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Murcko scaffold

Ring system with 3 rings and 29 atoms

197 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
29
Chemicals
197
With full pages
187
Scaffold SMILES

O=C(NN=Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 197 chemicals

4-(2-((2,3-Dichloroanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-butoxybenzoate chemical structure, C26H23Cl2N3O5, CAS 477732-57-3
4-(2-((2,3-Dichloroanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-butoxybenzoate
CAS 477732-57-3C26H23Cl2N3O5
[4-[N-[[2-(3,4-Dichloroanilino)-2-oxoacetyl]amino]-C-methylcarbonimidoyl]phenyl] 4-methoxybenzoate chemical structure, C24H19Cl2N3O5, CAS 6174-25-0
[4-[N-[[2-(3,4-Dichloroanilino)-2-oxoacetyl]amino]-C-methylcarbonimidoyl]phenyl] 4-methoxybenzoate
CAS 6174-25-0C24H19Cl2N3O5
[4-[[[2-(3-Methylanilino)-2-oxoacetyl]hydrazinylidene]methyl]phenyl] 2-iodobenzoate chemical structure, C23H18IN3O4, CAS 6647-17-2
[4-[[[2-(3-Methylanilino)-2-oxoacetyl]hydrazinylidene]methyl]phenyl] 2-iodobenzoate
CAS 6647-17-2C23H18IN3O4
4-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-propoxybenzoate chemical structure, C27H27N3O5, CAS 767312-05-0
4-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-propoxybenzoate
CAS 767312-05-0C27H27N3O5
4-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C23H18ClN3O5, CAS 601500-21-4
4-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 601500-21-4C23H18ClN3O5
4-((E)-{[(4-Chloroanilino)(oxo)acetyl]hydrazono}methyl)-2-methoxyphenyl 3-bromobenzoate chemical structure, C23H17BrClN3O5, CAS 477730-78-2
4-((E)-{[(4-Chloroanilino)(oxo)acetyl]hydrazono}methyl)-2-methoxyphenyl 3-bromobenzoate
CAS 477730-78-2C23H17BrClN3O5
4-(2-((4-Fluoroanilino)(oxo)AC)carbohydrazonoyl)-2-methoxyphenyl 3-bromobenzoate chemical structure, C23H17BrFN3O5, CAS 477730-25-9
4-(2-((4-Fluoroanilino)(oxo)AC)carbohydrazonoyl)-2-methoxyphenyl 3-bromobenzoate
CAS 477730-25-9C23H17BrFN3O5
4-(2-((3-CL-2-Methylanilino)(oxo)AC)carbohydrazonoyl)-2-meo-PH 3-bromobenzoate chemical structure, C24H19BrClN3O5, CAS 477730-20-4
4-(2-((3-CL-2-Methylanilino)(oxo)AC)carbohydrazonoyl)-2-meo-PH 3-bromobenzoate
CAS 477730-20-4C24H19BrClN3O5
2-Ethoxy-4-(2-((3-methoxyanilino)(oxo)AC)carbohydrazonoyl)PH 4-chlorobenzoate chemical structure, C25H22ClN3O6, CAS 769149-58-8
2-Ethoxy-4-(2-((3-methoxyanilino)(oxo)AC)carbohydrazonoyl)PH 4-chlorobenzoate
CAS 769149-58-8C25H22ClN3O6
4-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 3-chlorobenzoate chemical structure, C23H18ClN3O5, CAS 595551-32-9
4-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 3-chlorobenzoate
CAS 595551-32-9C23H18ClN3O5
2-Methoxy-4-(2-(oxo(4-toluidino)acetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate chemical structure, C26H25N3O6, CAS 769149-71-5
2-Methoxy-4-(2-(oxo(4-toluidino)acetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate
CAS 769149-71-5C26H25N3O6
4-(2-((2,3-Dichloroanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-bromobenzoate chemical structure, C22H14BrCl2N3O4, CAS 477732-59-5
4-(2-((2,3-Dichloroanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-bromobenzoate
CAS 477732-59-5C22H14BrCl2N3O4
2-Methoxy-4-(2-((4-methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-methylbenzoate chemical structure, C25H23N3O6, CAS 597547-21-2
2-Methoxy-4-(2-((4-methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 4-methylbenzoate
CAS 597547-21-2C25H23N3O6
4-((E)-{[(4-Bromoanilino)(oxo)acetyl]hydrazono}methyl)-2-methoxyphenyl 3-bromobenzoate chemical structure, C23H17Br2N3O5, CAS 767302-13-6
4-((E)-{[(4-Bromoanilino)(oxo)acetyl]hydrazono}methyl)-2-methoxyphenyl 3-bromobenzoate
CAS 767302-13-6C23H17Br2N3O5
2-Ethoxy-4-(2-((3-methoxyanilino)(oxo)AC)carbohydrazonoyl)PH 4-methoxybenzoate chemical structure, C26H25N3O7, CAS 769148-55-2
2-Ethoxy-4-(2-((3-methoxyanilino)(oxo)AC)carbohydrazonoyl)PH 4-methoxybenzoate
CAS 769148-55-2C26H25N3O7
4-(2-((3-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C23H17Cl2N3O5, CAS 769148-29-0
4-(2-((3-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 769148-29-0C23H17Cl2N3O5
4-(2-((3,4-Dichloroanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2-bromobenzoate chemical structure, C22H14BrCl2N3O4, CAS 769149-31-7
4-(2-((3,4-Dichloroanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2-bromobenzoate
CAS 769149-31-7C22H14BrCl2N3O4
4-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 3-chlorobenzoate chemical structure, C24H20ClN3O4, CAS 765284-60-4
4-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 3-chlorobenzoate
CAS 765284-60-4C24H20ClN3O4
4-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C23H17Cl2N3O5, CAS 769148-22-3
4-(2-((4-Methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 769148-22-3C23H17Cl2N3O5
2-Ethoxy-4-(2-((4-methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl benzoate chemical structure, C25H23N3O6, CAS 769156-94-7
2-Ethoxy-4-(2-((4-methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenyl benzoate
CAS 769156-94-7C25H23N3O6
2-Methoxy-4-(2-(oxo(2-toluidino)acetyl)carbohydrazonoyl)phenyl 3-bromobenzoate chemical structure, C24H20BrN3O5, CAS 764657-07-0
2-Methoxy-4-(2-(oxo(2-toluidino)acetyl)carbohydrazonoyl)phenyl 3-bromobenzoate
CAS 764657-07-0C24H20BrN3O5
4-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C24H19Cl2N3O4, CAS 769153-76-6
4-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 769153-76-6C24H19Cl2N3O4
2-Ethoxy-4-((E)-{[(3-methoxyanilino)(oxo)acetyl]hydrazono}methyl)phenyl 4-ethoxybenzoate chemical structure, C27H27N3O7, CAS 769156-40-3
2-Ethoxy-4-((E)-{[(3-methoxyanilino)(oxo)acetyl]hydrazono}methyl)phenyl 4-ethoxybenzoate
CAS 769156-40-3C27H27N3O7
2-Meo-4-(2-((3-methoxyanilino)(oxo)AC)carbohydrazonoyl)PH 3,4-dichlorobenzoate chemical structure, C24H19Cl2N3O6, CAS 769147-51-5
2-Meo-4-(2-((3-methoxyanilino)(oxo)AC)carbohydrazonoyl)PH 3,4-dichlorobenzoate
CAS 769147-51-5C24H19Cl2N3O6