-nitrobenzoate
CAS 433313-04-3C25H21NO8
2-[(2E)-3-(2-Methoxyphenyl)prop-2-enoyl]-4-methylphenyl 3-methoxybenzoate chemical structure, C25H22O5, CAS 433314-10-4
2-[(2E)-3-(2-Methoxyphenyl)prop-2-enoyl]-4-methylphenyl 3-methoxybenzoate
CAS 433314-10-4C25H22O5
4-Bromo-2-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl 3,4-dimethoxybenzoate chemical structure, C25H21BrO6, CAS 433314-57-9
4-Bromo-2-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl 3,4-dimethoxybenzoate
CAS 433314-57-9C25H21BrO6
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 3-methoxybenzoate chemical structure, C24H19FO5, CAS 433314-68-2
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 3-methoxybenzoate
CAS 433314-68-2C24H19FO5
2-[3-(3,4-Dimethoxyphenyl)acryloyl]-4-fluorophenyl 3,4-dimethoxybenzoate chemical structure, C26H23FO7, CAS 1164461-28-2
2-[3-(3,4-Dimethoxyphenyl)acryloyl]-4-fluorophenyl 3,4-dimethoxybenzoate
CAS 1164461-28-2C26H23FO7
[5-Methoxy-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 2-bromobenzoate chemical structure, C24H19BrO5, CAS 433314-90-0
[5-Methoxy-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 2-bromobenzoate
CAS 433314-90-0C24H19BrO5
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 4-methylbenzoate chemical structure, C24H19FO4, CAS 433315-67-4
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 4-methylbenzoate
CAS 433315-67-4C24H19FO4
[5-Methoxy-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 2-methoxybenzoate chemical structure, C25H22O6, CAS 433315-75-4
[5-Methoxy-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 2-methoxybenzoate
CAS 433315-75-4C25H22O6
2-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]-5-methoxyphenyl 3,4-dimethoxybenzoate chemical structure, C25H21ClO6, CAS 433317-87-4
2-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]-5-methoxyphenyl 3,4-dimethoxybenzoate
CAS 433317-87-4C25H21ClO6
2-[(2E)-3-(2-Methoxyphenyl)prop-2-enoyl]-4-methylphenyl 2-bromobenzoate chemical structure, C24H19BrO4, CAS 433312-58-4
2-[(2E)-3-(2-Methoxyphenyl)prop-2-enoyl]-4-methylphenyl 2-bromobenzoate
CAS 433312-58-4C24H19BrO4
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 2-bromobenzoate chemical structure, C25H21BrO6, CAS 433312-93-7
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 2-bromobenzoate
CAS 433312-93-7C25H21BrO6
[4-Bromo-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 2-methoxybenzoate chemical structure, C24H19BrO5, CAS 433313-37-2
[4-Bromo-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 2-methoxybenzoate
CAS 433313-37-2C24H19BrO5
4-Fluoro-2-[(2E)-3-(4-fluorophenyl)prop-2-enoyl]phenyl 3-methoxybenzoate chemical structure, C23H16F2O4, CAS 433314-67-1
4-Fluoro-2-[(2E)-3-(4-fluorophenyl)prop-2-enoyl]phenyl 3-methoxybenzoate
CAS 433314-67-1C23H16F2O4
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-4-fluorophenyl 4-bromobenzoate chemical structure, C24H18BrFO5, CAS 433315-42-5
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-4-fluorophenyl 4-bromobenzoate
CAS 433315-42-5C24H18BrFO5
[5-Methoxy-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 4-bromobenzoate chemical structure, C24H19BrO5, CAS 433317-16-9
[5-Methoxy-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 4-bromobenzoate
CAS 433317-16-9C24H19BrO5
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 2-methoxybenzoate chemical structure, C26H24O7, CAS 433317-44-3
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 2-methoxybenzoate
CAS 433317-44-3C26H24O7
[4-Chloro-2-[(E)-3-(2-fluorophenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate chemical structure, C22H13ClFNO5, CAS 433318-92-4
[4-Chloro-2-[(E)-3-(2-fluorophenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate
CAS 433318-92-4C22H13ClFNO5
2-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]-4-fluorophenyl 4-nitrobenzoate chemical structure, C22H13ClFNO5, CAS 433319-74-5
2-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]-4-fluorophenyl 4-nitrobenzoate
CAS 433319-74-5C22H13ClFNO5
[4-Methyl-2-[(E)-3-(4-methylphenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate chemical structure, C24H19NO5, CAS 433320-87-7
[4-Methyl-2-[(E)-3-(4-methylphenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate
CAS 433320-87-7C24H19NO5
2-[(2E)-3-(4-Chlorophenyl)prop-2-enoyl]-5-methoxyphenyl 3,4-dimethoxybenzoate chemical structure, C25H21ClO6, CAS 433318-43-5
2-[(2E)-3-(4-Chlorophenyl)prop-2-enoyl]-5-methoxyphenyl 3,4-dimethoxybenzoate
CAS 433318-43-5C25H21ClO6
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 4-nitrobenzoate chemical structure, C25H21NO8, CAS 433319-77-8
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 4-nitrobenzoate
CAS 433319-77-8C25H21NO8
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 4-nitrobenzoate chemical structure, C23H16FNO6, CAS 1164453-97-7
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 4-nitrobenzoate
CAS 1164453-97-7C23H16FNO6
[4-Fluoro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 2-methoxybenzoate chemical structure, C24H19FO5, CAS 433320-41-3
[4-Fluoro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 2-methoxybenzoate
CAS 433320-41-3C24H19FO5
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 2-methylbenzoate chemical structure, C26H24O6, CAS 433320-67-3
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-5-methoxyphenyl 2-methylbenzoate
CAS 433320-67-3C26H24O6