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Murcko scaffold

Ring system with 4 rings and 24 atoms

49 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
49
With full pages
1
Scaffold SMILES

C(=Cc1nc2ccccc2n1Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1nc2ccccc2n1Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

1-[(2-Chlorophenyl)methyl]-2-[(E)-2-phenylethenyl]benzimidazole chemical structure, C22H17ClN2, CAS 306977-87-7
1-[(2-Chlorophenyl)methyl]-2-[(E)-2-phenylethenyl]benzimidazole
CAS 306977-87-7C22H17ClN2
1-Benzyl-2-[(E)-2-(4-chlorophenyl)ethenyl]benzimidazole chemical structure, C22H17ClN2, CAS 1436431-85-4
1-Benzyl-2-[(E)-2-(4-chlorophenyl)ethenyl]benzimidazole
CAS 1436431-85-4C22H17ClN2
1-[(4-Chlorophenyl)methyl]-2-[(1E)-2-phenylethenyl]-1H-benzimidazole chemical structure, C22H17ClN2, CAS 1053059-01-0
1-[(4-Chlorophenyl)methyl]-2-[(1E)-2-phenylethenyl]-1H-benzimidazole
CAS 1053059-01-0C22H17ClN2
(E)-1-(1-Phenylethyl)-2-styryl-1H-benzo[d]imidazole chemical structure, C23H20N2, CAS 380901-74-6
(E)-1-(1-Phenylethyl)-2-styryl-1H-benzo[d]imidazole
CAS 380901-74-6C23H20N2
1-Benzyl-2-[(E)-2-(2,6-dichlorophenyl)ethenyl]benzimidazole chemical structure, C22H16Cl2N2, CAS 400077-17-0
1-Benzyl-2-[(E)-2-(2,6-dichlorophenyl)ethenyl]benzimidazole
CAS 400077-17-0C22H16Cl2N2
2-(4-Chlorostyryl)-1-(3-(trifluoromethyl)benzyl)-1H-1,3-benzimidazole chemical structure, C23H16ClF3N2, CAS 306977-78-6
2-(4-Chlorostyryl)-1-(3-(trifluoromethyl)benzyl)-1H-1,3-benzimidazole
CAS 306977-78-6C23H16ClF3N2
2-(4-Chlorostyryl)-1-(3,4-dichlorobenzyl)-1H-1,3-benzimidazole chemical structure, C22H15Cl3N2, CAS 306977-79-7
2-(4-Chlorostyryl)-1-(3,4-dichlorobenzyl)-1H-1,3-benzimidazole
CAS 306977-79-7C22H15Cl3N2
2-(4-Chlorostyryl)-1-(2,5-dichlorobenzyl)-1H-1,3-benzimidazole chemical structure, C22H15Cl3N2, CAS 306977-81-1
2-(4-Chlorostyryl)-1-(2,5-dichlorobenzyl)-1H-1,3-benzimidazole
CAS 306977-81-1C22H15Cl3N2
1-(4-(tert-Butyl)benzyl)-2-(4-chlorostyryl)-1H-1,3-benzimidazole chemical structure, C26H25ClN2, CAS 306977-82-2
1-(4-(tert-Butyl)benzyl)-2-(4-chlorostyryl)-1H-1,3-benzimidazole
CAS 306977-82-2C26H25ClN2
1-(2,4-Dichlorobenzyl)-2-styryl-1H-1,3-benzimidazole chemical structure, C22H16Cl2N2, CAS 306977-83-3
1-(2,4-Dichlorobenzyl)-2-styryl-1H-1,3-benzimidazole
CAS 306977-83-3C22H16Cl2N2
1-(2,6-Dichlorobenzyl)-2-styryl-1H-1,3-benzimidazole chemical structure, C22H16Cl2N2, CAS 306977-84-4
1-(2,6-Dichlorobenzyl)-2-styryl-1H-1,3-benzimidazole
CAS 306977-84-4C22H16Cl2N2
1-[(4-Methoxyphenyl)methyl]-2-[(E)-2-phenylethenyl]benzimidazole chemical structure, C23H20N2O, CAS 206982-87-8
