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Murcko scaffold

4-Phenoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide scaffold

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
29
Chemicals
13
With full pages
2
Scaffold SMILES

O=C(CCCOc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide page
Murcko scaffold O=C(CCCOc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

4-Phenoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C20H20N4O4S, CAS 383894-31-3
4-Phenoxy-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 383894-31-3C20H20N4O4S
4-(2,4-Dichlorophenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C20H18Cl2N4O4S, CAS 370572-47-7
4-(2,4-Dichlorophenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 370572-47-7C20H18Cl2N4O4S
4-(2-Methylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C21H22N4O4S, CAS 370849-80-2
4-(2-Methylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 370849-80-2C21H22N4O4S
4-(4-Methylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C21H22N4O4S, CAS 369396-60-1
4-(4-Methylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 369396-60-1C21H22N4O4S
4-(4-Ethylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C22H24N4O4S, CAS 384358-73-0
4-(4-Ethylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 384358-73-0C22H24N4O4S
4-(4-tert-Butylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C24H28N4O4S, CAS 442150-73-4
4-(4-tert-Butylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 442150-73-4C24H28N4O4S
4-(4-Chlorophenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C20H19ClN4O4S, CAS 371201-10-4
4-(4-Chlorophenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 371201-10-4C20H19ClN4O4S
4-(4-Chlorophenoxy)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}butanamide chemical structure, C22H23ClN4O4S, CAS 371115-63-8
4-(4-Chlorophenoxy)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}butanamide
CAS 371115-63-8C22H23ClN4O4S
N-[4-(Pyrimidin-2-ylsulfamoyl)-phenyl]-4-m-tolyloxy-butyramide chemical structure, C21H22N4O4S, CAS 432536-70-4
N-[4-(Pyrimidin-2-ylsulfamoyl)-phenyl]-4-m-tolyloxy-butyramide
CAS 432536-70-4C21H22N4O4S
4-(4-Methoxyphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C21H22N4O5S, CAS 459418-38-3
4-(4-Methoxyphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 459418-38-3C21H22N4O5S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-(4-methoxyphenoxy)butanamide chemical structure, C23H26N4O5S, CAS 459418-39-4
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-4-(4-methoxyphenoxy)butanamide
CAS 459418-39-4C23H26N4O5S
4-(2,4-Dichlorophenoxy)-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]butanamide chemical structure, C21H20Cl2N4O4S, CAS 314022-53-2
4-(2,4-Dichlorophenoxy)-N-[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]butanamide
CAS 314022-53-2C21H20Cl2N4O4S
4-(4-Chloro-2-methylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide chemical structure, C21H21ClN4O4S, CAS 505088-34-6
4-(4-Chloro-2-methylphenoxy)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]butanamide
CAS 505088-34-6C21H21ClN4O4S