Murcko scaffold
1-Benzyl-2-(phenoxymethyl)benzimidazole scaffold
53 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 24
- Chemicals
- 53
- With full pages
- 10
Scaffold SMILES
c1ccc(Cn2c(COc3ccccc3)nc3ccccc32)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 53 chemicals
1-(2-Fluoro-benzyl)-2-phenoxymethyl-1H-benzoimidazole
CAS 431892-15-8C21H17FN2O
![1-Benzyl-2-[(2-methoxyphenoxy)methyl]benzimidazole chemical structure, C22H20N2O2, CAS 510723-45-2](/s/REHHWBWTFZUYTA-UHFFFAOYSA-N.svg)
1-Benzyl-2-[(2-methoxyphenoxy)methyl]benzimidazole
CAS 510723-45-2C22H20N2O2
![1-[(2-Chlorophenyl)methyl]-2-(phenoxymethyl)benzimidazole chemical structure, C21H17ClN2O, CAS 443328-77-6](/s/VVFLDMPVXJYJMH-UHFFFAOYSA-N.svg)
1-[(2-Chlorophenyl)methyl]-2-(phenoxymethyl)benzimidazole
CAS 443328-77-6C21H17ClN2O
![1-(2-Methylbenzyl)-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole chemical structure, C23H22N2O, CAS 537018-35-2](/s/XOMXKDUZVJLCPC-UHFFFAOYSA-N.svg)
1-(2-Methylbenzyl)-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole
CAS 537018-35-2C23H22N2O
![1-Benzyl-2-[(4-chlorophenoxy)methyl]benzimidazole chemical structure, C21H17ClN2O, CAS 612049-70-4](/s/VNOJQXZUQYWAJF-UHFFFAOYSA-N.svg)
1-Benzyl-2-[(4-chlorophenoxy)methyl]benzimidazole
CAS 612049-70-4C21H17ClN2O
![1-(4-Methylbenzyl)-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole chemical structure, C23H22N2O, CAS 537009-30-6](/s/ISWTWYDNUZQCAG-UHFFFAOYSA-N.svg)
1-(4-Methylbenzyl)-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole
CAS 537009-30-6C23H22N2O
![1-(3-Methylbenzyl)-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole chemical structure, C23H22N2O, CAS 537017-87-1](/s/KQKJZJYDHLAJOQ-UHFFFAOYSA-N.svg)
1-(3-Methylbenzyl)-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole
CAS 537017-87-1C23H22N2O
1-Benzyl-2-(phenoxymethyl)benzimidazole
CAS 333746-94-4C21H18N2O
1-(4-Methylbenzyl)-2-(phenoxymethyl)-1H-benzimidazole
CAS 612049-43-1C22H20N2O
1-(2-Methoxybenzyl)-2-(phenoxymethyl)-1H-benzimidazole
CAS 488088-94-4C22H20N2O2
![1-Benzyl-2-[(4-methoxyphenoxy)methyl]-1H-1,3-benzodiazole chemical structure, C22H20N2O2, CAS 441291-98-1](/s/VWWUDTPFMACIAU-UHFFFAOYSA-N.svg)
1-Benzyl-2-[(4-methoxyphenoxy)methyl]-1H-1,3-benzodiazole
CAS 441291-98-1C22H20N2O2
![1-Benzyl-2-[(2-methylphenoxy)methyl]benzimidazole chemical structure, C22H20N2O, CAS 612049-77-1](/s/SWQBRSOGPYAELF-UHFFFAOYSA-N.svg)
1-Benzyl-2-[(2-methylphenoxy)methyl]benzimidazole
CAS 612049-77-1C22H20N2O
![1-Benzyl-2-[(4-methylphenoxy)methyl]benzimidazole chemical structure, C22H20N2O, CAS 433328-10-0](/s/XKBYZWVSZHLMEO-UHFFFAOYSA-N.svg)
1-Benzyl-2-[(4-methylphenoxy)methyl]benzimidazole
CAS 433328-10-0C22H20N2O
![1-Benzyl-2-[(4-fluorophenoxy)methyl]-1H-benzimidazole chemical structure, C21H17FN2O, CAS 713080-49-0](/s/OEOHINWMPCBHGT-UHFFFAOYSA-N.svg)
1-Benzyl-2-[(4-fluorophenoxy)methyl]-1H-benzimidazole
CAS 713080-49-0C21H17FN2O