1-[(4-Methoxyphenyl)methyl]-2-[(E)-2-phenylethenyl]benzimidazole
CAS 206982-87-8C23H20N2O
1-(4-(tert-Butyl)benzyl)-2-styryl-1H-1,3-benzimidazole chemical structure, C26H26N2, CAS 306977-88-8
1-(4-(tert-Butyl)benzyl)-2-styryl-1H-1,3-benzimidazole
CAS 306977-88-8C26H26N2
1-Benzyl-2-[(E)-2-phenylethenyl]benzimidazole chemical structure, C22H18N2, CAS 1257876-75-7
1-Benzyl-2-[(E)-2-phenylethenyl]benzimidazole
CAS 1257876-75-7C22H18N2
1-[(2-Fluorophenyl)methyl]-2-[(E)-2-phenylethenyl]benzimidazole chemical structure, C22H17FN2, CAS 637753-93-6
1-[(2-Fluorophenyl)methyl]-2-[(E)-2-phenylethenyl]benzimidazole
CAS 637753-93-6C22H17FN2
1-(2-Chloro-6-fluorobenzyl)-2-(2-chlorostyryl)-1H-1,3-benzimidazole chemical structure, C22H15Cl2FN2, CAS 338772-13-7
1-(2-Chloro-6-fluorobenzyl)-2-(2-chlorostyryl)-1H-1,3-benzimidazole
CAS 338772-13-7C22H15Cl2FN2
3-[[2-[(E)-2-(2,4-Dichlorophenyl)ethenyl]benzimidazol-1-yl]methyl]benzonitrile chemical structure, C23H15Cl2N3, CAS 321433-19-6
3-[[2-[(E)-2-(2,4-Dichlorophenyl)ethenyl]benzimidazol-1-yl]methyl]benzonitrile
CAS 321433-19-6C23H15Cl2N3
1-(3-Chlorobenzyl)-2-(2,4-dichlorostyryl)-1H-1,3-benzimidazole chemical structure, C22H15Cl3N2, CAS 321433-20-9
1-(3-Chlorobenzyl)-2-(2,4-dichlorostyryl)-1H-1,3-benzimidazole
CAS 321433-20-9C22H15Cl3N2
1-(2,4-Dichlorobenzyl)-2-(2,4-dichlorostyryl)-1H-1,3-benzimidazole chemical structure, C22H14Cl4N2, CAS 338771-83-8
1-(2,4-Dichlorobenzyl)-2-(2,4-dichlorostyryl)-1H-1,3-benzimidazole
CAS 338771-83-8C22H14Cl4N2
2-(2-Chlorostyryl)-1-(2,6-dichlorobenzyl)-1H-1,3-benzimidazole chemical structure, C22H15Cl3N2, CAS 338772-15-9
2-(2-Chlorostyryl)-1-(2,6-dichlorobenzyl)-1H-1,3-benzimidazole
CAS 338772-15-9C22H15Cl3N2
2-(2,4-Dichlorostyryl)-1-(4-methylbenzyl)-1H-1,3-benzimidazole chemical structure, C23H18Cl2N2, CAS 321433-12-9
2-(2,4-Dichlorostyryl)-1-(4-methylbenzyl)-1H-1,3-benzimidazole
CAS 321433-12-9C23H18Cl2N2
1-[(4-tert-Butylphenyl)methyl]-5,6-dimethyl-2-[(E)-2-phenylethenyl]benzimidazole chemical structure, C28H30N2, CAS 321433-04-9
1-[(4-tert-Butylphenyl)methyl]-5,6-dimethyl-2-[(E)-2-phenylethenyl]benzimidazole
CAS 321433-04-9C28H30N2
1-(3,4-Dichlorobenzyl)-5,6-dimethyl-2-styryl-1H-1,3-benzimidazole chemical structure, C24H20Cl2N2, CAS 321433-05-0
1-(3,4-Dichlorobenzyl)-5,6-dimethyl-2-styryl-1H-1,3-benzimidazole
CAS 321433-05-0C24H20Cl2N2
1-(2,5-Dichlorobenzyl)-2-(2,4-dichlorostyryl)-1H-1,3-benzimidazole chemical structure, C22H14Cl4N2, CAS 338771-81-6
1-(2,5-Dichlorobenzyl)-2-(2,4-dichlorostyryl)-1H-1,3-benzimidazole
CAS 338771-81-6C22H14Cl4N2