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Murcko scaffold

Ring system with 3 rings and 28 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
28
Chemicals
19
With full pages
10
Scaffold SMILES

O=C(NN=Cc1ccc(OCc2ccccc2)cc1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccc(OCc2ccccc2)cc1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-(2-Ethylphenyl)-N'-[[4-[(3-fluorophenyl)methoxy]phenyl]methylideneamino]oxamide chemical structure, C24H22FN3O3, CAS 6171-86-4
N-(2-Ethylphenyl)-N'-[[4-[(3-fluorophenyl)methoxy]phenyl]methylideneamino]oxamide
CAS 6171-86-4C24H22FN3O3
N'-[[4-[(2,6-Dichlorophenyl)methoxy]-3-methoxyphenyl]methylideneamino]-N-(2,5-dimethylphenyl)oxamide chemical structure, C25H23Cl2N3O4, CAS 6172-13-0
N'-[[4-[(2,6-Dichlorophenyl)methoxy]-3-methoxyphenyl]methylideneamino]-N-(2,5-dimethylphenyl)oxamide
CAS 6172-13-0C25H23Cl2N3O4
N-(4-Acetamidophenyl)-N'-[[4-[(3-chlorophenyl)methoxy]-3-ethoxyphenyl]methylideneamino]oxamide chemical structure, C26H25ClN4O5, CAS 6173-31-5
N-(4-Acetamidophenyl)-N'-[[4-[(3-chlorophenyl)methoxy]-3-ethoxyphenyl]methylideneamino]oxamide
CAS 6173-31-5C26H25ClN4O5
N-(2,5-Dimethoxyphenyl)-N'-[(E)-(4-phenylmethoxyphenyl)methylideneamino]oxamide chemical structure, C24H23N3O5, CAS 352014-03-0
N-(2,5-Dimethoxyphenyl)-N'-[(E)-(4-phenylmethoxyphenyl)methylideneamino]oxamide
CAS 352014-03-0C24H23N3O5
2-(2-(4-((4-CL-Benzyl)oxy)benzylidene)hydrazino)-N-(4-ethoxy-PH)-2-oxoacetamide chemical structure, C24H22ClN3O4, CAS 330990-90-4
2-(2-(4-((4-CL-Benzyl)oxy)benzylidene)hydrazino)-N-(4-ethoxy-PH)-2-oxoacetamide
CAS 330990-90-4C24H22ClN3O4
2-{(2E)-2-[4-(Benzyloxy)benzylidene]hydrazino}-N-(2-methylphenyl)-2-oxoacetamide chemical structure, C23H21N3O3, CAS 339251-00-2
2-{(2E)-2-[4-(Benzyloxy)benzylidene]hydrazino}-N-(2-methylphenyl)-2-oxoacetamide
CAS 339251-00-2C23H21N3O3
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(4-ethylphenyl)-2-oxoacetamide chemical structure, C24H23N3O3, CAS 339254-25-0
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(4-ethylphenyl)-2-oxoacetamide
CAS 339254-25-0C24H23N3O3
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(3-methoxyphenyl)-2-oxoacetamide chemical structure, C23H21N3O4, CAS 357412-73-8
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(3-methoxyphenyl)-2-oxoacetamide
CAS 357412-73-8C23H21N3O4
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(4-methylphenyl)-2-oxoacetamide chemical structure, C23H21N3O3, CAS 357412-01-2
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(4-methylphenyl)-2-oxoacetamide
CAS 357412-01-2C23H21N3O3
2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxo-N-phenylacetamide chemical structure, C23H21N3O3, CAS 769156-38-9
2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxo-N-phenylacetamide
CAS 769156-38-9C23H21N3O3
2-(2-(4-((4-CL-Benzyl)oxy)benzylidene)hydrazino)-N-(3-CL-4-ME-PH)-2-oxoacetamide chemical structure, C23H19Cl2N3O3, CAS 767302-28-3
2-(2-(4-((4-CL-Benzyl)oxy)benzylidene)hydrazino)-N-(3-CL-4-ME-PH)-2-oxoacetamide
CAS 767302-28-3C23H19Cl2N3O3
N-(4-CL-PH)-2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoacetamide chemical structure, C23H20ClN3O3, CAS 767306-48-9
N-(4-CL-PH)-2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoacetamide
CAS 767306-48-9C23H20ClN3O3
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(3,4-dichlorophenyl)-2-oxoacetamide chemical structure, C22H17Cl2N3O3, CAS 357412-55-6
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(3,4-dichlorophenyl)-2-oxoacetamide
CAS 357412-55-6C22H17Cl2N3O3
N-(3-Chloro-2-methylphenyl)-2-(2-(4-((4-methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoacetamide chemical structure, C24H22ClN3O3, CAS 882046-84-6
N-(3-Chloro-2-methylphenyl)-2-(2-(4-((4-methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoacetamide
CAS 882046-84-6C24H22ClN3O3
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(4-methoxyphenyl)-2-oxoacetamide chemical structure, C23H21N3O4, CAS 357412-82-9
2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-N-(4-methoxyphenyl)-2-oxoacetamide
CAS 357412-82-9C23H21N3O4
2-[(4-Chlorophenyl)amino]-2-oxoacetic acid 2-[[4-[(2,6-dichlorophenyl)methoxy]-3-ethoxyphenyl]methylene]hydrazide chemical structure, C24H20Cl3N3O4, CAS 885532-48-9
2-[(4-Chlorophenyl)amino]-2-oxoacetic acid 2-[[4-[(2,6-dichlorophenyl)methoxy]-3-ethoxyphenyl]methylene]hydrazide
CAS 885532-48-9C24H20Cl3N3O4
2-[(3,4-Dimethylphenyl)amino]-2-oxoacetic acid 2-[[4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl]methylene]hydrazide chemical structure, C25H23Cl2N3O4, CAS 885532-53-6
2-[(3,4-Dimethylphenyl)amino]-2-oxoacetic acid 2-[[4-[(2,4-dichlorophenyl)methoxy]-3-methoxyphenyl]methylene]hydrazide
CAS 885532-53-6C25H23Cl2N3O4
2-[(2,3-Dichlorophenyl)amino]-2-oxoacetic acid 2-[[4-[(4-chlorophenyl)methoxy]-3-ethoxyphenyl]methylene]hydrazide chemical structure, C24H20Cl3N3O4, CAS 885531-06-6
2-[(2,3-Dichlorophenyl)amino]-2-oxoacetic acid 2-[[4-[(4-chlorophenyl)methoxy]-3-ethoxyphenyl]methylene]hydrazide
CAS 885531-06-6C24H20Cl3N3O4
2-(2-{[4-(Benzyloxy)-3-ethoxyphenyl]methylidene}hydrazinyl)-N-(2-fluorophenyl)-2-oxoacetamide chemical structure, C24H22FN3O4, CAS 885167-94-2
2-(2-{[4-(Benzyloxy)-3-ethoxyphenyl]methylidene}hydrazinyl)-N-(2-fluorophenyl)-2-oxoacetamide
CAS 885167-94-2C24H22FN3O4