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Murcko scaffold

4-(3-Thienyl)pyrimidine scaffold

99 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
99
With full pages
3
Scaffold SMILES

c1cc(-c2ccsc2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(3-Thienyl)pyrimidine page
Murcko scaffold c1cc(-c2ccsc2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 99 chemicals

4-(2,5-Dichloro-thiophen-3-yl)-pyrimidin-2-ylamine chemical structure, C8H5Cl2N3S, CAS 566149-73-3
4-(2,5-Dichloro-thiophen-3-yl)-pyrimidin-2-ylamine
CAS 566149-73-3C8H5Cl2N3S
4-(3-Thienyl)pyrimidine chemical structure, C8H6N2S, CAS 19084-28-7
4-(3-Thienyl)pyrimidine
CAS 19084-28-7C8H6N2S
4-(2,5-Dichloro-3-thienyl)-2-pyrimidinyl methyl sulfide chemical structure, C9H6Cl2N2S2, CAS 339020-26-7
4-(2,5-Dichloro-3-thienyl)-2-pyrimidinyl methyl sulfide
CAS 339020-26-7C9H6Cl2N2S2
4-(3-Thienyl)-2-pyrimidinamine chemical structure, C8H7N3S, CAS 206564-03-6
4-(3-Thienyl)-2-pyrimidinamine
CAS 206564-03-6C8H7N3S
4-Methyl-6-(3-thienyl)-2-pyrimidinamine chemical structure, C9H9N3S, CAS 885950-01-6
4-Methyl-6-(3-thienyl)-2-pyrimidinamine
CAS 885950-01-6C9H9N3S
4-(2-Methylsulfanylpyrimidin-4-yl)thiophene-2-sulfonyl chloride chemical structure, C9H7ClN2O2S3, CAS 874841-65-3
4-(2-Methylsulfanylpyrimidin-4-yl)thiophene-2-sulfonyl chloride
CAS 874841-65-3C9H7ClN2O2S3
2-(Allylsulfanyl)-4-(2,5-dichloro-3-thienyl)pyrimidine chemical structure, C11H8Cl2N2S2, CAS 339106-59-1
2-(Allylsulfanyl)-4-(2,5-dichloro-3-thienyl)pyrimidine
CAS 339106-59-1C11H8Cl2N2S2
4-(2,5-Dimethylthiophen-3-yl)pyrimidin-2-amine chemical structure, C10H11N3S, CAS 364334-90-7
4-(2,5-Dimethylthiophen-3-yl)pyrimidin-2-amine
CAS 364334-90-7C10H11N3S
2-{[4-(2,5-Dichloro-3-thienyl)-2-pyrimidinyl]sulfanyl}acetonitrile chemical structure, C10H5Cl2N3S2, CAS 339106-55-7
2-{[4-(2,5-Dichloro-3-thienyl)-2-pyrimidinyl]sulfanyl}acetonitrile
CAS 339106-55-7C10H5Cl2N3S2
4-{2,5-Bisnitro-3-thienyl}pyrimidine chemical structure, C8H4N4O4S, CAS 19084-34-5
4-{2,5-Bisnitro-3-thienyl}pyrimidine
CAS 19084-34-5C8H4N4O4S
2-Chloro-4-(thiophen-3-yl)pyrimidine chemical structure, C8H5ClN2S, CAS 63558-68-9
2-Chloro-4-(thiophen-3-yl)pyrimidine
CAS 63558-68-9C8H5ClN2S
[4-(Thiophen-3-yl)pyrimidin-2-yl]cyanamide chemical structure, C9H6N4S, CAS 1144453-01-9
[4-(Thiophen-3-yl)pyrimidin-2-yl]cyanamide
CAS 1144453-01-9C9H6N4S
4-Bromo-6-(thiophen-3-yl)pyrimidine chemical structure, C8H5BrN2S, CAS 1086382-34-4
4-Bromo-6-(thiophen-3-yl)pyrimidine
CAS 1086382-34-4C8H5BrN2S
4-Amino-6-(3-thienyl)pyrimidine chemical structure, C8H7N3S, CAS 1159818-42-4
4-Amino-6-(3-thienyl)pyrimidine
CAS 1159818-42-4C8H7N3S
Ethyl 2-hydrazinyl-4-thiophen-3-ylpyrimidine-5-carboxylate chemical structure, C11H12N4O2S, CAS 188937-73-7
Ethyl 2-hydrazinyl-4-thiophen-3-ylpyrimidine-5-carboxylate
CAS 188937-73-7C11H12N4O2S
4-(2,5-Dimethyl-3-thienyl)-2-hydrazinopyrimidine chemical structure, C10H12N4S, CAS 1308384-61-3
4-(2,5-Dimethyl-3-thienyl)-2-hydrazinopyrimidine
CAS 1308384-61-3C10H12N4S
Pyrimidine, 4-chloro-6-(3-thienyl)- chemical structure, C8H5ClN2S, CAS 898546-96-8
Pyrimidine, 4-chloro-6-(3-thienyl)-
CAS 898546-96-8C8H5ClN2S
[4-(2-Chloropyrimidin-4-yl)thiophen-2-yl]methanol chemical structure, C9H7ClN2OS, CAS 937273-40-0
[4-(2-Chloropyrimidin-4-yl)thiophen-2-yl]methanol
CAS 937273-40-0C9H7ClN2OS
4-(5-Allyloxymethylthiophen-3-yl)-2-chloropyrimidine chemical structure, C12H11ClN2OS, CAS 937273-41-1
4-(5-Allyloxymethylthiophen-3-yl)-2-chloropyrimidine
CAS 937273-41-1C12H11ClN2OS
4-(2-Chloropyrimidin-4-yl)thiophene-2-carbaldehyde chemical structure, C9H5ClN2OS, CAS 937273-39-7
4-(2-Chloropyrimidin-4-yl)thiophene-2-carbaldehyde
CAS 937273-39-7C9H5ClN2OS
4-(Pyrimidin-4-yl)thiophen-2-amine chemical structure, C8H7N3S, CAS 692891-75-1
4-(Pyrimidin-4-yl)thiophen-2-amine
CAS 692891-75-1C8H7N3S
4-(5-Nitro-thiophen-3-yl)-pyrimidine chemical structure, C8H5N3O2S, CAS 17808-16-1
4-(5-Nitro-thiophen-3-yl)-pyrimidine
CAS 17808-16-1C8H5N3O2S
4-Amino-2-methyl-6-(3-thienyl)pyrimidine chemical structure, C9H9N3S, CAS 1412957-83-5
4-Amino-2-methyl-6-(3-thienyl)pyrimidine
CAS 1412957-83-5C9H9N3S
4-Chloro-2-methyl-6-(thiophen-3-yl)pyrimidine chemical structure, C9H7ClN2S, CAS 1412958-70-3
4-Chloro-2-methyl-6-(thiophen-3-yl)pyrimidine
CAS 1412958-70-3C9H7ClN2S