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Murcko scaffold

Ring system with 3 rings and 18 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
19
With full pages
4
Scaffold SMILES

c1ccc(Oc2ccc(-c3cscn3)cc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Oc2ccc(-c3cscn3)cc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

2-Methyl-N-[4-(4-phenoxyphenyl)-1,3-thiazol-2-yl]propanamide chemical structure, C19H18N2O2S, CAS 325987-96-0
2-Methyl-N-[4-(4-phenoxyphenyl)-1,3-thiazol-2-yl]propanamide
CAS 325987-96-0C19H18N2O2S
N-[4-(4-Phenoxyphenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C17H14N2O2S, CAS 298194-37-3
N-[4-(4-Phenoxyphenyl)-1,3-thiazol-2-yl]acetamide
CAS 298194-37-3C17H14N2O2S
4-(4-Phenoxy-phenyl)-thiazol-2-ylamine chemical structure, C15H12N2OS, CAS 105512-82-1
4-(4-Phenoxy-phenyl)-thiazol-2-ylamine
CAS 105512-82-1C15H12N2OS
4-[2-Chloro-4-(4-chlorophenoxy)phenyl]-1,3-thiazol-2-amine chemical structure, C15H10Cl2N2OS, CAS 338756-39-1
4-[2-Chloro-4-(4-chlorophenoxy)phenyl]-1,3-thiazol-2-amine
CAS 338756-39-1C15H10Cl2N2OS
4-[2-Chloro-4-(4-chlorophenoxy)phenyl]-2-methyl-1,3-thiazole chemical structure, C16H11Cl2NOS, CAS 338756-41-5
4-[2-Chloro-4-(4-chlorophenoxy)phenyl]-2-methyl-1,3-thiazole
CAS 338756-41-5C16H11Cl2NOS
4-[4-(4-Nitrophenoxy)phenyl]thiazol-2-ylamine chemical structure, C15H11N3O3S, CAS 675602-96-7
4-[4-(4-Nitrophenoxy)phenyl]thiazol-2-ylamine
CAS 675602-96-7C15H11N3O3S
4-(4-(p-Tolyloxy)phenyl)thiazol-2-amine chemical structure, C16H14N2OS, CAS 775578-98-8
4-(4-(p-Tolyloxy)phenyl)thiazol-2-amine
CAS 775578-98-8C16H14N2OS
4-(4-(4-Chlorophenoxy)phenyl)thiazol-2-amine chemical structure, C15H11ClN2OS, CAS 712264-49-8
4-(4-(4-Chlorophenoxy)phenyl)thiazol-2-amine
CAS 712264-49-8C15H11ClN2OS
4-(4-(4-Methoxyphenoxy)phenyl)thiazol-2-amine chemical structure, C16H14N2O2S, CAS 772338-86-0
4-(4-(4-Methoxyphenoxy)phenyl)thiazol-2-amine
CAS 772338-86-0C16H14N2O2S
2-(2-Amino-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid chemical structure, C17H14N2O3S, CAS 91234-20-7
2-(2-Amino-4-(4-phenoxyphenyl)thiazol-5-yl)acetic acid
CAS 91234-20-7C17H14N2O3S
Ethyl 2-bromo-4-(4-phenoxyphenyl)thiazole-5-carboxylate chemical structure, C18H14BrNO3S, CAS 1206908-22-6
Ethyl 2-bromo-4-(4-phenoxyphenyl)thiazole-5-carboxylate
CAS 1206908-22-6C18H14BrNO3S
4-(4-(4-Bromophenoxy)phenyl)thiazol-2-amine chemical structure, C15H11BrN2OS, CAS 925002-19-3
4-(4-(4-Bromophenoxy)phenyl)thiazol-2-amine
CAS 925002-19-3C15H11BrN2OS
2-(2-Acrylamidoethyl)-4-(4-phenoxyphenyl)thiazole-5-carboxamide chemical structure, C21H19N3O3S, CAS 1558036-65-9
2-(2-Acrylamidoethyl)-4-(4-phenoxyphenyl)thiazole-5-carboxamide
CAS 1558036-65-9C21H19N3O3S
2-(2-Aminoethyl)-4-(4-phenoxyphenyl)-5-thiazolecarboxamide chemical structure, C18H17N3O2S, CAS 1558038-32-6
2-(2-Aminoethyl)-4-(4-phenoxyphenyl)-5-thiazolecarboxamide
CAS 1558038-32-6C18H17N3O2S
Ethyl 2-amino-4-(4-phenoxyphenyl)thiazole-5-carboxylate chemical structure, C18H16N2O3S, CAS 899362-76-6
Ethyl 2-amino-4-(4-phenoxyphenyl)thiazole-5-carboxylate
CAS 899362-76-6C18H16N2O3S
4-(4-(4-Fluorophenoxy)phenyl)thiazol-2-amine chemical structure, C15H11FN2OS, CAS 925002-22-8
4-(4-(4-Fluorophenoxy)phenyl)thiazol-2-amine
CAS 925002-22-8C15H11FN2OS
2-Bromo-4-(4-phenoxyphenyl)thiazole chemical structure, C15H10BrNOS, CAS 1188165-10-7
2-Bromo-4-(4-phenoxyphenyl)thiazole
CAS 1188165-10-7C15H10BrNOS
4-(4-Phenoxyphenyl)-1,3-thiazol-2-amine hydrochloride chemical structure, C15H13ClN2OS, CAS 79615-33-1
4-(4-Phenoxyphenyl)-1,3-thiazol-2-amine hydrochloride
CAS 79615-33-1C15H13ClN2OS
4-(3-Chloro-4-phenoxyphenyl)-2-thiazolamine chemical structure, C15H11ClN2OS, CAS 105512-84-3
4-(3-Chloro-4-phenoxyphenyl)-2-thiazolamine
CAS 105512-84-3C15H11ClN2OS