![1-Benzyl-2-[(3-methylphenoxy)methyl]-1H-benzimidazole chemical structure, C22H20N2O, CAS 713080-50-3](/s/HROVCYNHBCGVQC-UHFFFAOYSA-N.svg)
1-Benzyl-2-[(3-methylphenoxy)methyl]-1H-benzimidazole
CAS 713080-50-3C22H20N2O
![2-((2-Methoxyphenoxy)methyl)-1-(4-methylbenzyl)-1H-benzo[d]imidazole chemical structure, C23H22N2O2, CAS 433330-06-4](/s/QSTZKFZJMSLJHQ-UHFFFAOYSA-N.svg)
2-((2-Methoxyphenoxy)methyl)-1-(4-methylbenzyl)-1H-benzo[d]imidazole
CAS 433330-06-4C23H22N2O2
![1-[(2,4-Dichlorophenyl)methyl]-2-[(2-methoxyphenoxy)methyl]benzimidazole chemical structure, C22H18Cl2N2O2, CAS 433701-24-7](/s/GLLSSHGGMXKFJT-UHFFFAOYSA-N.svg)
1-[(2,4-Dichlorophenyl)methyl]-2-[(2-methoxyphenoxy)methyl]benzimidazole
CAS 433701-24-7C22H18Cl2N2O2
![2-((4-Chlorophenoxy)methyl)-1-(3-methylbenzyl)-1H-benzo[d]imidazole chemical structure, C22H19ClN2O, CAS 537017-89-3](/s/IHVWUXSQAANWSO-UHFFFAOYSA-N.svg)
2-((4-Chlorophenoxy)methyl)-1-(3-methylbenzyl)-1H-benzo[d]imidazole
CAS 537017-89-3C22H19ClN2O
![2-((4-Chlorophenoxy)methyl)-1-(2-methylbenzyl)-1H-benzo[d]imidazole chemical structure, C22H19ClN2O, CAS 537017-96-2](/s/NEKJHZGWSNLKGX-UHFFFAOYSA-N.svg)
2-((4-Chlorophenoxy)methyl)-1-(2-methylbenzyl)-1H-benzo[d]imidazole
CAS 537017-96-2C22H19ClN2O
![2-((4-Chlorophenoxy)methyl)-1-(4-fluorobenzyl)-1H-benzo[d]imidazole chemical structure, C21H16ClFN2O, CAS 537701-79-4](/s/QJJFGVPVTOHCIZ-UHFFFAOYSA-N.svg)
2-((4-Chlorophenoxy)methyl)-1-(4-fluorobenzyl)-1H-benzo[d]imidazole
CAS 537701-79-4C21H16ClFN2O
![1-[(2-Fluorophenyl)methyl]-2-[(4-methoxyphenoxy)methyl]benzimidazole chemical structure, C22H19FN2O2, CAS 638140-24-6](/s/SVQCGARLNBTNMM-UHFFFAOYSA-N.svg)
1-[(2-Fluorophenyl)methyl]-2-[(4-methoxyphenoxy)methyl]benzimidazole
CAS 638140-24-6C22H19FN2O2
1-((2-Chloro-6-fluorophenyl)methyl)-2-((2-methoxyphenoxy)methyl)-1H-benzimidazole
CAS 638140-69-9C22H18ClFN2O2
![2-[(4-Chlorophenoxy)methyl]-1-[(4-methylphenyl)methyl]benzimidazole chemical structure, C22H19ClN2O, CAS 433698-60-3](/s/XFHHFGRXDOCUNV-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenoxy)methyl]-1-[(4-methylphenyl)methyl]benzimidazole
CAS 433698-60-3C22H19ClN2O
![1-(2-Chlorobenzyl)-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole chemical structure, C22H19ClN2O, CAS 433702-71-7](/s/FBJZAQSBDQXGRL-UHFFFAOYSA-N.svg)
1-(2-Chlorobenzyl)-2-((p-tolyloxy)methyl)-1H-benzo[d]imidazole
CAS 433702-71-7C22H19ClN2O
- 1-(2-Chlorobenzyl)-2-((4-methoxyphenoxy)methyl)-1H-benzo[d]imidazole432015-28-6C22H19ClN2O2
- 2-[(4-Methoxyphenoxy)methyl]-1-[(4-methylphenyl)methyl]benzimidazole429656-35-9C23H22N2O2
- 1-[(2-Chloro-6-fluorophenyl)methyl]-2-[(4-methoxyphenoxy)methyl]benzimidazole638140-25-7C22H18ClFN2O2
- 2-[(4-tert-Butylphenoxy)methyl]-1-[(3,4-dimethoxyphenyl)methyl]benzimidazole638140-38-2C27H30N2O3
- 1-[(2,4-Dichlorophenyl)methyl]-2-[(4-methoxyphenoxy)methyl]benzimidazole1260674-05-2C22H18Cl2N2O2
