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Murcko scaffold

Ring system with 3 rings and 25 atoms

90 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
90
With full pages
5
Scaffold SMILES

O=C(Oc1ccccc1C(=O)C=Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Oc1ccccc1C(=O)C=Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 90 chemicals

2-[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]-4-methylphenyl 2-methoxybenzoate chemical structure, C26H24O6, CAS 433322-16-8
2-[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-yl]-4-methylphenyl 2-methoxybenzoate
CAS 433322-16-8C26H24O6
[5-Methoxy-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 3,4-dimethoxybenzoate chemical structure, C26H24O7, CAS 433247-12-2
[5-Methoxy-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 3,4-dimethoxybenzoate
CAS 433247-12-2C26H24O7
[4-Fluoro-2-[(E)-3-(4-methylphenyl)prop-2-enoyl]phenyl] 4-nitrobenzoate chemical structure, C23H16FNO5, CAS 433248-39-6
[4-Fluoro-2-[(E)-3-(4-methylphenyl)prop-2-enoyl]phenyl] 4-nitrobenzoate
CAS 433248-39-6C23H16FNO5
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 2-methylbenzoate chemical structure, C24H19FO4, CAS 433250-40-9
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 2-methylbenzoate
CAS 433250-40-9C24H19FO4
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 3-nitrobenzoate chemical structure, C23H16FNO6, CAS 433251-71-9
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 3-nitrobenzoate
CAS 433251-71-9C23H16FNO6
[4-Fluoro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate chemical structure, C23H16FNO6, CAS 433252-48-3
[4-Fluoro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate
CAS 433252-48-3C23H16FNO6
5-Methoxy-2-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl benzoate chemical structure, C24H20O5, CAS 433253-33-9
5-Methoxy-2-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl benzoate
CAS 433253-33-9C24H20O5
4-Fluoro-2-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl 2-bromobenzoate chemical structure, C23H16BrFO4, CAS 433253-39-5
4-Fluoro-2-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl 2-bromobenzoate
CAS 433253-39-5C23H16BrFO4
[4-Fluoro-2-[(E)-3-(2-fluorophenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate chemical structure, C22H13F2NO5, CAS 433253-52-2
[4-Fluoro-2-[(E)-3-(2-fluorophenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate
CAS 433253-52-2C22H13F2NO5
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-4-fluorophenyl benzoate chemical structure, C24H19FO5, CAS 433253-66-8
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-4-fluorophenyl benzoate
CAS 433253-66-8C24H19FO5
2-[(2E)-3-(4-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 2-methoxybenzoate chemical structure, C24H19FO5, CAS 433254-05-8
2-[(2E)-3-(4-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 2-methoxybenzoate
CAS 433254-05-8C24H19FO5
[5-Methoxy-2-[(E)-3-(4-methylphenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate chemical structure, C24H19NO6, CAS 433254-55-8
[5-Methoxy-2-[(E)-3-(4-methylphenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate
CAS 433254-55-8C24H19NO6
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 2-bromobenzoate chemical structure, C23H16BrFO4, CAS 433255-14-2
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-5-methoxyphenyl 2-bromobenzoate
CAS 433255-14-2C23H16BrFO4
4-Bromo-2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]phenyl benzoate chemical structure, C24H19BrO5, CAS 433256-89-4
4-Bromo-2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]phenyl benzoate
CAS 433256-89-4C24H19BrO5
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-4-fluorophenyl 4-nitrobenzoate chemical structure, C24H18FNO7, CAS 433258-78-7
2-[(2E)-3-(3,4-Dimethoxyphenyl)prop-2-enoyl]-4-fluorophenyl 4-nitrobenzoate
CAS 433258-78-7C24H18FNO7
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-4-methoxyphenyl 4-nitrobenzoate chemical structure, C23H16FNO6, CAS 433259-36-0
2-[(2E)-3-(2-Fluorophenyl)prop-2-enoyl]-4-methoxyphenyl 4-nitrobenzoate
CAS 433259-36-0C23H16FNO6
[4-Fluoro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 4-nitrobenzoate chemical structure, C23H16FNO6, CAS 433259-48-4
[4-Fluoro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 4-nitrobenzoate
CAS 433259-48-4C23H16FNO6
4-Fluoro-2-[(2E)-3-(4-methylphenyl)prop-2-enoyl]phenyl 2-methoxybenzoate chemical structure, C24H19FO4, CAS 433259-51-9
4-Fluoro-2-[(2E)-3-(4-methylphenyl)prop-2-enoyl]phenyl 2-methoxybenzoate
CAS 433259-51-9C24H19FO4
2-[(2E)-3-(4-Chlorophenyl)prop-2-enoyl]-5-methoxyphenyl 3-nitrobenzoate chemical structure, C23H16ClNO6, CAS 433260-80-1
2-[(2E)-3-(4-Chlorophenyl)prop-2-enoyl]-5-methoxyphenyl 3-nitrobenzoate
CAS 433260-80-1C23H16ClNO6
[4-Chloro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 3-methoxybenzoate chemical structure, C24H19ClO5, CAS 433260-89-0
[4-Chloro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 3-methoxybenzoate
CAS 433260-89-0C24H19ClO5
[4-Chloro-2-[(E)-3-(4-fluorophenyl)prop-2-enoyl]phenyl] 4-nitrobenzoate chemical structure, C22H13ClFNO5, CAS 433260-97-0
[4-Chloro-2-[(E)-3-(4-fluorophenyl)prop-2-enoyl]phenyl] 4-nitrobenzoate
CAS 433260-97-0C22H13ClFNO5
2-[(2E)-3-(2-Methoxyphenyl)prop-2-enoyl]-4-methylphenyl 3-nitrobenzoate chemical structure, C24H19NO6, CAS 433261-20-2
2-[(2E)-3-(2-Methoxyphenyl)prop-2-enoyl]-4-methylphenyl 3-nitrobenzoate
CAS 433261-20-2C24H19NO6
2-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]-4-fluorophenyl 3,4-dimethoxybenzoate chemical structure, C24H18ClFO5, CAS 433261-30-4
2-[(2E)-3-(2-Chlorophenyl)prop-2-enoyl]-4-fluorophenyl 3,4-dimethoxybenzoate
CAS 433261-30-4C24H18ClFO5
[4-Chloro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate chemical structure, C23H16ClNO6, CAS 433305-25-0
[4-Chloro-2-[(E)-3-(2-methoxyphenyl)prop-2-enoyl]phenyl] 3-nitrobenzoate
CAS 433305-25-0C23H16ClNO6