- 1-(2-Chlorobenzyl)-2-((2-methoxyphenoxy)methyl)-1H-benzo[d]imidazole612049-75-9C22H19ClN2O2
- 1-(3,4-Dimethoxybenzyl)-2-(phenoxymethyl)-1H-benzo[d]imidazole488842-84-8C23H22N2O3
- 2-[(4-Methoxyphenoxy)methyl]-1-(1-phenylethyl)benzimidazole385373-86-4C23H22N2O2
- 2-[(4-Chlorophenoxy)methyl]-1-(1-phenylethyl)-1H-benzimidazole433698-52-3C22H19ClN2O
- 2-[(4-Methylphenoxy)methyl]-1-(1-phenylethyl)benzimidazole537009-26-0C23H22N2O
- 2-(Phenoxymethyl)-1-(1-phenylethyl)-1H-benzo[d]imidazole380575-07-5C22H20N2O
- 2-((4-(tert-Butyl)phenoxy)methyl)-1-(4-fluorobenzyl)-1H-benzo[d]imidazole615280-79-0C25H25FN2O
- 2-((4-(tert-Butyl)phenoxy)methyl)-1-(4-methoxybenzyl)-1H-benzo[d]imidazole638140-39-3C26H28N2O2
- 2-((2,4-Dichlorophenoxy)methyl)-1-(1-phenylethyl)-1H-benzo[d]imidazole477544-03-9C22H18Cl2N2O
- 1-(4-Butoxybenzyl)-2-((4-(tert-butyl)phenoxy)methyl)-1H-benzo[d]imidazole796876-95-4C29H34N2O2
- 2-((4-(tert-Butyl)phenoxy)methyl)-1-(4-chlorobenzyl)-1H-benzo[d]imidazole615280-78-9C25H25ClN2O
- 1-[(4-Methylphenyl)methyl]-2-[(5-methyl-2-propan-2-ylphenoxy)methyl]benzimidazole380352-62-5C26H28N2O
- 2-((4-(tert-Butyl)phenoxy)methyl)-1-(2-chlorobenzyl)-1H-benzo[d]imidazole615280-76-7C25H25ClN2O
- 2-((4-(tert-Butyl)phenoxy)methyl)-1-(4-methylbenzyl)-1H-benzo[d]imidazole615280-80-3C26H28N2O
- 2-((4-(tert-Butyl)phenoxy)methyl)-1-(3-methylbenzyl)-1H-benzo[d]imidazole638140-37-1C26H28N2O
- 2-((4-(tert-Butyl)phenoxy)methyl)-1-(4-isopropylbenzyl)-1H-benzo[d]imidazole796880-33-6C28H32N2O
- 1-Benzyl-2-[(2,4-dichlorophenoxy)methyl]benzimidazole476324-63-7C21H16Cl2N2O
- 1-(4-tert-Butylbenzyl)-2-[(4-methoxyphenoxy)methyl]-1H-benzimidazole384358-98-9C26H28N2O2
- 2-[(2-Methoxyphenoxy)methyl]-1-[(2-methoxyphenyl)methyl]benzimidazole880622-57-1C23H22N2O3
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1[nH]c(=O)c2c(nc(NCc3ccccc3)n2Cc2ccccc2)[nH]1](/scaffold/PFBIFWAJSJQHQA-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(nc(NCc3ccccc3)n2Cc2ccccc2)[nH]120 chemicals![Scaffold O=c1[nH]c(=O)c2c(nc(SCc3ccccc3)n2Cc2ccccc2)[nH]1](/scaffold/IZIYKKZRUBZGEM-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(nc(SCc3ccccc3)n2Cc2ccccc2)[nH]14 chemicals![Scaffold O=c1[nH]c(=O)c2c(nc(OCc3cccnc3)n2Cc2ccccc2)[nH]1](/scaffold/AWZSXSWUZGAPLT-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(nc(OCc3cccnc3)n2Cc2ccccc2)[nH]11 chemical
O=C(c1ccccc1)n1c(SCc2ccccc2)nc2ccccc211 chemical
O=C(Nc1sc2c(c1C(=O)N1CCOCC1)CCCC2)c1ccccc11 chemical
O=C(Nc1nc2ccccc2n1Cc1ccccc1)C1CCCCC11 chemical![Scaffold O=c1[nH]c(=O)c2c(nc(N=Cc3ccccc3)n2Cc2ccccc2)[nH]1](/scaffold/KKTANWOGAHHUPP-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(nc(N=Cc3ccccc3)n2Cc2ccccc2)[nH]11 chemical
O=C(Nc1sc2c(c1C(=O)N1CCCCC1)CCCC2)c1ccccc11 chemical
c1ccc(CNc2nc3ccccc3n2Cc2ccccc2)cc11 chemical
C(=Cc1nc2ccccc2n1Cc1ccccc1)c1ccccc11 chemical
O=S(=O)(Nc1nc2ccccc2n1Cc1ccccc1)c1ccccc11 chemical
c1ccc(CSc2nc3ccccc3n2Cc2ccccn2)cc11 chemical